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1.
J Oral Maxillofac Surg ; 79(12): 2593-2602, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34391723

ABSTRACT

PURPOSE: Large scalp defects pose a reconstructive problem especially in elderly patients. The purpose of the study is to describe our experience of oncologic scalp reconstruction using a dermal matrix (Integra). MATERIAL AND METHODS: We conducted a retrospective cohort study (January 2007 to March 2021) of patients who had undergone scalp tumor excision and reconstruction using Integra and a split-thickness skin graft (STSG). The primary end point was Integra and STSG success (defined by ≥75% percent take) and the secondary end point was postoperative complications. Both end points were assessed by the surgeon during follow-up. Demographic data, tumor characteristics, average defect size, time between stages and full-thickness scalp defects were characterized using descriptive statistics. Univariate and multivariate logistic regression models were used to evaluate the association between variables and end points. RESULTS: The sample included 70 patients with a mean (SD) age of 83.3 (7.0) years, 75.7% men and 92.9% with comorbidities. Mean (SD) defect area was 23 (17.0) cm2 and the mean (SD) first-to-second phase interval was 30.6 (8.4) days. Sixty-four patients (91.4%) underwent outpatient surgery. Integra and STSG success rates were 87.1% (95% CI: 77.69 to 93.74%) and 100%, respectively. The complications rate was 18.6% (95% CI: 9 to 28%). Mean (SD) follow-up was 18 (16.7) months. Univariate and multivariate logistic regression analysis showed no association between variables and the primary and secondary end points. CONCLUSIONS: Reconstruction of oncologic scalp defects using Integra can be performed under sedation and local anesthesia. Integra should be considered as firstline treatment for the reconstruction of scalp defects in elderly patients with comorbidities, given the low postoperative major complications rate and Integra and STSG take success.


Subject(s)
Plastic Surgery Procedures , Scalp , Aged , Aged, 80 and over , Chondroitin Sulfates , Collagen , Female , Humans , Male , Retrospective Studies , Scalp/surgery , Skin Transplantation
4.
J Craniomaxillofac Surg ; 44(4): 331-6, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26920045

ABSTRACT

We conducted a systematic review of the literature to evaluate treatment of oral leukoplakia with the carbon dioxide (CO2) laser. A comprehensive search of studies published between 1981 and 2015 and listed in the PubMed (National Library of Medicine, NCBI) database yielded 378 articles which were screened in detail. Relevant studies were selected according to predetermined inclusion and exclusion criteria. A total of 33 articles met the final inclusion criteria and were analysed in detail in accordance with the PRISMA-P statement. These full-text papers were classified as synopses (n = 7), recurrence and malignant transformation studies (n = 17), comparative studies between CO2 laser and cold knife surgery (n = 3) and studies evaluating the efficacy of CO2, Nd:YAG and KTP lasers. According to the literature the CO2 laser is the workhorse of oral leukoplakia treatment due to its effectiveness and low associated morbidity. However, randomized clinical trials are needed to compare CO2 laser with other lasers. The results of our systematic review showed that there is no consensus regarding the factors involved in higher recurrence and malignization rates, so further studies are needed.


Subject(s)
Lasers, Gas/therapeutic use , Leukoplakia, Oral/surgery , Neoplasm Recurrence, Local/surgery , Humans , Laser Therapy , Lasers, Solid-State/therapeutic use
7.
J Craniomaxillofac Surg ; 43(5): 677-81, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25913630

ABSTRACT

The use of CO2 laser has become a routine procedure for the treatment of oral leukoplakia. In this retrospective study, we evaluated 65 patients with oral leukoplakia treated with CO2 laser vaporization. The main location was the tongue (n = 21/65, 32.3%). The initial biopsy showed mild/moderate dysplasia in almost half the patients (n = 29, 44.6%) and hyperplasia without dysplasia in around a third of the patients (n = 21, 32.3%). The recurrence and malignant transformation rates were 33.8% (n = 22) and 15.4% (n = 10), respectively. The follow-up mean (standard deviation) was 15.0 (10.6) months. The procedure-related complications rate was 7.7% (n = 5). The Kaplan-Meier curves for time to recurrence showed differences only for gingiva lesions compared to tongue lesions (log rank, p = 0.032). Malignant leukoplakia transformation is independent of treatment, although it seems advisable to treat leukoplakia with or without dysplasia.


