Effects of CYP3A5 Genotype on Tacrolimus Pharmacokinetics and Graft-versus-Host Disease Incidence in Allogeneic Hematopoietic Stem Cell Transplantation.

Tacrolimus (Tac) is pivotal in preventing acute graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (alloHSCT). It has been reported that genetic factors, including CYP3A5*3 and CYP3A4*22 polymorphisms, have an impact on Tac metabolism, dose requirement, and response to Tac. There is limited information regarding this topic in alloHSCT. The CYP3A5 genotype and a low Tac trough concentration/dose ratio (Tac C0/D ratio) can be used to identify fast metabolizers and predict the required Tac dose to achieve target concentrations earlier. We examined 62 Caucasian alloHSCT recipients with a fast metabolizer phenotype (C0/dose ratio ≤ 1.5 ng/mL/mg), assessing CYP3A5 genotypes and acute GVHD incidence. Forty-nine patients (79%) were poor metabolizers (2 copies of the variant *3 allele) and 13 (21%) were CYP3A5 expressers (CYP3A5*1/*1 or CYP3A5*1/*3 genotypes). CYP3A5 expressers had lower C0 at 48 h (3.7 vs. 6.2 ng/mL, p = 0.03) and at 7 days (8.6 vs. 11.4 ng/mL, p = 0.04) after Tac initiation, tended to take longer to reach Tac therapeutic range (11.8 vs. 8.9 days, p = 0.16), and had higher incidence of both global (92.3% vs. 38.8%, p < 0.001) and grade II-IV acute GVHD (61.5% vs. 24.5%, p = 0.008). These results support the adoption of preemptive pharmacogenetic testing to better predict individual Tac initial dose, helping to achieve the therapeutic range and reducing the risk of acute GVHD earlier.

Intervención fisioterapéutica en fibromialgia / Physiotherapeutic intervention in fibromyalgia

Introducción: La fibromialgia afecta el movimiento corporal. Provoca dolor en puntos claves, causa molestias musculoesqueléticas y limita la actividad de las personas. Se ha descrito que la fisioterapia mejora de calidad de vida de estos pacientes. Objetivo: Identificar los test de evaluación y los procesos de intervención fisioterapéutica utilizados en la fibromialgia. Métodos: Se realizó una revisión de literatura en PubMed, ScientsDirect, SciELO y LILLACS, con la terminología MeSH y DeCS, entre 2017 y 2022. Resultados: La escala visual análoga y la algometría por presión son los test utilizados para el dolor. La hidroterapia, el cupping, la punción seca, el masaje sueco, los ejercicios respiratorios y los aeróbicos resultan los métodos de intervención con más uso. Conclusiones: Los procesos de intervención se deben plantear según las evaluaciones del dolor y la funcionalidad en la persona. El tratamiento fisioterapéutico de la fibromialgia debe tener un componente de ejercicio físico aérobico y fuerza para disminuir la fatiga; devolverle al músculo su funcionalidad y aumentar la capacidad aeróbica(AU)

Introduction: Fibromyalgia affects body movement. It causes pain in key points, it causes musculoskeletal discomfort and it limits the persons's activity. It has been described that physiotherapy improves the quality of life of these patients. Objective: To identify the evaluation tests and physiotherapy intervention processes used in fibromyalgia. Methods: A literature review was carried out in PubMed, ScientsDirect, Scielo and LILLACS, with the terminology MeSH and DeCS, from 2017 to 2022. Results: The visual analogue scale and pressure algometry are the tests used for pain. Hydrotherapy, cupping, dry needling, Swedish massage, breathing exercises and aerobics are the most commonly used intervention methods. Conclusions: Intervention processes should be planned according to the evaluations of pain and functionality in the person. The physiotherapy treatment of fibromyalgia must have a component of aerobic physical exercise and strength to reduce fatigue, to return the muscle to its functionality and increase aerobic capacity(AU)

