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Gan To Kagaku Ryoho ; 43(5): 613-5, 2016 May.
Article in Japanese | MEDLINE | ID: mdl-27210093

ABSTRACT

A 69-year-old man visited a clinic for left leg weakness. With suspicions of lung cancer and a metastatic brain tumor, he was referred to our hospital and was diagnosed with large cell neuroendocrine carcinoma, cT1bN0M1b (BRA), stage IV. After stereotactic radiosurgery for his brain metastasis, he was treated with chemotherapy containing cisplatin and irinotecan. A week after initiating chemotherapy, he suddenly developed severe right leg pain and adynamia. A computed tomography angiogram revealed occlusion of the right common femoral artery, and percutaneous thrombectomy was performed. The symptoms resolved completely, and he was discharged without any sequelae or recurrence. Acute arterial occlusion of the limbs during chemotherapy is uncommon and requires prompt diagnosis and treatment; hence, caution should be paid when it is clinically suspected.


Subject(s)
Arterial Occlusive Diseases/etiology , Lower Extremity , Lung Neoplasms/drug therapy , Aged , Anticoagulants/therapeutic use , Arterial Occlusive Diseases/drug therapy , Arterial Occlusive Diseases/surgery , Heparin/therapeutic use , Humans , Lung Neoplasms/complications , Male , Thrombectomy , Warfarin/therapeutic use
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