[The application of hemoreologic indicators in prognosis of complications of acute myocardium infarction].

The sampling of 60 patients with acute myocardium infarction underwent a complex study of hemoreologic indicators with purpose to establish predictors of development of early complications of diseases to substantiate additions to algorithm of examination and to differentiate treatment regimens. It is established that under acute myocardium infarction the blood viscosity increases on low velocity of shifting and plasma. Also, the process of aggregation of erythrocytes increases and number of normocytes decreases without significant alterations of blood viscosity on high velocity of shift and capacity of erythrocytes to be distorted. At the same time, the mentioned above alterations in patients with acute myocardium infarction does not result in decreasing of effectiveness oftransportation of oxygen to tissues. Against the background of development the hemoreologic disorders have more apparent character and result in progressive decreasing of tissue perfusion. The most significant prognostic indicator concerning complications of acute myocardium infarction is a time parameter of increment of aggregation of erythrocytes surpassing 2.80 in 89% of patients with complications. The expedience of inclusion of detection of reologic blood indicators fir their subsequent correction in the complex of examination ofpatients with acute myocardium infarction.

[Outpatient follow-up and management of pregnant women with hypertension].

AIM: To study variants of the course of chronic hypertension in pregnant women and determination of factors predisposing to a persistent rise of arterial pressure (AP) in pregnancy. MATERIAL AND METHODS: A total of 50 pregnant women were examined (heart rhythm variability and psychological testing) who had AP 140/90 mm Hg and higher as shown by measurements at three outpatient check-ups. After delivery the patients were retrospectively devided into two groups. Twenty-seven group 1 women had frequent rises of AP to 140/90 and higher throughout pregnancy; twenty-three women of group 2 had high AP only at early terms of pregnancy, later they became normotensive without use of hypotensive drugs. 24-h AP monitoring was made in 29 patients. By its results, two subgroups were identified: 11 patients with essential hypertension and 18 women with neurocirculatory dystonia by hypertensive type. RESULTS: In group 1 there was an early fall of cardiac performance, higher values of SMIP test according to scales 2 (pessimism), 3 (emotional lability), 4 (impetuosity) and 7 (anxiety). CONCLUSION: The analysis of 24-h AP profiles revealed more persistent and significant rise of AP in patients with essential hypertension than in those with neurocirculatory dystonia. They also demonstrated high AP variability correlating with a risk of cardiovascular diseases.

[Life quality in patients with early hypertensive disease]. / Kachestvo zhizni bol'nykh s nachal'noi stadiei gipertonicheskoi bolezni.

Thirty-seven males aged 18 to 55 years (mean age 29.6 +/- 1.8 years) who had a 1-3-year history of arterial hypertension (AH) were examined. All the patients were found to have grade 1 hypertension. Life quality (LQ) was studied using the questionnaire developed by the Ivanovo State Medical Academy in 2000. A significant decrease in LQ was found at the peak of AH in the patients as compared with healthy individuals; however, the specific parameters of the health status and reductions in their functional capacities differed slightly. It is concluded that it is necessary to apply a standardized approach to assessing the patients' complaints and medical history data.

[Diagnostics of disorders in lipid and carbohydrate metabolism in women with hypertension in outpatient clinic]. / Diagnostika v ambulatornykh usloviiakh narushenii lipidnogo i uglevodnogo obmena u zhenshchin s gipertonicheskoi bolezn'iu.

AIM: To study lipid and carbohydrate metabolism in young and middle-aged women with essential hypertension (EH). MATERIAL AND METHODS: Anthropometric parameters, arterial pressure (AP), glucose tolerance (GT), fasting glucose, immunoreactive insulin (IRI), glycosylated hemoglobin (HbA1), total cholesterol (TC), triglycerides (TG), HDLP cholesterol, atherogenic index were estimated in 93 women aged 20 to 50 years with EH stage II. RESULTS: TC was elevated in 75%, HDLP cholesterol--in 52%, TG--in 40% patients. Subnormal HDLP was only in 8% examinees. 6, 4, 21% of 53 examinees had elevated fasting glucose, GT, HbA1, respectively. Hyperinsulinemia was detected in 80%, insulin resistance in 92%. CONCLUSION: Disturbances of lipid metabolism were identified in more than half of the examined EH women. The HbA1 test is more sensitive than GT and fasting glucose tests in detection of abnormal carbohydrate metabolism.