Subject(s)
Laser Therapy/methods , Lasers, Gas/therapeutic use , Leukoplakia, Oral/surgery , Aged , Carcinoma, Squamous Cell/pathology , Cell Transformation, Neoplastic/pathology , Cohort Studies , Female , Follow-Up Studies , Gingival Neoplasms/pathology , Gingival Neoplasms/surgery , Humans , Hyperplasia , Leukoplakia, Oral/pathology , Male , Middle Aged , Neoplasm Recurrence, Local/pathology , Postoperative Complications , Retrospective Studies , Tongue Neoplasms/surgery
8.
Rev. esp. cir. oral maxilofac ; 36(4): 164-168, oct.-dic. 2014.
Article in Spanish | IBECS | ID: ibc-129862

ABSTRACT

Introducción. El manejo de la vía aérea en cirugía de cabeza y cuello presenta varios retos tanto para el cirujano como para el anestesista. El empleo de la traqueostomía electiva es ampliamente usado pero continúan existiendo algunas controversias en la literatura al respecto. Material y métodos. Se ha realizado un estudio prospectivo analizando aspectos clínicos, indicaciones y complicaciones en 57 pacientes afectados de enfermedad oncológica de cabeza y cuello que requirieron la realización de una traqueostomía durante el período comprendido entre enero de 2011 y junio de 2012 en el servicio de cirugía oral y maxilofacial del Hospital Universitario Vall d́Hebron de Barcelona. Resultados. El grupo de pacientes que recibieron una reconstrucción microquirúgica fue el mayoritario que requirió una traqueostomía (40,35%). La tasa de complicaciones asociada con la técnica fue del 22,8%, de las cuales el 7% fueron consideradas mayores y 5,8% menores. La tasa de complicaciones asociadas con los cuidados de la cánula fue del 15,8%. Conclusiones. La traqueostomía es un método simple y efectivo para el manejo de la vía aérea difícil en pacientes oncológicos de cabeza y cuello asociada a una baja tasa de complicaciones (AU)


Background. Airway management in head and neck surgery presents several challenges to the surgeon and the anaesthesist. The use of elective tracheostomy is widely used, but there is still some controversy in the literature. Methods. A prospective study analyzing clinical aspects, indications and complications of 57 head and neck patients who underwent tracheostomy was performed from January 2011 to June 2012 in the Oral and Maxillofacial Surgery Department of Vall D́Hebron Hospital, Barcelona, Spain. Results. Microvascular reconstruction patients were the most frequent group in which tracheostomy was performed (40.35%). The complications rate associated with the technique was of 22.8%, of which only 7% were considered major, and 5.8% minor. The complication rate in relation to cannula care was 15.8%. Conclusions. We conclude that tracheostomy is a simple and effective method for airway management in head and neck patients, with a low complication rate (AU)


Subject(s)
Humans , Male , Female , Airway Management/instrumentation , Airway Management/methods , Airway Management , Tracheostomy/methods , Tracheostomy/trends , Head and Neck Neoplasms/epidemiology , Airway Management/statistics & numerical data , Airway Management/trends , Prospective Studies , Risk Factors , Oral Surgical Procedures/methods , Oral Surgical Procedures/trends
9.
Rev. esp. cir. oral maxilofac ; 36(4): 182-87, oct.-dic. 2014.
Article in Spanish | IBECS | ID: ibc-129866

ABSTRACT

El estesioneuroblastoma es un tumor maligno de la mucosa olfatoria localizado en el tracto nasosinusal con un manejo controvertido debido a su baja incidencia y a su origen desconocido. La resección craneofacial, empleando un abordaje subfrontal, es uno de los abordajes de elección para el tratamiento de esta compleja entidad. Describimos un caso tratado en nuestra institución que fue resuelto favorablemente con este procedimiento, así como una revisión exhaustiva de la bibliografía con respecto a este tipo de tumor y a las ventajas de este abordaje (AU)


