ABSTRACT
An epidemiological and serological study was carried out on a sample of 2,180 individuals, in five counties in the north of Paraná State-Brazil, using the indirect immunofluorescence test to detect anti-Cysticercus cellulosae antibodies. These individuals, 69 (3.2%) showed significant titers of antibodies. No single significant difference between the proportion of reactivity in Sarandi (6.6%) and in Marialva (4.7%) was observed (Z = 1,319, P = 0.0936), but it was significantly higher than that observed in Mandaguaçu, Paiçandu and Maringá (P < 0.01). Of these individuals, 47.9% were within 21-49 years old and 79.4% were of female sex. "Headache" (70.6%), "faintness" (57.4%), and "convulsions" (7.4%) were among the most frequent by reported, moreover, cases of Taenia infections (22.1%) and the custom of eating uncooked beef (41.2%) or pork (27.9%) and meat containing cysticerci (25.0%) were also related.
Subject(s)
Antibodies, Helminth/blood , Cysticercus/immunology , Adolescent , Adult , Animals , Brazil/epidemiology , Child , Cysticercosis/blood , Cysticercosis/epidemiology , Feces/parasitology , Female , Humans , Male , Middle Aged , Seroepidemiologic StudiesABSTRACT
A leishmaniose tegumentar tem mostrado carater endemico no Norte-Nordeste do Parana, em areas que vem sendo ocupadas desde os anos 40, onde persistem matas residuais com modificacoes bastante acentuadas. A infeccao tem atingido sobretudo adultos do sexo masculino, mas tambem vem sendo constatada em mulheres e criancas, e por vezes em diversos componentes de uma mesma familia. Investigou-se 513 casos de leishmaniose tegumentar notificados pela SUCAM, com informacoes de terem tido apenas diagnostico clinico, de janeiro de 1987 a agosto de 1989, os quais iniciaram o tratamento com "Glucantime POT. R", em Centros de Saude do Estado ou na propria SUCAM. De 513 pacientes tratados 260 (50,67 por cento) tiveram alta por cura clinica e os 253 (49,33 por cento) nao retornaram para a verificacao da cura clinica ou abandonaram o tratamento. A quantidade de ampolas de "Glucantime POT. R" fornecidas para os pacientes oscilou de 10 a mais de 200, com ou sem intervalo durante o tratamento, sendo que 217 (85,46 por cento) dos 260 casos receberam de 10 a 75 ampolas. A ocorrencia de leishmaniose em 163 (31,75 por cento) mulheres e em 34 (6,62 por cento) criancas, de ambos os sexos, ate dez anos de idade, sugere a transmissao domiciliar. Nao se sabe se os 253 (49,33 por cento) individuos que nao retornaram ou abandonaram o tratamento seguiram a prescricao terapeutica e se restabeleceram...
Subject(s)
Child, Preschool , Child , Adult , Male , Female , Infant , Adolescent , Middle Aged , Humans , Leishmaniasis, Cutaneous/drug therapy , Meglumine/therapeutic use , Organometallic Compounds/therapeutic use , Brazil/epidemiology , Disease Notification , Leishmaniasis, Cutaneous/epidemiologyABSTRACT
American cutaneous leishmaniasis has shown an endemic character in areas of North-North-west Paraná State, which were populated in 40's, where residual forests persist with intense modifications. The infection has been found mainly in males, but was found also in females and children and in many individuals of a same family. 513 cases of cutaneous leishmaniasis notified to SUCAM by clinical diagnosis were investigated. Treatment was begun with Glucantime at State Health Centers or at SUCAM. Of 513 treated patients 260 (50.67%) were considered clinically cured. The remaining 253 (49.33%) abandoned treatment. The quantity of Glucantime supplied to the patients varied from 10 vials to more than 200, with or without intervals during the treatment. Two hundred and seventeen (85.46%) patients among 260 received from 10 to 75 vials. The occurrence of leishmaniasis in 163 (31.75%) women and in 34 (6.62%) children, of both sexes, up to 10 years old, suggests domiciliary transmission. It's not known if the 253 (49.33%) individuals who abandoned the treatment recovered. This high number shows the necessity of better knowledge of the consequences that can occur due to incomplete treatment.
Subject(s)
Leishmaniasis, Cutaneous/drug therapy , Meglumine/therapeutic use , Organometallic Compounds/therapeutic use , Adolescent , Adult , Aged , Brazil/epidemiology , Child , Child, Preschool , Female , Humans , Infant , Leishmaniasis, Cutaneous/epidemiology , Male , Meglumine Antimoniate , Middle Aged , RegistriesABSTRACT
Most of the cases of cutaneous leishmaniasis diagnosed in the laboratory of the State University of Maringá, Paraná, Brazil, are related to areas of northern Paraná State, which have been settled since 40 years age, when the destructions of vast areas of forest in this region was begun. The native vegetation, already, in large part, destroyed is constituted of dense forest of the type found in the transition from tropical to subtropical regions. The landscape is constituted of plateau with a climate of transition from tropical to subtropical and annual mean temperatures of 20 degrees C to 22 degrees C, the mean of the hottest month being superior to 22 degrees C. The native forests are represented by small, sparse patches of vegetation, with some modification in the basins of the rivers Ivaí, Paranapanema and Paraná and their tributaries. In this environment 24 captures of phlebotomines were made--2 per month from October 1986 to September 1987, between 6 P.M. and 1 A.M. The captures with Shannon trap were made in the outlying forest of Palmital farm. The majority of the 16,496 phlebotomines were classified into 13 species. Lutzomyia whitmani was predominant with 11,188 (67.82%) specimens, followed by Lutzomyia intermedia with 2,900 (17.58%) and Lutzomyia migonei with 1,481 (9.03%). Lutzomyia whitmani and Lutzomyia intermedia have been manifesting great capacity of adaptation in modified environments, where they have played a significant role in transmission of leishmaniasis.
