ABSTRACT
BACKGROUND: The existing studies have indicated that persons with positive attitude and believe to narcotics have more addiction than those with negative or natural attitudes. The aim of the present study was to specify the effectiveness of cognitive-behavioral training on increasing of self-concept's measure, and the attitude style toward narcotic drugs in addicted prisoners of Tonekabon. OBJECTIVES: The objective of this study was to assess the effects of cognitive-behavioral training on increasing self-concept and the attitude style toward narcotic drugs. PATIENTS AND METHODS: Statistical population included 450 persons. After screening, 65 entered the study. Among them, 40 persons were selected randomly and allocated in experimental and control group. Self-concept and gauge attitude questionnaire were used to gather the data. The program of cognitive-behavioral training was executed at 12 weekly sessions in 120 minutes for experimental group. The past-quest was executed after finishing training for two groups. RESULTS: The result using analysis of covariance showed that the difference between two groups on self-concept and the attitude toward narcotic drugs was significant at P < 0.5. CONCLUSIONS: Therefore it can be resulted that cognitive-behavioral training is effective on self-concept and the changing of attitude toward narcotic drugs.
ABSTRACT
BACKGROUND: Mental retardation/Developmental delay (MR/DD) is present in 1 - 3% of the general population (1, 2). MR is defined as a significant impairment of both cognitive (IQ < 70) and social adaptive functions, with onset before 18 years of age. OBJECTIVES: The purpose was to determine the results of subtelomeric screening by the Multiplex Ligation Dependent Probe Amplification (MLPA) Technique in 100 selected patients with idiopathic mental retardation (IMR) in Iran. MATERIALS AND METHODS: A number of 100 patients with IMR, normal karyotypes and negative fragile-X and metabolic tests were screened for subtelomeric abnormalities using MLPA technique. RESULTS: Nine of 100 patients showed subtelomeric abnormalities with at least one of the two MLPA kits. Deletion in a single region was found in 3 patients, and in two different subtelomeric regions in 1 patient. Duplication was only single and was present in 2 patients. Three patients were found to have both a deletion and duplication.MLPA testing in the parental samples of 7 patients which was accessible showed that 4 patients were de novo, 2 patients had inherited from a clinically normal mother, and one had inherited from a clinically normal father. Screening with the two MLPA kits (SALSA P036 and SALSA P070) proved abnormality in only five of the 9 patients. CONCLUSIONS: So, the prevalence rate of abnormal subtelomeres using MLPA technique in patients with idiopathic MR in our study was 5 - 9%, the higher limit referring to the positive results of one of the two MLPA kits, and the lower limit representing the results of positive double-checking with the two MLPA kits.