Una herramienta de intervención eficaz en el adulto mayor institucionalizado

Introducción: El proceso de envejecimiento afecta el equilibrio y la movilidad de los adultos mayores institucionalizados, los cuales pueden adquirir independencia funcional gracias al ejercicio. Objetivo: Determinar el efecto de un programa de ejercicios anticaídas y desempeño físico funcional de los adultos mayores institucionalizados. Métodos: Se realizó un estudio de casos múltiples, de tipo preexperimental, prospectivo y longitudinal; además, un muestreo no probabilístico de 12 adultos mayores institucionalizados con registro de caídas durante 2015. La medición de equilibrio y desempeño físico se hizo antes y después de la aplicación del programa de ejercicios. Los datos se analizaron con el programa SPSS 22.0 y la prueba Shapiro-Wilk determinó la normalidad de las variables. Los test T de student y Wilcoxon verificaron el nivel de significancia y estadístico. D de Cohen midió la magnitud del efecto sobre la aplicación clínica. Para las características sociodemográficas y clínicas se utilizó un análisis bivariado exploratorio; y los análisis multivariados emplearon ANOVA y estadístico ETA 2. Resultados: Se determinaron cambios estadísticamente significativos en equilibrio y frecuencia de caídas con p = 0,05 y 0,008; y magnitudes del efecto grande d = 2,150 y d = 1,16, respectivamente. Las características sociodemográficas y clínicas no intervinieron en el efecto del programa sobre el equilibrio y el desempeño físico funcional. Conclusiones: La aplicación del programa anticaídas mejoró el equilibrio y disminuyó las caídas en adultos mayores institucionalizados.

Introduction: The aging process affects the balance and mobility of older adults living in an institution, who can acquire functional independence thanks to exercise. Objective: To determine the effect of a program of anti-fall exercises and functional physical performance of older adults living in an institution. Methods: A multi-case, pre-experimental, prospective and longitudinal study was carried out in a non-probabilistic sampling of 12 older adults living in an institution with a record of falls during 2015. Balance and physical performance were measured before and after the use of this program of exercises. The data was analyzed with SPSS 22.0 program and Shapiro-Wilk test determined the normality of the variables. Student's and Wilcoxon's T tests verified the level of significance and statistics. Cohen's D measured the magnitude of the effect on clinical application. For sociodemographic and clinical characteristics, an exploratory bivariate analysis was used, and the multivariate analyzes used ANOVA and ETA 2 statistic. Results: Statistically significant changes in balance and frequency of falls were determined with p = 0.05 and 0.008; and large effect sizes d = 2.150 and d = 1.16, respectively. Sociodemographic and clinical characteristics did not intervene in the effect of the program on balance and functional physical performance. Conclusions: The use of the anti-fall program improved balance and decreased falls in older adults living in an institution.

Uso de psicofármacos en personas con discapacidad intelectual en Extremadura, España / Use of Psychotropic Drugs in People with Intellectual Disability in Extremadura, Spain

Resumen El uso de psicofármacos es frecuente en adultos con discapacidad intelectual, a menudo por conductas desafiantes en ausencia de diagnóstico de trastorno mental. Investigaciones previas cuestionan la eficacia de estos tratamientos a falta de una enfermedad psiquiátrica, y destacan sus efectos secundarios. El objetivo de esta investigación es analizar el uso de psicofármacos en función del diagnóstico de enfermedad mental y conducta desafiante, así como la distribución de la población según el uso de psicofármacos en 569 adultos con discapacidad intelectual que presentan enfermedad mental o conductas desafiantes. Los datos acerca de la elevada prescripción de psicofármacos y, especialmente, de antipsicóticos alertan sobre la necesidad de una profunda revisión de la práctica clínica que permita reducir el uso de esta medicación en el tratamiento de la conducta y los trastornos mentales en esta población, para garantizar una atención de calidad y el respeto de los derechos de estas personas.

Abstract The use of psychotropic drugs in adults with an intellectual disability is frequent, often for defiant conduct due to the lack of a diagnosis of a mental disorder. Previous research has questioned the efficacy of such treatments in the absence of a psychiatric illness, and the stress has been on the side effects. The objective of this research is to analyze the use of psychotropic drugs based on the diagnosis of mental illness and behavioral disorders, as well as the distribution of the sample according to the use of psychotropic drugs in 569 adults with an intellectual disability who also suffer a mental illness and/or defiant conduct. Our data about the high prescription of psychotropic drugs and especially antipsychotics, warns of the need for a profound review of the clinical practice that would allow a reduction in the use of psychotropic drugs in the treatment of mental disorders and behaviour in the said collective, so as to guarantee quality mental health care for these persons and respect for their rights.

