Comparing Different Donor Sites After Vascularized Lymph Node Transfer to the Lymphedematous Upper Limb: A Systematic Review and Meta-analysis of Clinical Outcomes.

BACKGROUND: Vascularized lymph node transfer (VLNT) involves the microvascular transplantation of functional lymph nodes from a donor site into a limb affected by lymphedema to restore the normal flow of lymphatic fluid. Despite the increasing clinical experience with VLNT, there remains insufficient data to support its routine use in clinical practice. Here, we aim to evaluate the effectiveness and safety of VLNTs for upper limb lymphedema and compare clinical outcomes when using different donor sites. METHODS: We carried out a systematic search of the literature through PubMed and Scopus databases for studies on VLNT for upper limb lymphedema. Primary and secondary outcomes included circumference reduction rate (CRR) and infection reduction rate by postoperative cellulitis episodes for the efficacy and safety of VLNT. Pooled analysis was performed using the inverse variance weighting meta-analysis of single means using the meta package in R software. Subgroup analyses were performed for donor and recipient sites, age groups, follow-ups, and symptom durations. Quality assessment was performed using the Newcastle-Ottawa Scale for nonrandomized studies. RESULTS: A total of 1089 studies were retrieved from the literature, and 15 studies with 448 upper limb lymphedema patients who underwent VLNT were included after eligibility assessment. The mean CRR was 34.6 (18.8) and the mean postoperative cellulitis episodes per year was 0.71 (0.7). The pooled analysis of CRR was 28.4% (95% confidence interval, 19.7-41.1) and postoperative cellulitis episodes showed a mean of 0.59 (95% confidence interval, 0.36-0.95) using the random-effect model. Subgroup analyses showed significant group differences in recipient site for CRR and postoperative cellulitis episodes with the wrist comprising the highest weights, and patients younger than 50 years showing a lower postoperative infection. CONCLUSIONS: Vascularized lymph node transfer using gastroepiploic flaps at the wrists has shown a significant difference in reductions of limb circumference and cellulitis episodes in upper limb lymphedema patients when compared with other donor sites. However, further prospective studies are needed to consolidate this finding.

Fiber-optics IoT healthcare system based on deep reinforcement learning combinatorial constraint scheduling for hybrid telemedicine applications.

Telemedicine is an emerging development in the healthcare domain, where the Internet of Things (IoT) fiber optics technology assists telemedicine applications to improve overall digital healthcare performances for society. Telemedicine applications are bowel disease monitoring based on fiber optics laser endoscopy, gastrointestinal disease fiber optics lights, remote doctor-patient communication, and remote surgeries. However, many existing systems are not effective and their approaches based on deep reinforcement learning have not obtained optimal results. This paper presents the fiber optics IoT healthcare system based on deep reinforcement learning combinatorial constraint scheduling for hybrid telemedicine applications. In the proposed system, we propose the adaptive security deep q-learning network (ASDQN) algorithm methodology to execute all telemedicine applications under their given quality of services (deadline, latency, security, and resources) constraints. For the problem solution, we have exploited different fiber optics endoscopy datasets with images, video, and numeric data for telemedicine applications. The objective is to minimize the overall latency of telemedicine applications (e.g., local, communication, and edge nodes) and maximize the overall rewards during offloading and scheduling on different nodes. The simulation results show that ASDQN outperforms all telemedicine applications with their QoS and objectives compared to existing state action reward state (SARSA) and deep q-learning network (DQN) policy during execution and scheduling on different nodes.

Digital healthcare framework for patients with disabilities based on deep federated learning schemes.

