ABSTRACT
The Breast Cancer Revealed initiative was designed and conducted to know the status of breast cancer at each point of breast cancer care, through i) prevention, ii) detection, iii) diagnosis, iv) treatment, and iv) the capacity of our health systems. The expert panel from 11 Latin American countries identified several strategies and proposed high impact priorities, including implementation of prevention policies, improve primary healthcare capacity for breast cancer screening, have adequate infrastructure to make effective and timely diagnoses, have a multidisciplinary team in the treatment process, access to a variety of treatments for all types of patients, have a coordinated and articulated system from primary care to specialized hospital. In a region with limited resources, prioritization in high-impact strategies for breast cancer control could lead to improved clinical outcomes and quality of life for our patients.
Subject(s)
Breast Neoplasms , Humans , Female , Breast Neoplasms/diagnosis , Breast Neoplasms/epidemiology , Breast Neoplasms/therapy , Latin America/epidemiology , Quality of Life , Delivery of Health Care , Early Detection of CancerABSTRACT
Metastasis to the breast from extramammary tumors are uncommon and metastatic colon carcinoma (MCC) to the breast is extremely rare. A case history is presented of a 42 year-old woman with a finding of a breast lump. One year before,she had undergone an anterior colon resection for a rectal carcinoma. Mammographic examination revealed a high density, well demarcated, 3 cm lesion located in the upper outer quadrant of left breast, along with smaller multiple bilateral nodules. Following breast biopsy, the final diagnosis of MCC was based on the absence of any precursor lesion within the breast (no surrounding ductal carcinoma in situ) and of the expression of cytokeratin 20 and ß-catenin on immunohistochemistry.The treatment strategy for metastatic breast disease is based on a proper assessment of such cases by surgeons,radiologists and pathologists.
Subject(s)
Adenocarcinoma/secondary , Breast Neoplasms/secondary , Colonic Neoplasms/pathology , Adult , Female , HumansABSTRACT
A 35-year-old woman presented with abdominal pain and weight loss. Pelvic computed tomography showed a 15 cm mass in the left ovary. Grossly, the removed ovary was completely replaced by a solid tumor mass. On histological analysis (100 sections), the lesion showed the typical morphological features of dysgerminoma (20%) admixed with a major (80%) fibrosarcoma component. Tumors did not have well-demarcated boundaries with a close intermingling of both cell types. Despite surgery and combination chemotherapy, the disease progressed rapidly and the patient died of disease 18 months after diagnosis. Review of the literature showed that soft tissue sarcomas of several types may occasionally be associated with gonadal and extragonadal mixed germ-cell tumors or with spermatocytic seminoma of the testis. However, no previously published report of an ovarian fibrosarcoma associated with a pure dysgerminoma was found in the literature.