A systematic review of EEG neurofeedback in fibromyalgia to treat psychological variables, chronic pain and general health.

This paper is the first up-to-date review of the various EEG-neurofeedback treatments for fibromyalgia patients and their psychological, physiological and general health consequences. Searches were made of the PubMed, PsycNet, Google Scholar and Scopus databases according to PRISMA guidelines for empirical peer-reviewed articles on EEG-neurofeedback treatment of fibromyalgia, yielding a final selection of 17 studies that met the inclusion criteria: (1) published articles and doctoral theses; (2) conducted between 2000 and 2022; (3) reporting empirical and quantitative data. These articles show that there is a wide range of protocols with different designs and procedures to treat fibromyalgia using EEG-neurofeedback techniques. The main symptoms that showed improvement were anxiety, depression, pain, general health and symptom severity, whilst the most commonly used method was traditional EEG neurofeedback based on a sensorimotor rhythm protocol. It may be concluded from the review that the lack of consistency and uniqueness of the protocols makes it very difficult to generalise results, despite the individual improvements identified. This review provides instructions and information that could guide future research and clinical practise, with the data extracted helping to gain a deeper understanding of the state of the art and the needs of the technique for this population group.

Psicopatía subclínica y estilos de relación de pareja / Subclinical psychopathy and relationship styles

Diferentes estudios ponen de manifiesto la relación entre psicopatía subclínica y las estrategias de distanciamiento y evitación que impiden la formación de vínculos emocionales estables y duraderos en la pareja. El estudio analiza la psicopatía subclínica y el estilo de relación/tipo de amor en una muestra de 1289 universitarios, para determinar su frecuencia, así como la relación entre la psicopatía y el estilo de relación del alumnado universitario. Se utilizó el “Cuestionario de psicopatía integrada/subclínica” (CUPIS) y la “Escala triangular del amor” (TLS). Se encontró que un importante porcentaje de universitarios presentan rasgos que caracterizan a la psicopatía subclínica. Además, a mayor puntuación en psicopatía menor es la intimidad, la pasión y el compromiso en la relación de pareja del alumnado universitario. Asimismo, constatamos que la psicopatía subclínica predice en mayor medida la falta de intimidad y compromiso en las relaciones íntimas. En conclusión, destacamos que en psicopatía subclínica se presentan bajos patrones de intimidad y compromiso en las relaciones, por lo que es probable que estas no sean estables en el tiempo. (AU)

Different studies show the relationship between subclinical psychopathy and the strategies of distancing and avoidance that prevent the formation of stable and lasting emotional bonds in the couple. The study analyses subclinical psychopathy and the relationship style/love type in a sample of 1289 university students to determine its frequency, as well as the relationship between psychopathy and the relationship style/love type. The Integrated/Subclinical Psychopathy Questionnaire (CUPIS) and the Triangle of Love Scale (TLS) were used. It was found that a significant percentage of these students present features that characterise subclinical psychopathy. In addition, it was found that the higher the score in psychopathy, the lower the intimacy, passion and commitment in their relationships. Furthermore, subclinical psychopathy was found to be a greater predictor of a lack of intimacy and commitment in intimate relationships between couples. In conclusion, we highlight that, in subclinical psychopathy, there are low patterns of intimacy and commitment in relationships; so these are unlikely to remain stable over time. (AU)

Past and future episodic detail retrieval is reduced among clinically normal older adults at higher genetic risk for late-onset Alzheimer's disease.

