ABSTRACT
BACKGROUND: Schwannoma is generally a benign tumour developing from Schwann cells. AIM: To study epidemiological, clinical and pathological features of scwannoma. METHODS: Retrospective study about 26 cases of cutaneous schwannoma collected in our department over 24 years. RESULTS: Our patients were 12 females and 14 males. Mean age was 30 years. Clinically, schwannoma was a subcutaneous tumour which was painful in 11 cases. Individual tumours were located on the limbs (10 cases), on the head (9 cases) and the trunk (5 cases). Multiple tumours were seen in two patients. Histopathological examination confirmed the diagnosis of schwannoma in all cases. Treatment was complete surgical excision in all cases. CONCLUSION: Cutaneous location of schwannoma is not rare. Usually, and contrarily to our series, there is no sex predominance. Clinically, schwannoma is located on the limbs and head. The diagnosis is confirmed by histopathological examination. Malignant epitheloid schwannoma diagnosed in one of our patients is a rare tumour. Schwannomas usually grow slowly and are poorly invasive. Malignant degeneration is exceptional. Treatment is complete surgical excision.
Subject(s)
Neurilemmoma/epidemiology , Skin Neoplasms/epidemiology , Adolescent , Adult , Aged , Child , Cohort Studies , Disease Progression , Female , Humans , Male , Middle Aged , Neurilemmoma/diagnosis , Neurilemmoma/pathology , Neurilemmoma/surgery , Recurrence , Retrospective Studies , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , Skin Neoplasms/surgery , Young AdultABSTRACT
Pemphigoid gestationis is an acute autoimmune subepidermal bullous dermatosis which occurs during pregnancy and post partum. It is a rare disease which incidence vary from 1/1700 to 1/60000 pregnancy. It occurs in young woman aged between 20 to 40 years. The authors try throughout a retrospective study of 30 cases of pemphigoid gestationis to drave the epidemiological and clinical profile and the immunopathological characteristics of this affection.
Subject(s)
Pemphigoid Gestationis/epidemiology , Adult , Age Factors , Anti-Inflammatory Agents/therapeutic use , Autoimmune Diseases/epidemiology , Biopsy , Diagnosis, Differential , Female , Fluorescent Antibody Technique, Direct , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Middle Aged , Parity , Prednisone/therapeutic use , Pregnancy , Pregnancy Outcome , Pregnancy Trimesters , Puerperal Disorders/epidemiology , Retrospective Studies , Tunisia/epidemiologyABSTRACT
Erosive oral lichen planus (EOLP) is uncommon. We present nine cases of EOLP in patients aged from 39 to 77 years. The aim of our retrospective study was to determine the clinical particularities and the treatment difficulties of this disease.
