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Ophthalmol Clin North Am ; 18(4): 561-7, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16314219

ABSTRACT

Anti-VEGF therapy is a promising new avenue for the treatment of ocular neovascular diseases. Early preclinical data and recent clinical data support the efficacy and safety of several novel anti-VEGF for NVAMD. Whether these novel biologics are used on their own, in combination with previously available therapies, or with newly developing therapies, they represent a new avenue in treatment. These agents are highly selective in their targeted approaches, and when administered appropriately , offer treatment with minimal damage to retinal tissue. In the future, biotherapeutic agents will certainly play a powerful role in the treatment of human choroidal neovascular membrane formation.


Subject(s)
Angiogenesis Inhibitors/therapeutic use , Macular Degeneration/drug therapy , Photochemotherapy/methods , Photosensitizing Agents/therapeutic use , Humans , Macular Degeneration/metabolism , Macular Degeneration/pathology , Treatment Outcome , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Vascular Endothelial Growth Factor A/metabolism
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