1.
Chem Commun (Camb)
; 48(3): 431-3, 2012 Jan 11.
Article
in English
| MEDLINE
| ID: mdl-22075973
ABSTRACT
A conceptually new three-component reaction was developed to construct a six-membered fused N-heterocyclic ring affording (pyrazolo)pyrimidines/pyridines as potential inhibitors of PDE4. The reaction is catalyzed by triflic acid in acetic acid in the presence of aerial oxygen.