Utilizing digital healthcare services for patients who use wheelchairs is a vital and effective means to enhance their healthcare. Digital healthcare integrates various healthcare facilities, including local laboratories and centralized hospitals, to provide healthcare services for individuals in wheelchairs. In digital healthcare, the Internet of Medical Things (IoMT) allows local wheelchairs to connect with remote digital healthcare services and generate sensors from wheelchairs to monitor and process healthcare. Recently, it has been observed that wheelchair patients, when older than thirty, suffer from high blood pressure, heart disease, body glucose, and others due to less activity because of their disabilities. However, existing wheelchair IoMT applications are straightforward and do not consider the healthcare of wheelchair patients with their diseases during their disabilities. This paper presents a novel digital healthcare framework for patients with disabilities based on deep-federated learning schemes. In the proposed framework, we offer the federated learning deep convolutional neural network schemes (FL-DCNNS) that consist of different sub-schemes. The offloading scheme collects the sensors from integrated wheelchair bio-sensors as smartwatches such as blood pressure, heartbeat, body glucose, and oxygen. The smartwatches worked with wearable devices for disabled patients in our framework. We present the federated learning-enabled laboratories for data training and share the updated weights with the data security to the centralized node for decision and prediction. We present the decision forest for centralized healthcare nodes to decide on aggregation with the different constraints: cost, energy, time, and accuracy. We implemented a deep CNN scheme in each laboratory to train and validate the model locally on the node with the consideration of resources. Simulation results show that FL-DCNNS obtained the optimal results on the sensor data and minimized the energy by 25%, time 19%, cost 28%, and improved the accuracy of disease prediction by 99% as compared to existing digital healthcare schemes for wheelchair patients.

Multi-objectives reinforcement federated learning blockchain enabled Internet of things and Fog-Cloud infrastructure for transport data.

For the past decade, there has been a significant increase in customer usage of public transport applications in smart cities. These applications rely on various services, such as communication and computation, provided by additional nodes within the smart city environment. However, these services are delivered by a diverse range of cloud computing-based servers that are widely spread and heterogeneous, leading to cybersecurity becoming a crucial challenge among these servers. Numerous machine-learning approaches have been proposed in the literature to address the cybersecurity challenges in heterogeneous transport applications within smart cities. However, the centralized security and scheduling strategies suggested so far have yet to produce optimal results for transport applications. This work aims to present a secure decentralized infrastructure for transporting data in fog cloud networks. This paper introduces Multi-Objectives Reinforcement Federated Learning Blockchain (MORFLB) for Transport Infrastructure. MORFLB aims to minimize processing and transfer delays while maximizing long-term rewards by identifying known and unknown attacks on remote sensing data in-vehicle applications. MORFLB incorporates multi-agent policies, proof-of-work hashing validation, and decentralized deep neural network training to achieve minimal processing and transfer delays. It comprises vehicle applications, decentralized fog, and cloud nodes based on blockchain reinforcement federated learning, which improves rewards through trial and error. The study formulates a combinatorial problem that minimizes and maximizes various factors for vehicle applications. The experimental results demonstrate that MORFLB effectively reduces processing and transfer delays while maximizing rewards compared to existing studies. It provides a promising solution to address the cybersecurity challenges in intelligent transport applications within smart cities. In conclusion, this paper presents MORFLB, a combination of different schemes that ensure the execution of transport data under their constraints and achieve optimal results with the suggested decentralized infrastructure based on blockchain technology.

Autism Spectrum Disorder detection framework for children based on federated learning integrated CNN-LSTM.

The incidence of Autism Spectrum Disorder (ASD) among children, attributed to genetics and environmental factors, has been increasing daily. ASD is a non-curable neurodevelopmental disorder that affects children's communication, behavior, social interaction, and learning skills. While machine learning has been employed for ASD detection in children, existing ASD frameworks offer limited services to monitor and improve the health of ASD patients. This paper presents a complex and efficient ASD framework with comprehensive services to enhance the results of existing ASD frameworks. Our proposed approach is the Federated Learning-enabled CNN-LSTM (FCNN-LSTM) scheme, designed for ASD detection in children using multimodal datasets. The ASD framework is built in a distributed computing environment where different ASD laboratories are connected to the central hospital. The FCNN-LSTM scheme enables local laboratories to train and validate different datasets, including Ages and Stages Questionnaires (ASQ), Facial Communication and Symbolic Behavior Scales (CSBS) Dataset, Parents Evaluate Developmental Status (PEDS), Modified Checklist for Autism in Toddlers (M-CHAT), and Screening Tool for Autism in Toddlers and Children (STAT) datasets, on different computing laboratories. To ensure the security of patient data, we have implemented a security mechanism based on advanced standard encryption (AES) within the federated learning environment. This mechanism allows all laboratories to offload and download data securely. We integrate all trained datasets into the aggregated nodes and make the final decision for ASD patients based on the decision process tree. Additionally, we have designed various Internet of Things (IoT) applications to improve the efficiency of ASD patients and achieve more optimal learning results. Simulation results demonstrate that our proposed framework achieves an ASD detection accuracy of approximately 99% compared to all existing ASD frameworks.

