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J Obstet Gynaecol Res ; 24(1): 21-5, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9564101

ABSTRACT

OBJECTIVE: To evaluate the ability of leukocyte esterase dipstick test (LET) performed in cervical mucus to predict direct immunofluorescent (DIF)-verified Chlamydia trachomatis (Ct) cervical infection. METHOD: Eighty women with inflammatory cervico-vaginal smear were submitted to both an endocervical smear, to verify Ct cervicitis by DIF technique; and a cervical mucus sample to perform LET. Results of LET and DIF were matched. RESULTS: Among 30 Chlamydial positive subjects, cervical mucus esterase test was positive in 28 (93.3%); while among 50 Chlamydial negative controls, esterase test was negative in 43 subject (86%). The sensitivity, specificity, positive and negative predictive values for LET were 93.3%, 86%, 80% and 95% respectively. CONCLUSION: Cervical mucus LET is a simple, cost effective screening test, with promising accuracy, for Ct cervical infection among women with inflammatory cervico-vaginal smears.


Subject(s)
Carboxylic Ester Hydrolases/analysis , Cervix Mucus/enzymology , Chlamydia Infections/diagnosis , Chlamydia trachomatis , Mass Screening/methods , Uterine Cervicitis/diagnosis , Biomarkers/analysis , Chlamydia Infections/enzymology , Chlamydia Infections/pathology , Cohort Studies , Female , Fluorescent Antibody Technique, Direct , Humans , Pilot Projects , Predictive Value of Tests , Uterine Cervicitis/enzymology , Uterine Cervicitis/pathology , Vaginal Smears
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