[The use of thienam for the emergency antibacterial therapy of acute suppurative pyelonephritis]. / Zastosuvannia tiienamu dlia ekstrenoï antybakterial'noï terapiï hostroho hniinoho piielonefrytu.

Results of a clinical and microbiological investigation designed to study thienam permit recommending this drug as an urgent agent of choice in acute purulent pyelonephritis. The drug is well tolerated. Among other benefits is extremely high sensitivity of bacteria (pathogenic and conditionally pathogenic) to the medication, achievement of an expected clinical effect within a short time since its therapy institution.

[The validation of empirical emergency antibacterial therapy in acute pyelonephritis]. / Obhruntuvannia ekstrenoï empirychnoï antybakterial'noï terapiï pry hostromu piielonefryti.

As many as 254 patients with acute pyelonephritis were evaluated for the whole range of possible inflammatory process pathogens with the aid of automatic microbiological system [symbol: see text]. Urine from the urinary bladder, renal pelves (as directed) was studied as was biopsy specimen of the kidney. Analysis of species range of the identified organisms showed Escherichia coli, Proteus, and mycoplasma, enterobacter, coccal flora and pseudomonads to be in 27.9%, 15.9%, 14.9%, 8.6%, and 5.5% respectively. Analysis of sensitivity of the discovered bacteria toward a wide range of antibacterial preparations permitted recommending for an urgent antiinflammatory therapy thienam, ophloxacin, cyprophloxacin, pephloxacin, norphloxacin, cephoxitin, and cephtriaxone. The form of the preparation (parenteral or peroral) will be prescribed depending upon the gravity of the course of acute pyelonephritis.