Industrial Internet of Water Things architecture for data standarization based on blockchain and digital twin technology☆.

INTRODUCTION: The Industrial Internet of Water Things (IIoWT) has recently emerged as a leading architecture for efficient water distribution in smart cities. Its primary purpose is to ensure high-quality drinking water for various institutions and households. However, existing IIoWT architecture has many challenges. One of the paramount challenges in achieving data standardization and data fusion across multiple monitoring institutions responsible for assessing water quality and quantity. OBJECTIVE: This paper introduces the Industrial Internet of Water Things System for Data Standardization based on Blockchain and Digital Twin Technology. The main objective of this study is to design a new IIoWT architecture where data standardization, interoperability, and data security among different water institutions must be met. METHODS: We devise the digital twin-enabled cross-platform environment using the Message Queuing Telemetry Transport (MQTT) protocol to achieve seamless interoperability in heterogeneous computing. In water management, we encounter different types of data from various sensors. Therefore, we propose a CNN-LSTM and blockchain data transactional (BCDT) scheme for processing valid data across different nodes. RESULTS: Through simulation results, we demonstrate that the proposed IIoWT architecture significantly reduces processing time while improving the accuracy of data standardization within the water distribution management system. CONCLUSION: Overall, this paper presents a comprehensive approach to tackle the challenges of data standardization and security in the IIoWT architecture.

Intelligent Grapevine Disease Detection Using IoT Sensor Network.

The Internet of Things (IoT) has gained significance in agriculture, using remote sensing and machine learning to help farmers make high-precision management decisions. This technology can be applied in viticulture, making it possible to monitor disease occurrence and prevent them automatically. The study aims to achieve an intelligent grapevine disease detection method, using an IoT sensor network that collects environmental and plant-related data. The focus of this study is the identification of the main parameters which provide early information regarding the grapevine's health. An overview of the sensor network, architecture, and components is provided in this paper. The IoT sensors system is deployed in the experimental plots located within the plantations of the Research Station for Viticulture and Enology (SDV) in Murfatlar, Romania. Classical methods for disease identification are applied in the field as well, in order to compare them with the sensor data, thus improving the algorithm for grapevine disease identification. The data from the sensors are analyzed using Machine Learning (ML) algorithms and correlated with the results obtained using classical methods in order to identify and predict grapevine diseases. The results of the disease occurrence are presented along with the corresponding environmental parameters. The error of the classification system, which uses a feedforward neural network, is 0.05. This study will be continued with the results obtained from the IoT sensors tested in vineyards located in other regions.

A robust algorithmic cum integrated approach of interval-valued fuzzy hypersoft set and OOPCS for real estate pursuit.

Due to the vast variety of aspects that must be made-many of which are in opposition to one another-choosing a home can be difficult for those without much experience. Individuals need to spend more time making decisions because they are difficult, which results in making poor choices. To overcome residence selection issues, a computational approach is necessary. Unaccustomed people can use decision support systems to help them make decisions of expert quality. The current article explains the empirical procedure in that field in order to construct decision-support system for selecting a residence. The main goal of this study is to build a weighted product mechanism-based decision-support system for residential preference. The said house short-listing estimation is based on several key requirements derived from the interaction between the researchers and experts. The results of the information processing show that the normalized product strategy can rank the available alternatives to help individuals choose the best option. The interval valued fuzzy hypersoft set (IVFHS-set) is a broader variant of the fuzzy soft set that resolves the constraints of the fuzzy soft set from the perspective of the utilization of the multi-argument approximation operator. This operator maps sub-parametric tuples into a power set of universe. It emphasizes the segmentation of every attribute into a disjoint attribute valued set. These characteristics make it a whole new mathematical tool for handling problems involving uncertainties. This makes the decision-making process more effective and efficient. Furthermore, the traditional TOPSIS technique as a multi-criteria decision-making strategy is discussed in a concise manner. A new decision-making strategy, "OOPCS" is constructed with modifications in TOPSIS for fuzzy hypersoft set in interval settings. The proposed strategy is applied to a real-world multi-criteria decision-making scenario for ranking the alternatives to check and demonstrate their efficiency and effectiveness.

