ABSTRACT
The proposed method or re-embedding tissue specimens from paraffin in epoxy resins (epon, araldite, etc.) permits study of the same material at histo-, cyto-, and ultrastructural levels by modern morphological methods and thus detecting a number of additional morphological signs important for thanatogenesis. The proposed method provides objective results and improves the quality of forensic medical studies in general.
Subject(s)
Microscopy, Electron/methods , Paraffin Embedding/methods , Plastic Embedding/methods , Forensic Medicine/methods , Humans , Time FactorsABSTRACT
Morphofunctional myocardial characteristics in subjects who died of acute and chronic alcoholic intoxication were studied at ultrastructural level. The resulting new data enhance the level of diagnosis concerning the cause of death, the grounds of thanatogenesis. Possibilities for using the results of investigation in scientific and practical work are shown.
Subject(s)
Alcoholic Intoxication/physiopathology , Alcoholism/physiopathology , Heart/physiopathology , Myocardium/ultrastructure , Adult , Alcoholic Intoxication/mortality , Alcoholism/mortality , Cause of Death , Coronary Disease/mortality , Coronary Disease/pathology , Death, Sudden/pathology , Ethanol/analysis , Female , Humans , Male , Microscopy, Electron , Middle AgedABSTRACT
The study was performed on 20 guinea-pigs. The animals were injured by alternating current at 380 and 220 V. The developing destructive alterations were characterized by histological, histochemical and electron-microscopic techniques, and a complex of electric markers was established. A dependence of morphological changes on the voltage values was demonstrated. The complex of alterations found may be employed for the differentiation of electric markers from mechanical or thermal injuries.
Subject(s)
Electric Injuries/pathology , Skin/ultrastructure , Animals , Electric Injuries/metabolism , Guinea Pigs , Male , Microscopy, Electron , Periodic Acid-Schiff Reaction , Skin/metabolismSubject(s)
Autolysis/pathology , Death , Kidney/ultrastructure , Lung/ultrastructure , Animals , Cytoplasm/ultrastructure , Humans , Rats , Time FactorsABSTRACT
Histologic and electron-microscopic examination of the liver, heart, kidneys, lungs of 32 individuals who died from acute alcoholic intoxication (alcoholemia from 2,9 to 7,2 0/00) and 16 people who died suddenly from a trauma being in the state of a severe alcoholic intoxication. Material was taken for the examination within 3 hours after death. The ultrastructural alterations detected in the organs reflect a deep metabolic disturbances resulting from an acute or chronic alcoholic intoxication. The relation of morphological changes with an age and an alcohol abuse duration is discussed.
Subject(s)
Alcoholic Intoxication/pathology , Kidney/ultrastructure , Liver/ultrastructure , Lung/ultrastructure , Myocardium/ultrastructure , Adult , Forensic Medicine , Humans , Microscopy, Electron , Middle Aged , Organoids/ultrastructureSubject(s)
Clomiphene/therapeutic use , Cresols/therapeutic use , Cyclofenil/therapeutic use , Infertility, Female/drug therapy , Adult , Amenorrhea/drug therapy , Chronic Disease , Clinical Trials as Topic , Clomiphene/administration & dosage , Cyclofenil/administration & dosage , Female , Humans , Menstruation Disturbances/drug therapy , Ovulation Induction/methods , Polycystic Ovary Syndrome/drug therapyABSTRACT
The selective character of staining the intact mucosa with Lugol's solution is dependent on the glycogen content in the superficial epithelial layer of the oesophagus. The inflammatory or carcinomatous epithelium being not stained is accounted for by changes in the glycogen content in the oesophageal epithelium which makes the staining method useful for diagnozing carcinomatous and inflammatory diseases of the oesophagus.
Subject(s)
Esophageal Neoplasms/diagnosis , Esophagitis/diagnosis , Iodine , Mucous Membrane/drug effects , Potassium Iodide , Adult , Aged , Diagnosis, Differential , Esophagoscopy/methods , Humans , Middle Aged , Solutions , Staining and Labeling/methodsABSTRACT
PIP: To evaluate a possible risk of development of inflammatory diseases of the genital organs in IUD users, 410 women in whom IUD was inserted on day 5 after normal delivery were followed up for 3 years. The follow-up included gynecologic, colposcopic, and bacteriologic examinations. IUD insertion shortly after childbirth did not affect the course of the puerperal period. Within the 1st 3-6 months, 13% of the women showed expulsion of the IUD and had to undergo the reinsertion of the device. The IUD did not increase the incidence of vaginal discharge (6%, compared with 6.3% reported in the literature). Bacteriologic examination of the vaginal and cervical content showed prevalence of cocci and gram-positive bacteria identical to those in women who did not use the IUD. Histological examination of the endometrium in 65 women indicated chronic endometritis in 4 and foci of the perivascular and periglandular round cell and leukocytic infiltration indicative of a local nonspecific immune response to the foreign body in 26. Among these 65 women, 15 showed proliferative phase of the endometrium, 24 showed early secretory phase and 26 showed secretory phase. The state of the endometrium corresponded to the phase of the menstrual cycle in 41 of 65 women. It was concluded that the incidence of complications in women subjected to IUD insertion after childbirth did not exceed that of the general population.^ieng
Subject(s)
Genital Diseases, Female/epidemiology , Intrauterine Devices/adverse effects , Pelvic Inflammatory Disease/etiology , Puerperal Infection/epidemiology , Adult , Endometrium/pathology , Female , Genital Diseases, Female/etiology , Genital Diseases, Female/microbiology , Humans , Middle Aged , Pregnancy , Puerperal Infection/etiology , Puerperal Infection/microbiology , Risk , Time FactorsABSTRACT
Experiments were conducted on albino rats; a study was made of hyperplastic processes in the mitochondria of the myocytes of the heart with the action of toxic adrenaline doses. A solution of adrenaline chloride was injested intramuscularly (3 mg/kg). Three types of mitochondria were revealed in electron microscopic study. Mitochondria of the first type were of the size and structure characteristic of the muscle cells of the myocardium. Mitochondria of the second type had a very dense, finegrained matrix and a great number of cristae per unit of the area. Mitochondria of the third type had two "sections" under the common external membrane, differing from one another by the matrix density, distribution and number of cristae. It is supposed that the ultrastructural peculiarities of each of the types reflected their functional condition.