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1.
Tohoku J Exp Med ; 235(2): 111-5, 2015 02.
Article in English | MEDLINE | ID: mdl-25749491

ABSTRACT

The rate of breast cancer mortality in Okinawa has gradually been increasing up to 2010. Now Okinawa has the second worst mortality rate in Japan, in part due to the enormous dietary changes resulting from the post-World War II US military occupation, high incidence of obesity, high non-optimal treatment rate, and low breast-cancer screening rate. To reduce breast cancer mortality in Okinawa, we established the Okinawa Breast Oncology Meeting (OBOM) in 2012. At the 7th OBOM held on January 10th, 2014, we discussed the breast cancer mortality in Okinawa focusing on lifestyle, breast cancer screening and optimal treatments. The Okinawan women who were overweight and/or obese during premenopausal and postmenopausal ages had a statistically significant higher risk of breast cancer development compared to those with non-overweight and/or obese women. The traditional diet of Okinawa consists of foods low in calories but rich in nutritional value. Therefore, we recommend Okinawan people not to forget the Okinawan traditional lifestyle, and to reduce their bodyweight to prevent breast cancer. One of the main goals of the OBOM is to raise breast cancer screening attendance rates to 50% (29.2% in 2010). We should standardize the quality control for breast cancer screening in Okinawa. It is important to continue enlightening the Okinawan population to receive optimal treatment. In addition, we are striving to establish systematic medical cooperation between the hospitals specializing in breast cancer treatment with rural hospitals. The OBOM group endeavors to contribute to the improvement of breast cancer mortality in Okinawa.


Subject(s)
Breast Neoplasms/mortality , Breast Neoplasms/diagnosis , Breast Neoplasms/therapy , Early Detection of Cancer , Female , Humans , Japan/epidemiology , Life Style
2.
Jpn J Clin Oncol ; 43(2): 208-13, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23288933

ABSTRACT

Breast cancer mortality is gradually increasing in Okinawa. The 1st Okinawa Breast Oncology Meeting was held on 6 July 2012 and discussions on how to curb the rising trend were focused on breast cancer screening, adjuvant treatment, socioeconomic and geographic issues, and the problem of complementary and alternative medicine. The consensus of the 1st Okinawa Breast Oncology Meeting was that ultrasonography screening is an acceptable screening system for Okinawan women because of the geographic disadvantage of having many small islands and rural areas. Educational and economic support is needed for women in rural areas to get correct information, for access to urban areas and to be treated by evidence-based optimal therapy for breast cancer. In addition, new approaches are needed for Okinawan people to successfully educate patients to correctly interpret evidence-based information.


Subject(s)
Asian People/statistics & numerical data , Breast Neoplasms/mortality , Breast Neoplasms/prevention & control , Mammography , Mass Screening/methods , Ultrasonography, Mammary , Adult , Aged , Breast Neoplasms/diagnostic imaging , Breast Neoplasms/epidemiology , Educational Status , Female , Healthcare Disparities , Humans , Income , Japan/epidemiology , Middle Aged , Palpation , Patient Acceptance of Health Care , Poverty , Sensitivity and Specificity , Socioeconomic Factors , Unemployment
3.
Gan To Kagaku Ryoho ; 37(9): 1795-7, 2010 Sep.
Article in Japanese | MEDLINE | ID: mdl-20841950

ABSTRACT

Recently, several reports have been made concerning topical use of Mohs paste for local recurrence of breast cancer tumors. Since January 2008, after the introduction of Mohs paste for palliation in patients with local recurrences of breast cancer, we have encountered some problems such as pain, draining off of the paste and ulceration of the lesion. In this study, we have reported the advantages and disadvantage of using Mohs paste, the difference in the procedure depending on the purpose, and the management of problems. When using Mohs paste for the purpose of palliative therapy, these side effects are problems we should not ignore to prevent patient pain.


Subject(s)
Breast Neoplasms/complications , Neoplasm Recurrence, Local/complications , Skin Ulcer/drug therapy , Aged, 80 and over , Female , Humans , Middle Aged , Ointments/therapeutic use , Skin Ulcer/etiology
4.
Gan To Kagaku Ryoho ; 33(4): 509-11, 2006 Apr.
Article in Japanese | MEDLINE | ID: mdl-16612163

ABSTRACT

A 72-year-old female with scirrhous-type advanced gastric cancer was treated with TS-1/CDDP as neoadjuvant chemotherapy. TS-1 (80 mg/m(2)/day) was orally administered for 3 weeks and CDDP (60 mg/m(2)) was administered by intravenous drip on day 8. Partial response (PR) was obtained after the first course, and total gastrectomy was performed. The histological diagnosis revealed complete disappearance of cancer cells in the stomach and a few regional lymph node metastases (3/67). The patient has now been in good health without a recurrence for 1 year and 9 months after surgery.


Subject(s)
Adenocarcinoma, Scirrhous/drug therapy , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Gastrectomy , Lymph Nodes/pathology , Stomach Neoplasms/drug therapy , Adenocarcinoma, Scirrhous/secondary , Adenocarcinoma, Scirrhous/surgery , Aged , Cisplatin/administration & dosage , Drug Administration Schedule , Drug Combinations , Female , Humans , Lymphatic Metastasis , Neoadjuvant Therapy , Oxonic Acid/administration & dosage , Pyridines/administration & dosage , Remission Induction , Stomach Neoplasms/pathology , Stomach Neoplasms/surgery , Tegafur/administration & dosage
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