Esthesioneuroblastoma is a rare malignant tumor of the olfactory mucosa located in the sinonasal tract with a controversial management due to its low incidence and unknown origin. Craniofacial resection using a subfrontal approach is one of the techniques of choice for treating this complex entity. We describe a case treated in our institution that responded favorably to this procedure, as well as a thorough review of the literature regarding this type of tumor and the advantages of the approach (AU)


Subject(s)
Humans , Female , Adult , Neuroblastoma/complications , Neuroblastoma/surgery , Neuroblastoma , Esthesioneuroblastoma, Olfactory/complications , Esthesioneuroblastoma, Olfactory/surgery , Esthesioneuroblastoma, Olfactory , Esthesioneuroblastoma, Olfactory/physiopathology , Skull Base/pathology , Skull Base/surgery , Skull Base , Olfactory Mucosa/pathology , Olfactory Mucosa/surgery , Olfactory Mucosa
10.
Article in English | MEDLINE | ID: mdl-24618057

ABSTRACT

Immunoglobulin G4-related disease is a recently identified entity. The cervicofacial location is not frequent. We report the case of a patient with an inflammatory pseudotumor in the mandible, who had to undergo surgery for diagnosis. We review the clinical manifestations, diagnostic criteria, differential diagnosis, and treatment proposed by recent publications in the literature. This case report represents the first case located in the mandible and the second one with bone destruction.


Subject(s)
Autoimmune Diseases/diagnosis , Autoimmune Diseases/surgery , Granuloma, Plasma Cell/diagnosis , Granuloma, Plasma Cell/surgery , Immunoglobulin G/blood , Mandibular Diseases/diagnosis , Mandibular Diseases/surgery , Adult , Autoimmune Diseases/pathology , Biopsy , Diagnosis, Differential , Granuloma, Plasma Cell/pathology , Humans , Imaging, Three-Dimensional , Magnetic Resonance Imaging , Male , Mandibular Diseases/pathology , Tomography, X-Ray Computed
11.
Rev. esp. cir. oral maxilofac ; 35(2): 83-86, abr.-jun. 2013.
Article in Spanish | IBECS | ID: ibc-112139

ABSTRACT

En la literatura indexada, solo se han descrito 29 pacientes desde 1986. La aparición de metástasis de un carcinoma renal a nivel parotídeo es un fenómeno poco frecuente. Presentamos un paciente de 61 años, que tras cinco años de la realización de una nefrectomía unilateral por un carcinoma renal de células claras, desarrolló una metástasis de localización parotídea(AU)


Metastastic spread of renal cell carcinoma to the parotid gland is rare. In the indexed literature, with only 29 patients recorded since 1986. The case of a 61-year-old patient who developed parotid metastasis of renal cell carcinoma five years after unilateral nephrectomy is reported(AU)


Subject(s)
Humans , Male , Middle Aged , Carcinoma, Renal Cell/complications , Carcinoma, Renal Cell/diagnosis , Parotid Region/pathology , Parotid Region/surgery , Parotid Region , Salivary Glands/pathology , Salivary Glands/surgery , Interferons/therapeutic use , Neoplasm Metastasis/pathology , Neoplasm Metastasis , Carcinoma, Renal Cell/physiopathology , Salivary Glands/physiopathology , Magnetic Resonance Spectroscopy/methods , Magnetic Resonance Imaging
12.
Rev. esp. cir. oral maxilofac ; 34(3): 105-110, jul.-sept. 2012.
Article in Spanish | IBECS | ID: ibc-102427

