Subject(s)
Gastrointestinal Diseases/diagnosis , IgA Vasculitis/diagnosis , Kidney Diseases/diagnosis , Skin Diseases/diagnosis , Combined Modality Therapy , Diagnosis, Differential , Gastrointestinal Diseases/classification , Gastrointestinal Diseases/therapy , Humans , IgA Vasculitis/classification , IgA Vasculitis/therapy , Kidney Diseases/classification , Kidney Diseases/therapy , Skin Diseases/classification , Skin Diseases/therapySubject(s)
Anemia, Hypochromic/diagnosis , Erythrocytes/chemistry , Ferrous Compounds/administration & dosage , Hemoglobins/analysis , Iron Deficiencies , Administration, Oral , Anemia, Hypochromic/drug therapy , Anemia, Hypochromic/prevention & control , Diagnosis, Differential , Erythrocytes/drug effects , Female , Humans , Iron/administration & dosage , Iron/blood , Male , Severity of Illness Index , Sex FactorsABSTRACT
Erythropoietin level in the blood plasma, iron metabolism, and some erythron parameters characterizing anemia expression, erythropoiesis effectiveness and processes of hemoglobin synthesis were studied in patients with iron-deficiency anemia (IDA). The results of the investigation helped the authors to establish that hormone production in IDA patients is under the control of a feedback mechanism that is functioning at a lower level as compared to other non-renal anemias. It has been suggested that optimum possible erythron functioning in IDA patients is achieved under these conditions.
Subject(s)
Anemia, Hypochromic/blood , Erythrocytes/pathology , Erythropoiesis/physiology , Hemoglobins/biosynthesis , Adolescent , Adult , Erythrocyte Count , Erythrocytes/metabolism , Female , Humans , Iron/blood , Middle AgedSubject(s)
Anemia, Hypochromic/diagnosis , Iron Deficiencies , Adolescent , Adult , Anemia, Hypochromic/blood , Diagnosis, Differential , Female , Ferritins/blood , Ferritins/deficiency , Hemoglobins/analysis , Humans , Iron/blood , Male , Middle Aged , Sex Factors , Time FactorsABSTRACT
Iron metabolism was studied in patients with chronic diffuse diseases of the liver. A sharp increase of ferritin content at the expense of its release from affected hepatocytes, and formation of antibodies to ferritin of the splenic type have been recorded in patients with cirrhosis of the liver. The observed growth of ferritin content in red blood cells can be explained by functional deficiency of red blood cells and by the presence of hemolytic process (twofold decrease of haptoglobin level). A conclusion has been made that ferritin content in the blood serum does not correlate with the total iron reserves, and serum ferritin level should be considered not as a sign of the pathologic process, but as an index of iron reserves capable of participating in metabolic processes.
Subject(s)
Ferritins/metabolism , Hepatitis, Chronic/metabolism , Iron/metabolism , Liver Cirrhosis/metabolism , Liver/metabolism , Adult , Aged , Chronic Disease , Female , Ferritins/chemistry , Humans , Iron/chemistry , Male , Middle AgedSubject(s)
Postoperative Complications/diagnosis , Prostatic Hyperplasia/surgery , Thromboembolism/diagnosis , Aged , Chronic Disease , Disseminated Intravascular Coagulation/blood , Disseminated Intravascular Coagulation/diagnosis , Disseminated Intravascular Coagulation/etiology , Disseminated Intravascular Coagulation/prevention & control , Hemostasis , Humans , Male , Peptide Hydrolases/blood , Postoperative Complications/blood , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Prostatectomy , Prostatic Hyperplasia/blood , Prostatic Hyperplasia/complications , Thromboembolism/blood , Thromboembolism/etiology , Thromboembolism/prevention & controlABSTRACT
The results of the overtime combined clinico-laboratory investigations have evidenced a high medical effectiveness of red blood cell pack transfusions in the treatment of anemia in patients with varying diseases of internal organs.
Subject(s)
Anemia, Hypochromic/therapy , Blood Transfusion/methods , Erythrocyte Transfusion , Internal Medicine , Anemia, Hypochromic/blood , Blood Preservation , Evaluation Studies as Topic , HumansABSTRACT
The paper covers present-day methods of diagnosis, treatment, primary and secondary prophylaxis of iron deficiency anemia. Serum ferritin determination useful for evaluating total iron deposits in the body is thought to allow early diagnosis. Oral administration of iron preparations is recommended as more advantageous. It is emphasized that the disease treatment should not be discontinued after recovery of normal hemoglobin values. The next therapeutic measures are to provide normal levels of serum iron and ferritin.
Subject(s)
Anemia, Hypochromic/drug therapy , Ferritins/blood , Ferrous Compounds/therapeutic use , Anemia, Hypochromic/blood , Anemia, Hypochromic/prevention & control , Drug Evaluation , Female , Ferrous Compounds/administration & dosage , Humans , Iron/blood , Male , Monitoring, PhysiologicSubject(s)
Hepatitis/therapy , Liver Cirrhosis/therapy , Plasma Substitutes/therapeutic use , Adult , Chronic Disease , Combined Modality Therapy/methods , Drug Evaluation , Drug Therapy, Combination , Hepatitis/blood , Hepatitis/complications , Humans , Inactivation, Metabolic , Liver Cirrhosis/blood , Liver Cirrhosis/complications , Male , Parenteral Nutrition , Protein Deficiency/blood , Protein Deficiency/etiology , Protein Deficiency/therapyABSTRACT
Therapeutic action of blood components, preparations and substitutes was studied in liver cirrhosis patients with deep anemia, marked hemorrhagic complications, endogenous toxicosis, protein insufficiency and rheological disorders. A high efficacy of different media was shown in urgent therapy of liver cirrhosis patients. A choice of drugs was determined by the patients' initial status and specificities of purpose-oriented action of modern transfusion and infusion media.
Subject(s)
Blood Substitutes/therapeutic use , Blood Transfusion , Liver Cirrhosis/therapy , Adult , Anemia/therapy , Blood Coagulation , Emergencies , Hemorrhage/therapy , Humans , Liver Cirrhosis/blood , Liver Cirrhosis/complications , MaleSubject(s)
Alcoholism/blood , Ethanol/adverse effects , Hematopoiesis/drug effects , Alcoholism/complications , Female , Humans , MaleSubject(s)
Anemia/therapy , Blood Transfusion , Erythrocyte Transfusion , Adolescent , Adult , Aged , Blood Preservation , Female , Humans , Male , Middle Aged , Time FactorsABSTRACT
On the basis of the clinicophysiological and biochemical-hematologic investigations it was established that the feeding of infants with the adapted mixture "Malysh" did not prevent the development of latent iron deficiency in them. This was the reason for the enrichment of the mixture with hemopoietic substances. Five formulas of the mixture with varying compositions of hemopoietic factors enabled the authors to establish the optimum variant of the ratio of these ingredients in the adapted milk mixture. The use of the adapted mixtures enriched with hemopoietic substances promotes the prevention of iron deficiency that is confirmed by the increase of the hemoglobin stock and iron reserves in the child's body. The levels of blood hemoglobin and serum ferritin serve as informative values evidencing the effectiveness of using food enriched with hemopoietic factors.
