Subject(s)
Gene Frequency , Genes, Dominant , Retinitis Pigmentosa/genetics , Female , Genetic Counseling , Humans , Male , YugoslaviaABSTRACT
We treated 12 eyes with advanced neovascular glaucoma with a modification of drainage implant surgery. All 12 eyes had rubeosis iridis and severe pain and nine had undergone previous glaucoma surgery. After follow-up periods of two to 24 months (mean, 11.3 months), nine of 12 eyes had intraocular pressures of less than 24 mm Hg (mean preoperative value, 49.5 +/- 8.2 mm Hg; mean postoperative value, 22.2 +/- 12.9 mm Hg). Surgery was unsuccessful in three eyes, in two because the anterior chamber remained flat postoperatively and in one because a large hyphema blocked the tube 15 months postoperatively. Our procedure, which uses a Y-shaped Teflon tube, is easy to perform, is well tolerated by the eye, and is associated with a low risk of serious complications.
Subject(s)
Drainage/methods , Glaucoma/surgery , Neovascularization, Pathologic/surgery , Follow-Up Studies , Glaucoma/physiopathology , Humans , Intraocular Pressure , Prostheses and ImplantsABSTRACT
In clinical and in vitro conditions, the effect of intravitreously injected silicone oil upon the electroretinogram and electrooculogram was investigated. The recorded potentials were lower in the eyes with silicone oil compared to those in which the retinas were reattached without silicone. Retinal changes, caused by the previously existing detachment and the operations already performed, are discussed as possible factors responsible for lower values of the recorded potentials. No arguments could be found in favor of silicone retinopathy.
Subject(s)
Electrooculography , Electroretinography , Retinal Detachment/physiopathology , Silicones/administration & dosage , Animals , Electrooculography/methods , Electroretinography/methods , Humans , Injections , Retina/physiology , Retinal Detachment/surgery , Swine , Vitreous BodyABSTRACT
The amplitude and the light rise of the standing potential of the eye were measured in a group of 20 male and 10 female health young subjects. The basic value itself, if measured in the steady state, has a variability not far from its light rise, so it can also be applied clinically. The median base value in our group was 362 microV, with normal limits of 233 and 680 microV. If the light rise is calculated in relation to its basic level, the variability of such a ratio is lower than the variability of the light peak/dark trough ratio. The mean value of our ratio wa 2.19 with a lower limit of 1.57. Maximal normal difference between two eyes of the same subject was 122 microV for the basic value, and 0.45 for the ratio.
Subject(s)
Electrooculography , Evoked Potentials, Visual , Adult , Dark Adaptation , Female , Humans , Light , Male , Photic Stimulation , Reference ValuesABSTRACT
This study examined the effects of clozapine on sleep-wakefulness profile in cats prepared for chronic recording of sleep. Clozapine in single dose (i.p.) of 5 mg/kg drastically reduced slow-wave sleep (SWS) and paradoxical sleep (PS), while wakefulness and drowsy pattern were increased. These changes lasted approximately 24 h and were followed by sleep recovery. PS had a priority of recovery. Some similarities between clozapine effects on sleep in cat and human were mentioned.
