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1.
Antioxidants (Basel) ; 12(6)2023 Jun 11.
Article in English | MEDLINE | ID: mdl-37371988

ABSTRACT

This study investigates the role of eugenol (EUG) on CS-induced acute lung injury (ALI) and how this compound is able to modulate macrophage activity. C57BL/6 mice were exposed to 12 cigarettes/day/5days and treated 15 min/day/5days with EUG. Rat alveolar macrophages (RAMs) were exposed to CSE (5%) and treated with EUG. In vivo, EUG reduced morphological changes inflammatory cells, oxidative stress markers, while, in vitro, it induced balance in the oxidative stress and reduced the pro-inflammatory cytokine release while increasing the anti-inflammatory one. These results suggest that eugenol reduced CS-induced ALI and acted as a modulator of macrophage activity.

2.
Braz. j. microbiol ; 44(2): 465-468, 2013.
Article in English | LILACS, VETINDEX | ID: biblio-1469594

ABSTRACT

This study investigated biological characteristics of recovered stressed M. tuberculosis isolates that failed to grow in differential culture media for phenotypic identification and in culture media containing anti-tuberculosis drugs for drug-susceptibility testing, despite of having grown in primary culture. It represents an improvement in the diagnosis of MDR tuberculosis and tuberculosis control.


Subject(s)
Culture Media , Mycobacterium tuberculosis , Tuberculosis , Amplified Fragment Length Polymorphism Analysis , Colony Count, Microbial
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