OBJECTIVE: Remembering and imagining personal events that are rich in episodic (i.e., event-specific) detail is compromised in older adults who have mild cognitive impairment, a known risk factor for Alzheimer's disease dementia. Less clear is whether lower episodic detail generation is associated with higher risk for Alzheimer's disease dementia before mild clinical decline is detectable. METHOD: We compared past and future autobiographical thinking in clinically normal older adult carriers of the Alzheimer's disease-associated apolipoprotein E e4 allele (APOE4; n = 39) to demographically and neuropsychologically similar non-APOE4 carriers (n = 43). RESULTS: APOE4 carriers showed a significant reduction for episodic details when remembering past events (d = .47) and imagining future events (d = .46), but not for nonepisodic details. CONCLUSIONS: These findings suggest that APOE4 is associated with a selective reduction of episodic detail during past and future autobiographical thinking among clinically normal older adults. Reduced episodic detail generation, therefore, may be an early cognitive associate of higher risk for Alzheimer's disease dementia. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Well-Being at Work: Burnout and Engagement Profiles of University Workers.

The main objective of this study is to analyze well-being at work, considering burnout and engagement distributed in profiles, and to observe how they relate to well-being outside work. The data came from a representative sample of workers (n = 565) at the University of Extremadura (Spain), both teaching and research academic staff (TRAS) and service and administrative staff (SAS). We performed the data analysis by using latent profile analysis, and the results show evidence that workers from both groups were distributed across four profiles. As expected, we verified that workers in the profile with high burnout and low engagement had lower well-being outside work than workers in the profile with high engagement and low burnout. We also observed that engagement mitigated the negative effects of burnout on workers in profiles with moderate levels of burnout, who showed better well-being outside work when they had higher engagement. These differences are discussed, and their practical implications and suggestions for future research are provided.

Moral Disengagement Mechanisms and Personality Dimensions Implicit to Homophobia.

Recent advances in sexual equality and diversity have not been able to mitigate the serious problem of discrimination suffered by sexual minorities. The most serious cases involve violence and physical or psychological aggression towards sexual orientations that differ from the heterosexual norm. This research analyses the dimensions of the personality and the moral disengagement mechanisms related to homophobia and the predictive value they have for hostile attitudes towards sexual diversity. The sample was made up of 849 university students between 18 and 24 years of age. The instruments used were the Modern Homophobia Scale (MHS), the Mechanisms of Moral Disengagement Scale (MMDS), and the reduced version of the Neo Personality Inventory-Reduced Version (NEO-FFI). The results show the involvement of moral disengagement in homophobia. It highlights evidence of subtle intimidatory behaviour patterns of rejection towards homosexuality. Furthermore, the low levels in the dimensions of a friendly personality and openness to experiences can be seen to predict homophobic behaviour. Thus, young people fall back on diverse mechanisms of moral disengagement to justify harmful attitudes towards the LGTBI collective. The results of the research are particularly relevant and useful for setting up programmes aimed at preventing and mitigating this serious problem of sexual discrimination.

Psychological Tasks Used in Neuroimaging with Male Perpetrators of Intimate Partner Violence against Women: A Systematic Review.

This bibliographic review analyses the utility for psychologists of using neuroimaging tests and psychological or neuropsychological tests at the same time for studying the functioning of the brain in male abusers condemned for intimate partner violence against women (IPVAW). So as to be able to find an answer, we reviewed the available studies that investigated the structure or functioning of the brain. The results of these reviewed works of research show the benefits of using neuroimaging applied to male abusers, together with the use, either simultaneously or not, of other types of psychological, neuropsychological, or observational tests to complement and/or amplify the results of the neuroimaging techniques, as this can help us to advance in the knowledge of neuroscience as concerns the mind of the male abuser.

Profile of Subclinical Psychopathy in Spanish University Students.

Psychopaths are portrayed as deceitful, manipulative, domineering and narcissistic; the result of an irregular and irresponsible interpersonal style that harms both the psychopath him/herself and others. Furthermore, psychopathy is frequently associated with both violent and antisocial conduct. However, subclinical psychopaths are known for manifesting this type of profile without committing crimes. The objective of this study is to examine the differences that exist in subclinical psychopathy concerning gender, the number of intimate relationships and the age of the university student. The number of university students participating was 1289. They were given the Integrated/Subclinical Psychopathy Questionnaire (CUPIS). The results show that, in subclinical psychopathy, men present higher scores than women and younger persons have higher scores than older persons. In addition, the scores in psychopathy are higher for students who have had a larger number of intimate relationships. The contributions of this study allow us to determine the profile associated with subclinical psychopathy.

