1.
Res Vet Sci
; 93(2): 1036-8, 2012 Oct.
Article
in English
| MEDLINE
| ID: mdl-22100245
ABSTRACT
There is growing interest in utilizing replicating oncolytic viruses as cancer therapeutics agents. The effectiveness of myxoma virus-induced oncolysis was evaluated in two feline cancer cell cultures. Although myxoma virus is a rabbit-specific pathogen, protein expression driven by myxoma virus and production of infectious viral particles were detected. Cell death occurred in primary feline cancer cells within 48 h of inoculation with myxoma virus. Future studies to determine if other feline neoplasms are susceptible to myxoma virus infection are warranted.
Subject(s)
Apoptosis/physiology , Carcinoma/virology , Myxoma virus/physiology , Animals , Cat Diseases , Cats , Cell Culture Techniques , Female , Mammary Neoplasms, Animal
2.
Med Clin (Barc)
; 86(17): 709-11, 1986 May 03.
Article
in Spanish
| MEDLINE
| ID: mdl-3736160