ABSTRACT
PURPOSE: To describe a case of steroid-induced ocular hypertension in which a clinical significant increase in intraocular pressure resulted with a corresponding corneal hysteresis decreased response. METHOD: A case report is presented in which a 62-year-old white male who was diagnosed with rosacea meibomitis and treated with topical antibiotic steroid combination ointment responded such. CONCLUSION: This case report illustrates a reverse model of the topical antiglaucoma medication studies recently described of decrease in intraocular pressure with an increase in corneal hysteresis with the application of topical prostaglandins and beta-blocker compounds. This may provide additional insight into how the biomechanical properties of the cornea and tunics of the eye respond to local applications of different ocular medications.
Subject(s)
Cornea/physiopathology , Dexamethasone/adverse effects , Glucocorticoids/adverse effects , Ocular Hypertension/physiopathology , Anti-Bacterial Agents/therapeutic use , Dexamethasone/therapeutic use , Drug Combinations , Glucocorticoids/therapeutic use , Humans , Male , Middle Aged , Ocular Hypertension/chemically induced , Tobramycin/therapeutic useABSTRACT
PURPOSE: Several reports have revealed a difference in various populations regarding the variability of intraocular pressure (IOP) and corneal hysteresis (CH). This retrospective study was created to determine a profile for U.S. Veterans in a large outpatient clinical setting. OVERVIEW AND METHODOLOGY: The objective was to evaluate a random cohort of patient records in this clinical setting to determine the mean and standard deviation (SD) of the following parameters: Goldmann-correlated IOP (IOPg), CH, waveform score, and central corneal thickness from the Reichert Ocular Response Analyzer. RESULTS: All patient records were reviewed by Veteran Health Affairs Eye clinical staff which resulted in data collected on 538 eyes. The mean IOP of this cohort for IOPg was 17.39 (SD 10.08). The mean for CH was calculated at 9.61 (SD 3.04) with a waveform score mean of 5.66 (SD 2.18) and central corneal thickness for 207 eyes was a mean of 545.09 (SD 51.09) nm. CONCLUSION: From the results, IOPg appears to be significantly higher and CH significantly lower than other populations reported in the literature. This information provides an accurate baseline for the evaluation of the U.S. veteran population for future.
Subject(s)
Corneal Diseases/epidemiology , Hypesthesia/epidemiology , Intraocular Pressure/physiology , Veterans , Aged , Corneal Diseases/physiopathology , Epidemiologic Studies , Female , Humans , Hypesthesia/physiopathology , Male , Medical Audit , Middle Aged , United States/epidemiologyABSTRACT
PURPOSE: To describe a case of primary open angle glaucoma (POAG) and to illustrate a new principle in detecting and managing the disease using intraocular pressure (IOP) corneal hysteresis as a clinical guide. METHOD: A case report is reviewed of a white 87-year-old male who was detected with ocular hypertension (OHTN) with bilateral asymmetrical corneal stiffness and POAG. CONCLUSION: A new indicator and alternative approach to determine and manage POAG is presented using evidence-based technology for clinical care and facilitating positive outcomes for one of the leading causes of blindness in the world.