Youth Serial Killers: Psychological and Criminological Profiles.

Serial murder is a specific type of violent crime that falls into the crime category of multicide. According to the nomenclature of the Federal Bureau of Investigation's Violent Crime Classification Manual and Academic Researchers for the Classification of Violent Crimes, most serial killers are adults. However, serial murder is also committed by young people, although to a lesser extent. Young serial killers are a topic of relevance in areas such as psychology, criminology, and the justice system. Given that the study of the variables that could be the basis of such multicide criminality is not conclusive, the need for further research is evident. The homicides perpetrated by children and young people point to a social panorama that is alarming due to their young age. This issue is prevalent enough to conduct a review. The performed review concludes the importance of psychosocial factors to better understand the process by which children and young people commit crimes as serious as serial murders. The scope of the problem of serial murders perpetrated by minors is controversial because it often depends on how the number of real cases is counted. Although official statistics indicate the low prevalence of juvenile serial killers, childhood is a period in which antisocial behaviour can have its beginning. Some authors consider that it is not uncommon for the first murder of this type to occur in adolescence. It is important to consider psychopathy as an influential factor in the various forms of serial criminal conduct committed by children and young people. The research works consulted provide evidence of the special relevance of psychopathy in the generation of serious juvenile delinquency.

Descripción clínica de los pacientes con amputación transfemoral unilateral: estudio de casos múltiples / Clinical Description Of Patients With Unilateral Transfemoral Amputation

Introducción: Una correcta evaluación fisioterapéutica permite direccionar una intervención idónea del paciente con amputación transfemoral. Objetivo: Describir clínicamente a los pacientes con amputación transfemoral unilateral en la ciudad de Pasto, Nariño, Colombia. Métodos: Se realiza estudio transversal de casos múltiples. Se selecciona una muestra de 13 pacientes que se encontraban en la base de datos del Instituto Departamental de Salud de Nariño, con amputación transfemoral unilateral, a los que se realizó una caracterización sociodemográfica y clínica, así como una evaluación fisioterapéutica. Se obtuvieron valores de frecuencias y porcentajes. El análisis de los datos recolectados se realizó mediante el software SPSS, versión 24. De manera descriptiva se dieron a conocer los resultados de la evaluación fisioterapéutica. Resultados: La edad media de los pacientes fue de 46 años, predominó el género masculino (77 por ciento), y la etiología traumática (69,23 por ciento). La sensación y dolor de miembro fantasma se presentó en el 69,23 por ciento y 53,84 por ciento de los pacientes, respectivamente. Se encontró una disminución marcada de fuerza muscular en los músculos pelvitrocantéreos, glúteo medio, menor y tensor de la fascia lata. El rango de movimiento estaba disminuido para los movimientos de rotación interna con una media de 27,8°/ 45°, rotación externa con una media de 29,8°/ 45° y aducción de cadera con una media de 31,2°/ 45°. Conclusiones: Las principales características clínicas y resultados de evaluación fisioterapéutica de los pacientes con amputación transfemoral unilateral son la presencia de sensación y dolor de miembro fantasma, diminución de fuerza, rangos de movimiento y presencia de escoliosis dorsales y/o lumbares. Realizar un adecuado proceso de evaluación fisioterapéutica, proporciona información sobre las necesidades individuales de cada paciente en cuanto a rehabilitación, para posteriormente, ejecutar un tratamiento idóneo(AU)

