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1.
Diagn Cytopathol ; 44(11): 926-930, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27432164

ABSTRACT

Superficial CD34-positive fibroblastic tumor is a low-grade mesenchymal neoplasm of superficial soft tissues characterized by fascicles of spindle to epithelioid cells displaying nuclear pleomorphism and strong diffuse CD34 immunoreactivity. The intraoperative imprint cytology preparations (ICP) of a superficial CD34-positive fibroblastic tumor from a 50-year-old female are described. To the best of our knowledge, there is no report of the cytologic findings of superficial CD34-positive fibroblastic tumor in the English medical literature. The ICP, differential diagnosis, tissue correlation, and ancillary studies of this fascinating entity are discussed. Diagn. Cytopathol. 2016;44:926-930. © 2016 Wiley Periodicals, Inc.


Subject(s)
Antigens, CD34/metabolism , Biomarkers, Tumor/metabolism , Neoplasms, Fibrous Tissue/pathology , Soft Tissue Neoplasms/pathology , Antigens, CD34/genetics , Biomarkers, Tumor/genetics , Diagnosis, Differential , Female , Humans , Middle Aged , Neoplasms, Fibrous Tissue/diagnostic imaging , Neoplasms, Fibrous Tissue/metabolism , Soft Tissue Neoplasms/diagnostic imaging , Soft Tissue Neoplasms/metabolism
2.
Diagn Cytopathol ; 44(5): 422-5, 2016 May.
Article in English | MEDLINE | ID: mdl-26798976

ABSTRACT

Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland malignancy with variable cytologic findings. Its rarity, variable morphologic findings, and similarities with more common salivary gland entities make it a difficult cytologic diagnosis. As the name signifies, the key feature of this tumor is presence of an epithelial and myoepithelial component. However, when one of these two components is scant on the fine needle aspiration (FNA) smears, it may be overlooked. We present a case from a 62 year-old female who presented to the clinic with a parotid nodule and episodes of sharp, throbbing pain. A fine needle aspiration was performed which revealed a highly cellular specimen comprised primarily of aggregates of cells with small, round nuclei and scant to absent cytoplasm. Abundant hyaline stromal material was also noted. The case was signed out as basaloid neoplasm with a recommendation for surgical resection. The subsequent resection specimen revealed EMC. By reviewing the FNA specimen following the surgical resection of the tumor, we were able to utilize the benefit of hindsight to more clearly identify the subtle, biphasic components of the tumor.


Subject(s)
Carcinoma/pathology , Parotid Neoplasms/pathology , Biopsy, Fine-Needle , Cell Nucleus/pathology , Cytoplasm/pathology , Female , Humans , Middle Aged , Stromal Cells/pathology
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