ABSTRACT

Introducción: Los sarcomas mandibulares representan una entidad de difícil estudio por su escasa incidencia e histopatología. Pacientes y métodos: Presentamos la experiencia del servicio de Cirugía Oral y Maxilofacial del Hospital Vall d’Hebron de Barcelona en los últimos 10 años (2001-2010) en el manejo de los sarcomas mandibulares, realizando una revisión retrospectiva de 12 casos de pacientes afectos por este tipo de tumor. Resultados: La técnica más utilizada para la reconstrucción fue el colgajo microvascularizado (hueso peroné: 8/12), recibiendo tratamiento adyuvante (quimioterapia y/o radioterapia) el 82% de los pacientes. Cinco pacientes fallecieron (42%), 2 se encuentran con progresión de la enfermedad (16%) y 5 sobreviven libres de enfermedad (42%) hasta la finalización del seguimiento. Conclusiones: Los casos descritos representan una serie singular debido a la localización mandibular, no antes publicadas en la literatura. Aún así, los resultados obtenidos en términos de supervivencia y factores pronóstico son similares a los descritos para los sarcomas de cabeza y cuello. La consecución de márgenes libres con la cirugía es la clave del tratamiento, siendo necesario el tratamiento complementario para mejorar el pronóstico(AU)


Introduction: Sarcomas located in the mandible are difficult to study due to their relatively rare appearance and histology. Patients and Methods: We present the experience of the Oral and Maxillofacial Surgery Department of the Vall d’Hebron Hospital in Barcelona over the last 10 years (2001-2010) in the management of jaw sarcomas, performing a retrospective review of 12 cases of patients affected by this type of tumour. Results: The technique mostly used for the reconstruction was the microvascularised bone graft (fibula: 8/12), with 82% of the patients receiving adjuvant therapy (chemotherapy and radiotherapy). Five of the patients died (42%), twowere found with disease progression (16%), and 5 survived free of disease (42%) until the end of follow-up. Conclusions: The cases described are a unique series due to the mandibular location. Prognostic factors and survival rates are similar to those described for head and neck sarcomas. Free margin during surgery must be the goal of treatment, additional chemotherapy or radiotherapy or both being required to improve the survival rates(AU)


Subject(s)
Humans , Male , Adult , Sarcoma/complications , Sarcoma/diagnosis , Sarcoma/surgery , Surgery, Oral/methods , Surgery, Oral , Surgical Flaps , Mandibular Neoplasms/surgery , Chondrosarcoma/surgery , Chondrosarcoma , Sarcoma/physiopathology , Sarcoma , Chemotherapy, Adjuvant/methods , Chemotherapy, Adjuvant , Radiotherapy, Adjuvant
13.
Rev. esp. cir. oral maxilofac ; 34(3): 118-121, jul.-sept. 2012. ilus
Article in Spanish | IBECS | ID: ibc-102429

ABSTRACT

Los lipomas son los tumores mesenquimales más frecuentes. La aparición de lipomas gigantes a nivel cervical es infrecuente. Es necesaria la realización de pruebas de imagen para una correcta localización anatómica y establecer relaciones con las estructuras vecinas. El tratamiento de elección es la escisión quirúrgica de la masa. Presentamos el caso de un varón de 59 años que presenta una tumoración gigante cervical de 10 años de evolución. La planificación prequirúrgica en este tipo de casos debe ser exquisita para garantizar la conservación tanto de la función como de la estética cervicofacial(AU)


Lipomas are the most common mesenchymal tumors, although giant lipomas of the neck region are uncommon. Imaging is needed to correctly identify the anatomic location of the tumor and its relation to surrounding structures. Surgical excision is the treatment of choice. The case of a 59-year-old man with a giant neck tumor of 10 years evolution is reviewed. Meticulous preoperative planning is required in these cases to ensure a cosmetically and functionally acceptable cervicofacial outcome(AU)


Subject(s)
Humans , Male , Middle Aged , Lipoma/diagnosis , Lipoma/surgery , Lipomatosis, Multiple Symmetrical/complications , Lipomatosis, Multiple Symmetrical/diagnosis , Lipomatosis, Multiple Symmetrical/surgery , Magnetic Resonance Imaging/methods , Lipoma/physiopathology , Lipoma , Mesenchymal Stem Cells/pathology , Mesenchymal Stem Cells , Lipomatosis, Multiple Symmetrical/physiopathology , Lipomatosis, Multiple Symmetrical
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