Introduction: Correct physiotherapeutic evaluation allows directing ideal intervention for the patient with transfemoral amputation. Objective: To clinically describe patients with unilateral transfemoral amputation in the city of Pasto, Nariño, Colombia. Methods: A cross-sectional study of multiple cases is carried out. A sample of 13 patients was selected. They were in the database of the Departmental Institute of Health of Nariño, with unilateral transfemoral amputation, they had underwent a sociodemographic and clinical characterization, as well as a physiotherapeutic evaluation. Frequency values and percentages were obtained. The analysis of the collected data was carried out using the SPSS software, version 24. The results of the physiotherapeutic evaluation were disclosed in a descriptive manner. Results: The mean age of the patients was 46 years, the male gender predominated (77 percent), and the traumatic etiology (69.23 percent). Phantom limb sensation and pain occurred in 69.23 percent and 53.84 percent of the patients, respectively. A marked decrease in muscle strength was found in the pelvitrochanteric, gluteus medius, minimus, and tensor fascia lata muscles. The range of motion was decreased for movements of internal rotation with a mean of 27.8°/45°, external rotation with a mean of 29.8°/45°, and hip adduction with a mean of 31.2°/ 45°. Conclusions: The main clinical characteristics and physiotherapeutic evaluation results of patients with unilateral transfemoral amputation are the presence of phantom limb sensation and pain, decreased strength, range of motion, and the presence of dorsal and/or lumbar scoliosis. An adequate physiotherapeutic evaluation process provides information on the individual needs of each patient in terms of rehabilitation, in order to subsequently execute an ideal treatment(AU)

Behavioral and Emotional Difficulties and Personal Wellbeing of Adolescents in Residential Care.

This work studies the emotional and behavioural difficulties and the personal wellbeing of adolescents under protective measures. The sample is made up of 151 adolescents in residential care between 11 and 17 years of age. The instruments used were the Strengths and Difficulties Questionnaire (SDQ) and the Personal Wellbeing Index (PWI). The results indicate that a high percentage of adolescents have emotional and behavioural difficulties. We found a greater presence of behavioural rather than emotional problems in the adolescents. Similarly, we also found that females showed more emotional difficulties than the males. As for personal wellbeing, the results indicate that the adolescents are dissatisfied in several areas of their life, they feel insecure and have a pessimistic view of their future and of their achievements. Furthermore, those adolescents who were admitted to residential care due to something other than child abuse have a greater prosocial behaviour. It can be concluded that the more difficulties the adolescents experience (emotional, behavioural and with their peers), the lower the perception of their personal wellbeing will be. This study allows us to design interventions aimed at promoting psychological wellbeing among these adolescents.

Executive Processes and Emotional and Behavioural Problems in Youths Under Protective Measures.

This research studies the executive processes of youths under protective measures between 13 and 18years of age, as well as the emotional problems they have and the presence of behavioural problems, such as difficulties to control and direct attention, to control one's own behaviour and inhibit inadequate or ineffective responses (hyperactivity-impulsiveness) and problems related to emotional regulation. In addition, we study the presence of significant differences according to the sex of the youths. We also analyse to what extent the difficulties in the executive processes are related to and can predict the emotional and behavioural problems. The instruments used were Stroop's Colour and Word Test (Stroop), the Paths Test (TESen), and the System of Evaluation for Children and Adolescents (SENA). The results indicated that the youths had difficulties in such executive processes as execution, speed, and accuracy in carrying out tasks. Furthermore, they had emotion problems, amongst which the symptoms of anxiety are worthy of note; whilst attention deficit, hyperactivity-impulsiveness, and problems related to emotional regulation could also be observed. The data indicated greater difficulties in the executive processes for males than for females. There was a greater emotional symptomatology in the females, whilst there were greater deficits in attention and hyperactivity/impulsiveness in the males. Similarly, the deficits in the executive processes were related to and predicted emotional and behavioural problems. This research suggests the design of a structured programme focused on systematic training in real, daily situations, recommending the use of restorative techniques to work on the affected cognitive skills and techniques aimed at improving the youths' emotion regulation.

