1.
Bioorg Med Chem Lett
; 11(17): 2229-34, 2001 Sep 03.
Article
in English
| MEDLINE
| ID: mdl-11527704
ABSTRACT
A synthesis program directed toward improving the stability of imidoyl thiourea based non-nucleoside reverse transcriptase inhibitors (NNRTIs) led to the discovery of diaryltriazines (DATAs), a new class of potent NNRTIs. The synthesis and anti-HIV structure-activity relationship (SAR) studies of a series of DATA derivatives are described.
