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Rev Med Brux ; 27(1): 39-41, 2006.
Article in French | MEDLINE | ID: mdl-16608010

ABSTRACT

Hydroxyurea is an antitumour agent used most commonly to treat myeloproliferative disorders. We present a clinical observation illustrating different cutaneous side effects susceptible to occur during a long-term treatment by hydroxyurea : leg ulceration, oral ulcer and spinocellular carcinoma. This clinical observation is completed by a review of the literature published on the cutaneous side effects of hydroxyurea treatment.


Subject(s)
Antineoplastic Agents/adverse effects , Hydroxyurea/adverse effects , Leg Ulcer/chemically induced , Oral Ulcer/chemically induced , Aged , Antineoplastic Agents/therapeutic use , Carcinoma/chemically induced , Humans , Hydroxyurea/therapeutic use , Male , Myeloproliferative Disorders/drug therapy , Skin Neoplasms/chemically induced
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