Incidencia del perímetro abdominal en la resistencia a esfuerzos intermitentes de universitarios físicamente activos / Incidence of abdominal perimeter in endurance to intermittent efforts by physically active university students

Introducción: El perímetro abdominal y la resistencia a esfuerzos intermitentes, reflejada en el VO2máx, son dos grandes indicadores; el primero del riesgo cardiovascular y el segundo de la capacidad aeróbica máxima. Este estudio permitirá determinar si las mediciones del perímetro abdominal tienen relación con la capacidad del sujeto de responder a esfuerzos intermitentes. Objetivo: Determinar la asociación entre el perímetro de cintura y la resistencia a esfuerzos intermitentes reflejada en el VO2máx. Métodos: Los participantes fueron 91 hombres y 22 mujeres estudiantes de la Licenciatura en Educación Física, Recreación y Deportes de la Universidad de Pamplona. Para la valoración de la resistencia intermitente se empleó el test de fitness intermitente 30-15 (30-15 ITF) con el cual se determinó el VO2máx. Se realizó la toma del perímetro de cintura teniendo en cuenta los criterios de la Federación Internacional de Diabetes. La tabulación y análisis de datos se llevó a cabo en el paquete estadístico PSPP, con la prueba de normalidad de Kolmogorov - Smirnov para hombres y Shapiro - Wilk para mujeres, y el coeficiente correlacional de Spearman (p < 0,05) (valor p de 0,05). Resultados: Se encontró una asociación negativa entre las variables perímetro abdominal e indicador de resistencia a esfuerzos intermitentes VO2máx, en hombres (r = -0,17) y en mujeres (r = 0,09), no obstante, para ambos sexos esta relación no fue estadísticamente significativa (p < 0,05). Conclusión: Se concluye que el perímetro abdominal no está relacionado de forma significativa con la resistencia a esfuerzos intermitentes en universitarios físicamente activos(AU)

Introduction: The abdominal perimeter and endurance to intermittent efforts reflected in VO2max are two major indicators; the first for cardiovascular risk and the second for maximum aerobic capacity. This study will make it possible to determine whether abdominal perimeter measurements are related to the subject's ability to respond to intermittent efforts. Objective: Determine the association between the abdominal perimeter and the endurance to intermittent efforts reflected in the VO2max. Methods: The participants were 91 men and 22 female students of the Bachelor's Degree in Physical Education, Recreation and Sports of the University of Pamplona. For the assessment of intermittent endurance, the intermittent fitness test 30-15 (30-15 ITF) was used with which the VO2max was determined. The abdominal perimeter was taken taking into account the criteria of the International Diabetes Federation. The tabulation and analysis of data was carried out in the PSPP statistical package, applying the Kolmogorov-Smirnov normality test for men and Shapiro-Wilk for women, and, Spearman's correlational coefficient (p < 0,05) (p-value of 0,05). Results: A negative association was found between the variables abdominal girth and the indicator of endurance to intermittent efforts VO2max, in men (r = -0,17) and in women (r = 0,09), however, for both sexes, this relationship was not statistically significant (p < 0,05). Conclusion: It is concluded that, the abdominal perimeter is not significantly related to resistance to intermittent efforts in physically active university students(AU)

Suicidal Ideation and Mental Health: The Moderating Effect of Coping Strategies in the Police Force.

The suicide rate in the police force (Fuerzas y Cuerpos de Seguridad-FFCCSS) is estimated to be greater than that of the general population. The objectives of this paper are to detect mental health problems, in particular depression and anxiety, and to analyze the moderating effect of coping strategies on the relation between mental health and suicide ideation in police officers. The Suicidal Behavior Questionnaire (SBQ-R), Beck's Depression Inventory (BDI), the Anxiety Inventory (STAI), and the Brief Cope have all been used in the study. The sample consists of 98 Spanish police officers, of whom 91.8% were male. The results indicate that depression and anxiety can predict suicidal ideation. Nevertheless, it must be said that coping strategies do not have a moderating effect in the relation between mental health and suicidal ideation in this professional group.