The role of protein kinases in diabetic neuropathic pain: an update review.

Objectives: Diabetic neuropathic pain (DNP) is a debilitating symptom of diabetic neuropathy which seriously impairs patient's quality of life. Currently, there is no specific therapy for DNP except for duloxetine and gabapentin that show limited utility in alleviating DNP. The present review aims to discuss the central role of protein kinases in the pathogenesis of DNP and their therapeutic modulation. Methods: Scopus, PubMed, and Google scholar were searched up to January 2022 to find relevant studies with English language in which the roles of proteins kinases in DNP were examined. Results: DNP is associated with hyperactivity in pain sensory neurons and therapies aim to specifically suppress redundant discharges in these neurons without affecting the activity of other sensory and motor neurons. Transient receptor potential vanilloid 1 (TRPV1) and purinergic 2 × 7 receptors (P2 × 7R) are two receptor channels, highly expressed in pain sensory neurons and their blockade produces remarkable analgesic effects in DNP. The activities of receptor channels are mainly regulated by the protein kinases whose modulation provides remarkable analgesic effects in DNP models. Conclusion: Capsaicin, TRPV1 modulator, is the only agent successfully examined in clinical trials with promising effects in patients with DNP. Current data suggest that blocking calcium calmodulin dependent protein kinase II (CaMKII) is superior to other approaches, considering its pivotal role in regulating the pain neuron potentials. By this means, DNP alleviation is achievable without affecting the activity of other sensory or motor neurons.

DRLBTS: deep reinforcement learning-aware blockchain-based healthcare system.

Industrial Internet of Things (IIoT) is the new paradigm to perform different healthcare  applications with different services in daily life. Healthcare applications based on IIoT paradigm are widely used to track patients health status using remote healthcare technologies. Complex biomedical sensors exploit wireless technologies, and remote services in terms of industrial workflow applications to perform different healthcare tasks, such as like heartbeat, blood pressure and others. However, existing industrial healthcare technoloiges still has to deal with many problems, such as security, task scheduling, and the cost of processing tasks in IIoT based healthcare paradigms. This paper proposes a new solution to the above-mentioned issues and presents the deep reinforcement learning-aware blockchain-based task scheduling (DRLBTS) algorithm framework with different goals. DRLBTS provides security and makespan efficient scheduling for the healthcare applications. Then, it shares secure and valid data between connected network nodes after the initial assignment and data validation. Statistical results show that DRLBTS is adaptive and meets the security, privacy, and makespan requirements of healthcare applications in the distributed network.

Rise of Deep Learning Clinical Applications and Challenges in Omics Data: A Systematic Review.

This research aims to review and evaluate the most relevant scientific studies about deep learning (DL) models in the omics field. It also aims to realize the potential of DL techniques in omics data analysis fully by demonstrating this potential and identifying the key challenges that must be addressed. Numerous elements are essential for comprehending numerous studies by surveying the existing literature. For example, the clinical applications and datasets from the literature are essential elements. The published literature highlights the difficulties encountered by other researchers. In addition to looking for other studies, such as guidelines, comparative studies, and review papers, a systematic approach is used to search all relevant publications on omics and DL using different keyword variants. From 2018 to 2022, the search procedure was conducted on four Internet search engines: IEEE Xplore, Web of Science, ScienceDirect, and PubMed. These indexes were chosen because they offer enough coverage and linkages to numerous papers in the biological field. A total of 65 articles were added to the final list. The inclusion and exclusion criteria were specified. Of the 65 publications, 42 are clinical applications of DL in omics data. Furthermore, 16 out of 65 articles comprised the review publications based on single- and multi-omics data from the proposed taxonomy. Finally, only a small number of articles (7/65) were included in papers focusing on comparative analysis and guidelines. The use of DL in studying omics data presented several obstacles related to DL itself, preprocessing procedures, datasets, model validation, and testbed applications. Numerous relevant investigations were performed to address these issues. Unlike other review papers, our study distinctly reflects different observations on omics with DL model areas. We believe that the result of this study can be a useful guideline for practitioners who look for a comprehensive view of the role of DL in omics data analysis.

