1.
J Nucl Med
; 17(9): 805-9, 1976 Sep.
Article
in English
| MEDLINE
| ID: mdl-182933
ABSTRACT
Current techniques for determining the radiochemical purity of 99mTc-labeled radiopharmaceuticals are limited by the variety of compounds that can be tested or the length of time required to complete the test. A chromatographic method, based on the use of two solvents (0.9% saline and acetone) and a stationary phase made of silica-coated cellulose strips, solves these problems for water-soluble 99mTc-labeled radiopharmaceuticals. With this method, the oxidation state of unbound 99mTc and the labeling yield of 99mTc-labeled radiopharmaceuticals can be quickly determined: the whole procedure takes only a few minutes to run. This system compares favorably with lengthier procedures and with a commercially available kit.
Subject(s)
Technetium , Chromatography/methods , Diphosphates , Isotope Labeling , Pentetic Acid , Quality Control
2.
Int J Nucl Med Biol
; 2(4): 180-4, 1975 Oct.
Article
in English
| MEDLINE
| ID: mdl-1205665