1.
Bull Exp Biol Med
; 137(6): 588-91, 2004 Jun.
Article
in English
| MEDLINE
| ID: mdl-15455093
ABSTRACT
Vilon stimulated and Epithalon suppressed the expression of argyrophilic proteins in nucleolar organizer regions of thymocytes and epithelial cells, stimulating or reducing, respectively, the formation, assembly, and transport of ribosomes into the cytoplasm and thus determining the intensity of protein synthesis in these cells. A direct mitogenic effect of Vilon was also revealed: this peptide promoted thymocyte transformation into proliferating blast cells.