ABSTRACT
OBJECTIVE: This study aims to evaluate the value of microbial rapid on-site evaluation (M-ROSE) of sepsis, and septic shock caused by pulmonary infection. PATIENTS AND METHODS: Thirty-six patients with sepsis and septic shock due to hospital-acquired pneumonia were analyzed. Accuracy and time were compared with M-ROSE, traditional culture, and next-generation sequencing (NGS). RESULTS: A total of 48 strains of bacteria and 8 strains of fungi were detected by bronchoscopy in 36 patients. The accuracy rate of bacteria and fungi was 95.8% and 100%, respectively. M-ROSE took an average of 0.34±0.01 hours, much faster than NGS (22h±0.01 h, p<0.0001) and traditional culture time (67.50±0.91 h, p<0.0001). CONCLUSIONS: M-ROSE may quickly identify common bacteria and fungi, so it may be a useful method for the etiological diagnosis of sepsis and septic shock caused by pulmonary infection.
Subject(s)
Pneumonia , Sepsis , Shock, Septic , Humans , Shock, Septic/microbiology , Rapid On-site Evaluation , Sepsis/diagnosis , Sepsis/microbiology , Pneumonia/diagnosis , Bacteria , Fungi , Retrospective StudiesABSTRACT
Respiratory support is a very important technique for saving severe 2019-nCoV pneumonia patients who suffering respiratory failure, which can improve oxygenation, reduce mortality. Therefore, how to reasonable using respiratory support technique is the key point that relating success or failure. In this paper, the authors introduce their experience on treating severe 2019-nCoV pneumonia, it is hopeful for current fighting against 2019-nCoV in China.
Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Pneumonia, Viral/drug therapy , Respiratory Distress Syndrome/therapy , Respiratory Insufficiency/therapy , COVID-19 , China , Humans , Pneumonia, Viral/complications , Pneumonia, Viral/etiology , Respiration, Artificial , Respiratory Distress Syndrome/virology , Respiratory Insufficiency/virology , SARS-CoV-2ABSTRACT
Respiratory support is a very important technique for saving severe 2019-nCoV pneumonia patients who suffering respiratory failure, which can improve oxygenation, reduce mortality. Therefore, how to reasonable using respiratory support technique is the key point that relating success or failure. In this paper, the authors introduce their experience on treating severe 2019-nCoV pneumonia, it is hopeful for current fighting against 2019-nCoV in China.
