ABSTRACT
Posttherapy scan in a 21-year-old woman with papillary carcinoma of thyroid with lymph node metastasis, who received 5.55 GBq of radioiodine (I), revealed halo-like diffuse tracer uptake in the pericardial region. Echocardiography showed no abnormality except pericardial effusion, which subsided after reinstitution of levothyroxine therapy. Although rare, false-positive radioiodine uptake can occur in pericardial effusion secondary to thyroxine withdrawal-related hypothyroidism and needs close monitoring of the patient.
Subject(s)
Iodine Radioisotopes/pharmacokinetics , Pericardial Effusion/diagnostic imaging , Radiopharmaceuticals/pharmacokinetics , Carcinoma, Papillary/diagnostic imaging , Carcinoma, Papillary/metabolism , False Positive Reactions , Female , Humans , Hypothyroidism/complications , Pericardial Effusion/metabolism , Radionuclide Imaging/methods , Thyroid Neoplasms/diagnostic imaging , Young AdultSubject(s)
Dideoxynucleosides , Fluorodeoxyglucose F18 , Hamartoma/diagnostic imaging , Hamartoma/pathology , Positron-Emission Tomography/methods , Solitary Pulmonary Nodule/diagnostic imaging , Solitary Pulmonary Nodule/pathology , Diagnosis, Differential , Female , Humans , Lung Diseases/diagnostic imaging , Lung Diseases/pathology , Lung Neoplasms/diagnostic imaging , Middle Aged , Radioactive Tracers , RadiopharmaceuticalsSubject(s)
Kidney Diseases/etiology , Neuroectodermal Tumors, Primitive/complications , Radiopharmaceuticals , Splenic Neoplasms/pathology , Technetium Tc 99m Pentetate , Thoracic Vertebrae/pathology , Diagnosis, Differential , Glomerular Filtration Rate , Humans , Kidney Diseases/diagnosis , Male , Neuroectodermal Tumors, Primitive/diagnosis , Prognosis , Splenic Neoplasms/drug therapyABSTRACT
A rare case of osteogenic sarcoma (OGS) of the left humerus metastasizing to the right breast is presented. This lesion was detected by serendipitous observation on (99m)Tc-MDP skeletal scintigraphy that demonstrated a rounded focus just outside the skeletal outline of the right chest. The focus remained at a similar location on repeat postwash view. Clinical examination revealed a breast mass corresponding to the site of uptake, and a biopsy of this mass revealed it to be a metastasis of osteogenic sarcoma. The present case demonstrates a rare site of metastasis from OGS of the left humerus to the contralateral breast and hence is reported here as an unusual case vignette.