A hybrid cancer prediction based on multi-omics data and reinforcement learning state action reward state action (SARSA).

These days, the ratio of cancer diseases among patients has been growing day by day. Recently, many cancer cases have been reported in different clinical hospitals. Many machine learning algorithms have been suggested in the literature to predict cancer diseases with the same class types based on trained and test data. However, there are many research rooms available for further research. In this paper, the studies look into the different types of cancer by analyzing, classifying, and processing the multi-omics dataset in a fog cloud network. Based on SARSA on-policy and multi-omics workload learning, made possible by reinforcement learning, the study made new hybrid cancer detection schemes. It consists of different layers, such as clinical data collection via laboratories and tool processes (biopsy, colonoscopy, and mammography) at the distributed omics-based clinics in the network. The study considers the different cancer classes such as carcinomas, sarcomas, leukemias, and lymphomas with their types in work and processes them using the multi-omics distributed clinics in work. In order to solve the problem, the study presents omics cancer workload reinforcement learning state action reward state action "SARSA" (OCWLS) schemes, which are made up of an on-policy learning scheme on different parameters like states, actions, timestamps, reward, accuracy, and processing time constraints. The goal is to process multiple cancer classes and workload feature matching while reducing the time it takes to process in clinical hospitals that are spread out. Simulation results show that OCWLS is better than other machine learning methods regarding+ processing time, extracting features from multiple classes of cancer, and matching in the system.

A Framework for Susceptibility Analysis of Brain Tumours Based on Uncertain Analytical Cum Algorithmic Modeling.

Susceptibility analysis is an intelligent technique that not only assists decision makers in assessing the suspected severity of any sort of brain tumour in a patient but also helps them diagnose and cure these tumours. This technique has been proven more useful in those developing countries where the available health-based and funding-based resources are limited. By employing set-based operations of an arithmetical model, namely fuzzy parameterised complex intuitionistic fuzzy hypersoft set (FPCIFHSS), this study seeks to develop a robust multi-attribute decision support mechanism for appraising patients' susceptibility to brain tumours. The FPCIFHSS is regarded as more reliable and generalised for handling information-based uncertainties because its complex components and fuzzy parameterisation are designed to deal with the periodic nature of the data and dubious parameters (sub-parameters), respectively. In the proposed FPCIFHSS-susceptibility model, some suitable types of brain tumours are approximated with respect to the most relevant symptoms (parameters) based on the expert opinions of decision makers in terms of complex intuitionistic fuzzy numbers (CIFNs). After determining the fuzzy parameterised values of multi-argument-based tuples and converting the CIFNs into fuzzy values, the scores for such types of tumours are computed based on a core matrix which relates them with fuzzy parameterised multi-argument-based tuples. The sub-intervals within [0, 1] denote the susceptibility degrees of patients corresponding to these types of brain tumours. The susceptibility of patients is examined by observing the membership of score values in the sub-intervals.

Incorporating a Novel Dual Transfer Learning Approach for Medical Images.

