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1.
Eur J Obstet Gynecol Reprod Biol ; 127(1): 115-22, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16815473

ABSTRACT

OBJECTIVE: To assess the level of patient satisfaction after transcervical endometrial resection (TCRE) with no preoperative hormonal preparation. STUDY DESIGN: A retrospective audit of a continuous case series was accomplished on 131 consecutive patients who underwent TCRE for dysfunctional uterine bleeding. Data of postal questionnaires were analysed and subjected to survival analysis. RESULTS: Thirty-three cases were lost to follow-up; thus, the data on 98 of the 131 (74.8%) patients were analysed. The average follow-up period was 94.8 months (60-132). Twenty (20.4%) women required D&C and 15 (15.3%) had hysterectomy. In eight of the 15 cases, the indication for hysterectomy was not related with the primary operation. The chance of avoiding hysterectomy reached a plateau after 72 months, at 78.3% (SE: 5.05%). The chance of avoiding D&C at up to 36 months was 98.6% (SE: 1.4%), and reached a plateau after 107 months at 67.11% (SE: 6.1%); 55.8% of the patients became amenorrhoeic, the remaining cases reporting good improvements in the amount and duration of bleeding, and dysmenorrhoea. Eighty-six of the 98 patients (88%) were satisfied or very satisfied with the result. CONCLUSIONS: TCRE affords reasonable long-term effectiveness in the treatment of dysfunctional uterine bleeding, even without any preoperative hormonal endometrial preparation.


Subject(s)
Endometrium/surgery , Hormone Replacement Therapy , Hysterectomy , Adult , Aged , Female , Follow-Up Studies , Humans , Metrorrhagia/surgery , Middle Aged , Preoperative Care , Reoperation , Retrospective Studies , Surveys and Questionnaires , Treatment Outcome
2.
Hum Reprod ; 21(4): 1047-51, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16410337

ABSTRACT

BACKGROUND: To learn more about the obstetric outcome after initial septum resection and remnant septum (< or =1 cm) resection. METHODS: In 94 patients with septate uteri who underwent uterine septum resection, the reproductive efficiency was analysed in a prospective observational study. The reproductive outcome was analysed after initial resection and (if required) consecutive procedures. RESULTS: A total of 94 women were enrolled in the study; all had had two or more miscarriages. The septum was completely removed during the first hysteroscopy in 58 (62%) cases. A residual septum was observed in 36 (38%) patients. Subsequent operative hysteroscopy was performed in the cases (29/36; 80.5%) involving repeated miscarriage and unsuccessful conception. The minimum observation time was 24 months. The difference in delivery rate after the first hysteroscopy between those with a normalized uterine cavity (26/58; 44.8%) and those with remnants (7/36; 19.4%) was statistically significant (P < 0.05). In fact, following the normalization of the uterine cavity, 62.1% (18/29) of the patients delivered, as compared with 19.4% of those (7/36) with a residue and Kaplan-Meyer curves revealed a statistically significant difference (P < 0.05). CONCLUSIONS: Women with a remnant uterine septum have an increased chance of successful pregnancy with an improved obstetric outcome after normalization of the uterine cavity.


Subject(s)
Infertility, Female/surgery , Maternal Age , Uterus/surgery , Abortion, Spontaneous , Adult , Female , Humans , Pregnancy , Pregnancy Outcome , Uterus/abnormalities , Uterus/pathology
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