Evaluación de la carga interna en una sesión de entrenamiento funcional de alta intensidad: estudio de casos múltiples / Evaluation of internal load in a high intensity functional training session: multiple case study

Introducción: El entrenamiento funcional de alta intensidad se encuentra en auge por los múltiples beneficios que provee, no obstante, aún son escasos los estudios que permitan la evaluación de la carga interna en esta modalidad. Objetivo: Evaluar la carga interna en una sesión de entrenamiento funcional de alta intensidad en sujetos entrenados. Método: Participaron 10 personas (5 hombres y 5 mujeres) capacitadas en el entrenamiento funcional de alta intensidad, que desarrollaron una sesión de entrenamiento del día compuesta por tres ejercicios del día o work of day. En cada work of day se registraba el tiempo parcial de cada ejercicio (work of day) y la percepción subjetiva del esfuerzo para calcular la carga interna de entrenamiento. El análisis estadístico se realizó con el paquete estadístico PSPP (p-valor de 0,05) aplicando la prueba de la U de Mann-Whitney y la de Wilcoxon para identificar diferencias entre las cargas internas obtenidas por géneros y grupos de experiencia. Resultados: La carga interna manejada para la sesión por mujeres y hombres fue de 253,20 y 242,46 unidades arbitrarias, respectivamente. No existieron diferencias en la carga interna al comparar por géneros y grupos de experiencia en el work of day de forma parcial y total (p > 0,05). Conclusiones: Una sesión de entrenamiento funcional de alta intensidad basada en bloques de entrenamiento de menor tiempo posible representó una carga interna muy dura para sujetos capacitados en esta modalidad(AU)

Introduction: High intensity functional training is on the rise due to the multiple benefits it provides, although there are still few studies that allow the evaluation of the internal load in this modality. Objective: To evaluate the internal load in a high intensity functional training session in trained subjects. Method: Ten subjects participated (5 men and 5 women) trained in high intensity functional training, who developed a training session of the day consisting of three exercises. We registered the part time of each day work and the subjective perception of effort was recorded to calculate the internal training load. Statistical analysis was performed with PSPP statistical package (p-value of 0.05) applying Mann-Whitney U test and Wilcoxon test to identify differences between the internal loads obtained by genders and experience groups. Results: The internal load handled for the session by women and men, was 253.20 and 242.46 arbitrary units, respectively. There were no differences in the internal load when comparing by genders and groups of experience in the day work partially and totally (p> 0.05). Conclusions: A high intensity functional training session based on training blocks for the shortest possible time represented a very hard internal load for subjects trained in this modality(AU)

Bibliotherapy as a Non-pharmaceutical Intervention to Enhance Mental Health in Response to the COVID-19 Pandemic: A Mixed-Methods Systematic Review and Bioethical Meta-Analysis.

Background: A non-pharmaceutical treatment offered as psychological support is bibliotherapy, which can be described as the process of reading, reflecting, and discussing literature to further a cognitive shift. The coronavirus disease 2019 (COVID-19) pandemic demands a response to prevent a peak in the prevalence of mental health problems and to avoid the collapse of mental health services, which are scarce and inaccessible due to the pandemic. Thus, this study aimed to review articles on the effectiveness of bibliotherapy on different mental health problems. Methods: A systematic review was conducted to examine relevant studies that assess the effectiveness of bibliotherapy in different clinical settings as a treatment capable of enhancing a sense of purpose and its surrounding values. To achieve this, a systematic review, including a bioethical meta-analysis, was performed. A variant of the PICO (Participants, Intervention, Comparison, and Outcome) model was used for the search strategy, and the systematic review was conducted in three databases: PubMed, Bireme, and OVID. Inclusion criteria were relevant studies that included the keywords, excluding documents with irrelevant topics, studies on subjects 15 years or younger, and in languages besides Spanish or English. Starting with 707 studies, after three rounds of different quality criteria, 13 articles were selected for analysis, including a hermeneutic analysis, which was followed by a fourth and final recovery round assessing bibliotherapy articles concerning healthcare workers. Results: Our findings showed that through bibliotherapy, patients developed several capacities, including the re-signification of their own activities through a new outlook of their moral horizon. There are no research road maps serving as guides to conduct research on the use of bibliotherapy to enhance mental health. Additionally, values such as autonomy and justice were closely linked with positive results in bibliotherapy. This implies that bibliotherapy has the potential to have a positive impact in different settings. Conclusions: Our contribution is to offer a road map that presents state-of-the-art bibliotherapy research, which will assist institutions and healthcare professionals to plan clinical and specific interventions with positive outcomes.