Recently, transfer learning approaches appeared to reduce the need for many classified medical images. However, these approaches still contain some limitations due to the mismatch of the domain between the source domain and the target domain. Therefore, this study aims to propose a novel approach, called Dual Transfer Learning (DTL), based on the convergence of patterns between the source and target domains. The proposed approach is applied to four pre-trained models (VGG16, Xception, ResNet50, MobileNetV2) using two datasets: ISIC2020 skin cancer images and ICIAR2018 breast cancer images, by fine-tuning the last layers on a sufficient number of unclassified images of the same disease and on a small number of classified images of the target task, in addition to using data augmentation techniques to balance classes and to increase the number of samples. According to the obtained results, it has been experimentally proven that the proposed approach has improved the performance of all models, where without data augmentation, the performance of the VGG16 model, Xception model, ResNet50 model, and MobileNetV2 model are improved by 0.28%, 10.96%, 15.73%, and 10.4%, respectively, while, with data augmentation, the VGG16 model, Xception model, ResNet50 model, and MobileNetV2 model are improved by 19.66%, 34.76%, 31.76%, and 33.03%, respectively. The Xception model obtained the highest performance compared to the rest of the models when classifying skin cancer images in the ISIC2020 dataset, as it obtained 96.83%, 96.919%, 96.826%, 96.825%, 99.07%, and 94.58% for accuracy, precision, recall, F1-score, sensitivity, and specificity respectively. To classify the images of the ICIAR 2018 dataset for breast cancer, the Xception model obtained 99%, 99.003%, 98.995%, 99%, 98.55%, and 99.14% for accuracy, precision, recall, F1-score, sensitivity, and specificity, respectively. Through these results, the proposed approach improved the models' performance when fine-tuning was performed on unclassified images of the same disease.

COVID-CheXNet: hybrid deep learning framework for identifying COVID-19 virus in chest X-rays images.

The outbreaks of Coronavirus (COVID-19) epidemic have increased the pressure on healthcare and medical systems worldwide. The timely diagnosis of infected patients is a critical step to limit the spread of the COVID-19 epidemic. The chest radiography imaging has shown to be an effective screening technique in diagnosing the COVID-19 epidemic. To reduce the pressure on radiologists and control of the epidemic, fast and accurate a hybrid deep learning framework for diagnosing COVID-19 virus in chest X-ray images is developed and termed as the COVID-CheXNet system. First, the contrast of the X-ray image was enhanced and the noise level was reduced using the contrast-limited adaptive histogram equalization and Butterworth bandpass filter, respectively. This was followed by fusing the results obtained from two different pre-trained deep learning models based on the incorporation of a ResNet34 and high-resolution network model trained using a large-scale dataset. Herein, the parallel architecture was considered, which provides radiologists with a high degree of confidence to discriminate between the healthy and COVID-19 infected people. The proposed COVID-CheXNet system has managed to correctly and accurately diagnose the COVID-19 patients with a detection accuracy rate of 99.99%, sensitivity of 99.98%, specificity of 100%, precision of 100%, F1-score of 99.99%, MSE of 0.011%, and RMSE of 0.012% using the weighted sum rule at the score-level. The efficiency and usefulness of the proposed COVID-CheXNet system are established along with the possibility of using it in real clinical centers for fast diagnosis and treatment supplement, with less than 2 s per image to get the prediction result.

Federated-Learning Based Privacy Preservation and Fraud-Enabled Blockchain IoMT System for Healthcare.

These days, the usage of machine-learning-enabled dynamic Internet of Medical Things (IoMT) systems with multiple technologies for digital healthcare applications has been growing progressively in practice. Machine learning plays a vital role in the IoMT system to balance the load between delay and energy. However, the traditional learning models fraud on the data in the distributed IoMT system for healthcare applications are still a critical research problem in practice. The study devises a federated learning-based blockchain-enabled task scheduling (FL-BETS) framework with different dynamic heuristics. The study considers the different healthcare applications that have both hard constraint (e.g., deadline) and resource energy consumption (e.g., soft constraint) during execution on the distributed fog and cloud nodes. The goal of FL-BETS is to identify and ensure the privacy preservation and fraud of data at various levels, such as local fog nodes and remote clouds, with minimum energy consumption and delay, and to satisfy the deadlines of healthcare workloads. The study introduces the mathematical model. In the performance evaluation, FL-BETS outperforms all existing machine learning and blockchain mechanisms in fraud analysis, data validation, energy and delay constraints for healthcare applications.

Restricted Boltzmann Machine Assisted Secure Serverless Edge System for Internet of Medical Things.

