ABSTRACT
Background: Charcoal in the composition of some kinds of toothpaste has created concerns regarding abrasiveness and subsequent complications. Considering the popularity of charcoal toothpaste, and the manufacturers' claims that no porosity is caused by activated carbon, this study aimed to compare the effects of two charcoal kinds of toothpaste and three conventional tubes of toothpaste on enamel surface roughness of permanent primary teeth. Materials and Methods: This in vitro experimental study evaluated 75 teeth mounted in acrylic resin. Teeth were divided into five groups (n = 15). The primary surface roughness of teeth was measured by a profilometer. The teeth were then subjected to wear test in a V8 cross-brushing machine with Bencer and RP charcoal toothpaste, Crest 7, Colgate Optic White, and Bencer fresh mint toothpaste. After rinsing and drying specimens, their secondary surface roughness was measured. The mean changes in the roughness profile of specimens were analyzed by a one-sample Kolmogorov-Smirnov test at a 0.05 significance level. Results: There was no significant difference in the mean surface roughness of specimens before and after the wear test (P > 0.05). The difference in the mean wear of five types of toothpaste was not significant either (P = 0.597). The mean changes in surface roughness were 0.0685 µm for Bencer charcoal, -0.0620 µm for RP charcoal, 0.0765 µm for Crest 7, 0.1137 µm for Colgate Optic White, and 0.1052 µm for Bencer fresh mint toothpaste. Conclusion: Numerous kinds of toothpaste investigated in this study did not reveal any difference in terms of wear index; however, more studies are needed to evaluate the effectiveness and efficiency of these types of toothpaste.
ABSTRACT
Background: Plant compounds such as Aloe vera, green tea, and chamomile have been increasingly used in recent years to achieve oral health. This study aimed to determine the antimicrobial effect of chamomile (Matrika), A. vera-green tea, and chlorhexidine (CHX) mouthwashes on some oral bacterial species. Materials and Methods: This prospective experimental study investigated the antimicrobial properties of three mouthwashes, including chamomile (Matrika), A. vera -green tea, and CHX as well as distilled water as control on five bacterial species, including Streptococcus Oralis, Streptococcus sanguis, and Streptococcus mutans as primary colonizers and Porphyromonas gingivalis and Eikenella corrodens as secondary colonizers. Colony-forming unit was used to count the colonies and disc diffusion and well diffusion methods were used to measure the diameter of zone of inhibition. Data were analyzed by SPSS (version 22) software using descriptive statistics, ANOVA, Tukey, Kruskal-Wallis, and Mann-Whitney tests (α = 0.05). Results: CHX had a significantly higher antibacterial effect than the other two mouthwashes in all three methods (P < 0.001). Further, the herbal mouthwashes in all three methods had a statistically significant effect on the bacterial species (P < 0.001). A. vera-green tea mouthwash had a significantly higher effect than chamomile mouthwash (Matrika) on all bacterial species except for S. sanguis (P < 0.05). Conclusion: The findings showed that herbal mouthwashes had potentially antibacterial effects, but these effects were significantly lower than that of CHX. However, more clinical studies are needed to prove the current findings.
ABSTRACT
BACKGROUND: Low-level laser therapy (LLLT) has shown a promising effect in ameliorating symptoms of rheumatoid arthritis (RA). The aim of this investigation was to compare the early and late anti-inflammatory effects of LLLT and betamethasone in RA. MATERIALS AND METHODS: In this animal experimental study, after inducing a model of RA in temporomandibular joint (TMJ) of 37 Wistar rats using adjuvant injection, they were randomly distributed into three experimental groups of 12 animals each: (1) LLLT group; (2) steroid group which received a single dose of betamethasone systemically; and (3) positive control group, which did not receive any treatment. One rat served as the negative control. Half of the animals in all the experimental groups were sacrificed on the 21(st) day after RA induction (early phase), and the other half were sacrificed 2 weeks later (late phase). Then, the severity of TMJ inflammation was assessed histologically in each group on a semi-quantitative scale. Kruskal-Wallis and Mann-Whitney tests were used to compare differences (α = 0.05). RESULTS: The LLLT and steroid groups showed significantly (P < 0.05) lower inflammation mean scores in both early (5.66 [±1.86] and 1.66 [±1.21], respectively) and late phases of evaluation (1.16 [±1.47] and 6.50 [±1.04], respectively) compared to positive control group in early and late stages of assessment (11.66 [±3.50] and 8.66 [±1.36], respectively). However, the best results (P < 0.005) were achieved in early phase of the steroid group as well as late phase of the LLLT group. CONCLUSION: Within limitations of this study, it may be concluded that LLLT method has a long-term promising effect on reducing inflammation severity of TMJ similar to betamethasone in earlier stages.
ABSTRACT
BACKGROUND: Different methods have been suggested to preserve bone architecture following traumatic events such as teeth extraction. The purpose of the study was to histologically and histomorphometrically evaluate the dental socket healing after applying porous titanium granules (PTG) in dogs. MATERIALS AND METHODS: Four healthy male dogs were involved in the present 6-weeks experimental animal study. Three sockets were surgically created in each side of dog's mandible. One of the sockets in one side was randomly filled by PTG and covered by a resorbable membrane (Tigran + membrane group). Another socket was left unfilled and just covered by the same membrane (membrane group) and the last one was left unfilled and uncovered as the control group. The dogs were killed at two time intervals (2 weeks and 6 weeks, two dogs at each time point). All samples were histologically evaluated under an optical microscope for a new bone formation. Data were analyzed by SPSS ver. 16 and Kruskal-Wallis and Mann-Whitney tests were used to compare data in different groups (α = 0.05). RESULTS: There was a significant difference between the Tigran + membrane and the control group in 2 and 6 weeks in the mean amount of total regenerated bone (P < 0.05). The mean amounts of woven, lamellar, and total regenerated bone showed significant differences between 2 weeks and 6 weeks for all three groups (P < 0.05). CONCLUSIONS: It can be assumed that the use of Tigran bone substitute with membrane can promote the bone regeneration in bone defects.
