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1.
Gut Liver ; 8(2): 224-7, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24672666

ABSTRACT

Eosinophilic gastroenteritis (EGE) is a rare disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, especially the stomach and duodenum. EGE has vague, nonspecific symptoms, including nausea, vomiting, abdominal pain, diarrhea, weight loss, ascites, and malabsorption. Here, we report a patient with EGE presenting with concurrent acute pancreatitis and ascites. A 68-year-old woman was admitted with abdominal pain, nausea, vomiting, and watery diarrhea. Laboratory findings revealed elevated serum titers of amylase, lipase, and peripheral blood eosinophil count. An abdominopelvic computed tomography scan showed a normal pancreas, moderate amount of ascites, and duodenal thickening. A esophagogastroduodenoscopy showed patchy erythematous mucosal lesions in the 2nd portion of the duodenum. Biopsies from the duodenum indicated eosinophilic infiltration in the lamina propria. The patient was successfully treated with prednisolone and montelukast. Despite its unusual occurrence, EGE may be considered in the differential diagnosis of unexplained acute pancreatitis, especially in a patient with duodenal edema on imaging or peripheral eosinophilia.


Subject(s)
Ascites/etiology , Enteritis/complications , Eosinophilia/complications , Gastritis/complications , Pancreatitis/etiology , Acute Disease , Aged , Female , Humans , Tomography, X-Ray Computed
2.
Clin Mol Hepatol ; 19(3): 305-8, 2013 Sep.
Article in English | MEDLINE | ID: mdl-24133669

ABSTRACT

Autoimmune hepatitis (AIH) has been reported in association with Sjögren's syndrome (SS). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and SS in a 53-year-old woman after the consumption of herbal medicines is described. After admission, the patient complained of dryness in her mouth, and she was subsequently diagnosed with SS, which had not been detected previously. The patient's bilirubin and aminotransferase levels initially decreased following conservative management; however, they later began to progressively increase. A diagnosis of AIH was made based on the scoring system proposed by the International Autoimmune Hepatitis Group. The patient was administered a combination of prednisolone and azathioprine, and the results of follow-up liver-function tests were found to be within the normal range. This is an unusual case of AIH and SS triggered simultaneously by the administration of herbal medicines.


Subject(s)
Hepatitis, Autoimmune/diagnosis , Herbal Medicine , Sjogren's Syndrome/diagnosis , Alanine Transaminase/blood , Aspartate Aminotransferases/blood , Azathioprine/therapeutic use , Bilirubin/blood , Female , Hepatitis, Autoimmune/complications , Hepatitis, Autoimmune/drug therapy , Humans , Liver/pathology , Liver Function Tests , Middle Aged , Prednisolone/therapeutic use , Sjogren's Syndrome/complications , Sjogren's Syndrome/drug therapy
3.
Chonnam Med J ; 49(1): 50-3, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23678479

ABSTRACT

In contrast to widely recognized venous thrombotic complications, peripheral arterial thrombosis as a complication of nephrotic syndrome, especially without preceding iatrogenic venous puncture, corticosteroid treatment, or coagulation factor abnormalities, has rarely been reported in adult female patients. We report the case of a 39-year-old woman who presented with pain in the right lower leg accompanied by minimal change nephrotic syndrome. Lower-extremity angiography showed total occlusion of the right superficial femoral artery. Thrombectomy was performed with a balloon catheter, and the thrombi were successfully aspirated. Our experience indicates that even if few traditional risk factors for atherosclerosis are identified, a high index of suspicion and aggressive treatment of arterial thrombosis in adult nephrotic syndrome are crucial to minimize serious ischemic injuries.

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