1.
Pharmacopsychiatry
; 49(2): 76-8, 2016 Mar.
Article
in English
| MEDLINE
| ID: mdl-26797932
ABSTRACT
In this article a case of carbamazepine overdose is reported. It is common to use immuno-based methods in the field of therapeutic drug monitoring but it might be difficult to adapt such values to toxicological cases. For carbamazepine overdoses it is recommended also to determine the metabolite carbamazepine-10,11-epoxide. Especially for critical conditions a definite substance identification should be performed. In addition, quantifying main metabolites is recommended for an acute clinical toxicological assessment.