The Internet of things (IoT) is a network of technologies that support a wide variety of healthcare workflow applications to facilitate users' obtaining real-time healthcare services. Many patients and doctors' hospitals use different healthcare services to monitor their healthcare and save their records on the servers. Healthcare sensors are widely linked to the outside world for different disease classifications and questions. These applications are extraordinarily dynamic and use mobile devices to roam several locales. However, healthcare apps confront two significant challenges: data privacy and the cost of application execution services. This work presents the mobility-aware security dynamic service composition (MSDSC) algorithmic framework for workflow healthcare based on serverless, serverless, and restricted Boltzmann machine mechanisms. The study suggests the stochastic deep neural network trains probabilistic models at each phase of the process, including service composition, task sequencing, security, and scheduling. The experimental setup and findings revealed that the developed system-based methods outperform traditional methods by 25% in terms of safety and 35% in application cost.

Event-Specific Transmission Forecasting of SARS-CoV-2 in a Mixed-Mode Ventilated Office Room Using an ANN.

The emerging novel variants and re-merging old variants of SARS-CoV-2 make it critical to study the transmission probability in mixed-mode ventilated office environments. Artificial neural network (ANN) and curve fitting (CF) models were created to forecast the R-Event. The R-Event is defined as the anticipated number of new infections that develop in particular events occurring over the course of time in any defined space. In the spring and summer of 2022, real-time data for an office environment were collected in India in a mixed-mode ventilated office space in a composite climate. The performances of the proposed CF and ANN models were compared with respect to traditional statistical indicators, such as the correlation coefficient, RMSE, MAE, MAPE, NS index, and a20-index, in order to determine the merit of the two approaches. Thirteen input features, namely the indoor temperature (TIn), indoor relative humidity (RHIn), area of opening (AO), number of occupants (O), area per person (AP), volume per person (VP), CO2 concentration (CO2), air quality index (AQI), outer wind speed (WS), outdoor temperature (TOut), outdoor humidity (RHOut), fan air speed (FS), and air conditioning (AC), were selected to forecast the R-Event as the target. The main objective was to determine the relationship between the CO2 level and R-Event, ultimately producing a model for forecasting infections in office building environments. The correlation coefficients for the CF and ANN models in this case study were 0.7439 and 0.9999, respectively. This demonstrates that the ANN model is more accurate in R-Event prediction than the curve fitting model. The results show that the proposed ANN model is reliable and significantly accurate in forecasting the R-Event values for mixed-mode ventilated offices.

A Robust Framework for Data Generative and Heart Disease Prediction Based on Efficient Deep Learning Models.

Biomarkers including fasting blood sugar, heart rate, electrocardiogram (ECG), blood pressure, etc. are essential in the heart disease (HD) diagnosing. Using wearable sensors, these measures are collected and applied as inputs to a deep learning (DL) model for HD diagnosis. However, it is observed that model accuracy weakens when the data gathered are scarce or imbalanced. Therefore, this work proposes two DL-based frameworks, GAN-1D-CNN, and GAN-Bi-LSTM. These frameworks contain: (1) a generative adversarial network (GAN) and (2) a one-dimensional convolutional neural network (1D-CNN) or bi-directional long short-term memory (Bi-LSTM). The GAN model is utilized to augment the small and imbalanced dataset, which is the Cleveland dataset. The 1D-CNN and Bi-LSTM models are then trained using the enlarged dataset to diagnose HD. Unlike previous works, the proposed frameworks increase the dataset first to avoid the prediction bias caused by the limited data. The GAN-1D-CNN achieved 99.1% accuracy, specificity, sensitivity, F1-score, and 100% area under the curve (AUC). Similarly, the GAN-Bi-LSTM obtained 99.3% accuracy, 99.2% specificity, 99.3% sensitivity, 99.2% F1-score, and 100% AUC. Furthermore, time complexity of proposed frameworks is investigated with and without principal component analysis (PCA). The PCA method reduced prediction times for 61 samples using GAN-1D-CNN and GAN-Bi-LSTM to 68.8 and 74.8 ms, respectively. These results show that it is reliable to use our frameworks for augmenting limited data and predicting heart disease.