Clock Drawing Test: A Simple Scoring System for the Accurate Screening of Cognitive Impairment in Patients with Mild Cognitive Impairment and Dementia.

BACKGROUND/AIM: The Clock Drawing Test (CDT) is a valid alternative screening tool to the Mini-Mental State Examination (MMSE) and, crucially, it may be completed faster. The aim of our study was to standardize and simplify the CDT scoring system for screening in three common conditions: mild cognitive impairment (MCI), Alzheimer's disease (AD) and mixed dementia (MD). METHODS: We included 188 subjects (43 healthy volunteers, 49 patients with MCI, 54 patients with AD, and 42 patients with MD), who performed the MMSE and CDT. The CDT was evaluated using a modified 4-point scoring system. RESULTS: The healthy subjects had the highest median values for the MMSE and CDT, followed by patients with MCI, AD and MD. The optimal cut-off for all patients and each patient group separately was 3 out of 4 points. Sensitivity was 89% for AD, 93% for MD and 83% for all patients, while specificity was 91%. The MMSE produced similar results. In comparison to the MMSE, sensitivity for MCI was significantly higher using the CDT (20 vs. 69%, respectively). CONCLUSION: A simple, 4-point scoring system may be used as a screening method for fast and accurate detection of cognitive impairment in patients with MCI, AD and MD.

Preliminary data on validity of the Drug Addiction Treatment Efficacy Questionnaire.

BACKGROUND: This study describes the validation process for the Slovenian version of the Drug Addiction Treatment Efficacy Questionnaire (DATEQ). SUBJECTS AND METHODS: DATEQ was constructed from the questionnaires used at the Centre for the Treatment of Drug Addiction, Ljubljana University Psychiatric Hospital, and within the network of Centres for the Prevention and Treatment of Drug Addiction in Slovenia during the past 14 years. The Slovenian version of the DATEQ was translated to English using the 'forward-backward' procedure by its authors and their co-workers. The validation process included 100 male and female patients with established addiction to illicit drugs who had been prescribed opioid substitution therapy. The DATEQ questionnaire was used in the study, together with clinical evaluation to measure psychological state and to evaluate the efficacy of treatment in the last year. To determinate the validity of DATEQ the correlation with the clinical assessments of the outcome was calculated using one-way ANOVA. RESULTS: The F value was 44.4, p<0.001 (sum of squares: between groups 210.4, df=2, within groups 229.7, df=97, total 440.1, df=99). At the cut-off 4 the sensitivity is 81% and specificity 83%. CONCLUSION: The validation process for the Slovenian DATEQ version shows metric properties similar to those found in international studies of similar questionnaires, suggesting that it measures the same constructs, in the same way and as similar questionnaires. However, the relatively low sensitivity and specificity suggests caution when using DATEQ as the only measure of outcome.

Validation of the Slovenian version of Hospital Anxiety and Depression Scale in female cancer patients.

INTRODUCTION: The present study describes the translation process of the Hospital Anxiety and Depression Scale (HADS) into the Slovenian language and the testing of its reliability and validity on the psychological morbidity in female cancer patients. SUBJECTS AND METHODS: The English version of the HADS was translated into the Slovene language using the 'forward-backward' procedure. The questionnaire was used in a study of 202 female cancer patients together with a clinical structured interview (CSI) to measure psychological state. A biserial correlation coefficient was calculated. RESULTS: The value of biserial correlation coefficient was 0.81 for the depression scale and 0.91 for the anxiety scale. CONCLUSION: The validation process of the Slovenian HADS score version shows metric properties similar to those in international studies, suggesting that it measures the same constructs, in the same way, as the original HADS score form. This validation study of the Slovenian version of the HADS proved that it is an acceptable and valid measure of psychological distress among female cancer patients.