[Immunity and the prostaglandin level in gastritis B]. / Sostoianie immuniteta i uroven' prostaglandinov pri gastrite B.

The indices of systemic and local immunity, level of prostaglandins, presence of Helicobacter pylori in the gastric mucosa was studied in 53 patients with gastritis B. Patients with superficial antral gastritis showed independent of the presence of Helicobacter pylori in the gastric mucosa changes of the systemic immunity and level of PGE2 and PGF1 that were abnormal. In atrophy of the antral gastric mucosa and presence there of H. pylori one observed a reduction of the number of T-lymphocytes and proliferative activity. Suppression of the system of prostaglandins in the blood and gastric mucosa, the toxic effect of H. pylori results in autosensibilization, increase of IgA and IgG finally leading to development of erosions in the gastric antrum.

[Blood gastrin and ultrastructure of gastrin-producing cells in chronic gastritis with secretory insufficiency]. / Soderzhanie gastrina v krovi i ul'trastructura gastrinprodutsiruiushchikh kletok pri khronicheskom gastrite s sekretornoi nedostatochnost'iu.

The content of basal gastrin and ultrastructure of gastrinproducing cells was studied in 81 patients showing chronic gastritis with secretory insufficiency. The highest level of gastrin was revealed in the blood of patients with diffuse atrophic gastritis, moderately increased--focal atrophic gastritis. The blood gastrin was reduced in patients with antral gastritis. A study of the ultrastructure of gastrinproducing cells revealed their high functional activity in diffuse atrophic gastritis and a moderate in focal atrophic gastritis. Changes of the gastrin level and ultrastructure of gastrinproducing cells should be considered in the choice of treatment methods.