Subject(s)
Antiviral Agents/adverse effects , Interferon-beta/adverse effects , Macular Edema/chemically induced , Retinal Diseases/chemically induced , Adult , Fluorescein Angiography , Fundus Oculi , Hepatitis C, Chronic/drug therapy , Humans , Macular Edema/physiopathology , Male , Retinal Diseases/physiopathology , Visual AcuityABSTRACT
A 31-year-old female presented with cavernous angioma originating from the optic chiasm manifesting as sudden onset of right retroorbital pain and right visual disturbance. She had a psychomotor seizure 10 years ago. Cavernous angioma at the right basal ganglia had been partially removed at that time. After the operation, the patient had left hemiparesis, but gradually improved. Neurological examination revealed decreased right visual acuity, left homonymous hemianopsia, and left hemiparesis. Magnetic resonance imaging revealed a mixed signal intensity mass at the right optic nerve to the optic chiasm with a low signal intensity rim on T2-weighted imaging, situated at the right basal ganglia where the cavernous angioma had been partially resected. Right frontotemporal craniotomy was performed by the pterional approach. A subpial hematoma was situated at the right optic nerve to the optic chiasm. The hematoma with an angiomatous component was completely resected from the surrounding structure. Histological examination of the specimens confirmed cavernous angioma. Postoperatively, her right visual acuity was slightly improved, but the visual field defect was unchanged. We emphasize the importance of correct diagnosis by magnetic resonance imaging and subsequent resection for preserving and improving the visual function of patients with cavernous angiomas of the optic chiasm.
Subject(s)
Cranial Nerve Neoplasms/surgery , Hemangioma, Cavernous/surgery , Optic Chiasm/surgery , Adult , Cranial Nerve Neoplasms/diagnosis , Cranial Nerve Neoplasms/pathology , Female , Hemangioma, Cavernous/diagnosis , Hemangioma, Cavernous/pathology , Humans , Magnetic Resonance Imaging , Optic Chiasm/pathology , Prognosis , Visual Fields/physiologyABSTRACT
Growth of a single sugi (Cryptomeria japonica (L.f.) D. Don.) tree was analyzed on the basis of a dry matter budget. The aboveground net production rate and death rate were defined as the anabolic rate and catabolic rate, respectively. Growth rate of aboveground tree weight, v(w) (kg(dw) year(-1)), was defined as follows: v(w) = v(p) - v(d) (1) where v(p) (kg(dw) year(-1)) is the aboveground net production rate and v(d) (kg(dw) year(-1)) is the aboveground death rate. The value of v(d) is obtained by measuring the monthly clippings of new dead leaves and branches attached to a sample tree. The value of v(w) was calculated as the annual difference in the estimated aboveground tree weight, w(T) (kg(dw)). Finally, the value of v(p) was estimated as the sum of the values of v(d) and v(w). The following allometric relationships were found between v(p) and w(T) and between v(d) and w(T): v(p) = aw(T) (alpha), v(d) = bw(T) (beta) (2). Combining Equations 1 and 2 gives a growth equation, Bertalanffy's equation, of the sample tree. dw(T)/dt = v(w) = aw(T) (alpha) - bw(T) (beta) (3). Because the growth curve of w(T) was derived from Equation 3, the analysis of the growth of w(T) is based on direct measurement of the dry matter budget.
ABSTRACT
In our previous work a new method for the cross-linking of protein was proposed. The method is based on the spontaneous chelate formation process between salicylaldehyde and alpha-amino acid residues. Thus, the facile procedure for the introduction of these residues into protein is required. In this paper, a modification reagent which affords gamma-glutamylation products, i.e., introducing an alpha-amino acid functional group to the protein was proposed. Versatility of the reagent for the preparation of a cross-linked enzyme was examined.