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[Malignant thyroid neoplasms in the territories of the Russian Federation exposed as a consequence of the accident at the Chernobyl Atomic Electric Power Station]. / Zlokachestvennye novoobrazovaniia shchitovidnoi zhelezy na territoriiakh Rossiiskoi Federatsii, postradavshikh vsledstvie avarii na Chernobyl'skoi AES.

Remennik, L V; Starinskii, V V; Chissov, V I; Mokina, V D; Shchepliagina, L A; Petrova, G V; Rubtsova, M M; Kharchenko, N V; Gretsova, V I.

Vopr Onkol ; 41(2): 29-34, 1995.

Article in Russian | MEDLINE | ID: mdl-7483426

Subject(s)

Neoplasms, Radiation-Induced/epidemiology , Power Plants , Radioactive Hazard Release , Thyroid Neoplasms/epidemiology , Adolescent , Adult , Age Distribution , Aged , Child , Child, Preschool , Female , Humans , Incidence , Infant , Infant, Newborn , Male , Middle Aged , Neoplasms, Radiation-Induced/etiology , Russia/epidemiology , Sex Distribution , Thyroid Neoplasms/etiology , Ukraine

[The initial experience of assessing scientific research work in the Expert Council on Malignant Neoplasms]. / Pervyi opyt otsenki NIR v ékspertnom sovete po zlokachestvennym novoobrazovaniiam.

Proshchenko, B G; Vernikova, A A; Gorbunova, I A; Mokina, V D.

Vopr Onkol ; 36(6): 661-6, 1990.

Article in Russian | MEDLINE | ID: mdl-2378084

Subject(s)

Academies and Institutes/organization & administration , Medical Oncology , Animals , Health Priorities , Health Services Research , Humans , Program Evaluation , USSR

[Planning of research studies in the field of oncology]. / O planirovanii nauchnykh issledovanii v oblasti onkologii.

Proshchenko, V G; Vernikova, A A; Mokina, V D.

Vopr Onkol ; 34(2): 151-6, 1988.

Article in Russian | MEDLINE | ID: mdl-3348004

Subject(s)

Medical Oncology , Research , Humans , USSR

[Use of biochemical criteria in the prognosis of the efficacy of chemotherapy in tumors]. / Ispol'zovanie biokhimicheskikh kriteriev dlia prognozirovaniia éffektivnosti khimioterapii opukholei.

Gerasimova, G K; Matveev, L V; Mokina, V D.

Vestn Akad Med Nauk SSSR ; (12): 15-9, 1981.

Article in Russian | MEDLINE | ID: mdl-7331487

Subject(s)

Antimetabolites, Antineoplastic/therapeutic use , Neoplasms, Experimental/metabolism , Neoplasms/drug therapy , Animals , DNA, Neoplasm/metabolism , Humans , Neoplasms, Experimental/drug therapy , RNA, Neoplasm/metabolism

[Comparison of free ribonucleotide pool in the spleens of C57BL and DBA/2 mice and in leukemia cells sensitive and resistant to 5-fluorouracil]. / Sravnenie fonda svobodnykh ribonukleotidov v selezenke myshei C57BL i DBA/2 i v kletkakh leikozov, chuvstvitel'nykh i ustoichivykh k 5-ftoruratsilu.

Gerasimova, G K; Mokina, V D; Sidorova, T A.

Biokhimiia ; 43(1): 163-9, 1978 Jan.

Article in Russian | MEDLINE | ID: mdl-623843

ABSTRACT

The amount of free purine and pyrimidine ribonucleotides in the spleens of mice (C57Bl and DBA/2) and in lympholeukemia cells (La and L1210), sensitive and with induced resistance to 5-fluorouracil, was determined by chromatography on a column with DEAE-cellulose. It was found that the cytidine ribonucleotide pool in the spleens of DBA/2 mice is 2 times lower as compared to C57Bl mice. The lympholeukemia cells (La and L1210) isolated from the animals also differed in their uridine nucleotide pools. The development of leukemia was accompanied by a decrease in ATP and GTP. No significant changes in the total amount of pyrimidine nucleotides under developing resistance to 5-fluororuacil were observed.

Subject(s)

Fluorouracil/pharmacology , Leukemia L1210/metabolism , Leukemia, Experimental/metabolism , Ribonucleotides/metabolism , Spleen/metabolism , Animals , Mice , Mice, Inbred C57BL , Mice, Inbred DBA , Purine Nucleotides/metabolism , Pyrimidine Nucleotides/metabolism

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