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Int J Periodontics Restorative Dent ; 28(3): 239-43, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18605599

ABSTRACT

A report of a patient who presented with severe disfigurement of the maxillary left lateral incisor and canine area following oncologic surgery is presented. The bone defect extended 20 mm from the cervical line of adjacent teeth up to and including the nasal cavity. Treatment was performed with a 1:1 ratio of autogenous bone graft (harvested from the retromolar region) and deproteinized bovine bone particles. The composite graft was hydrolyzed with recombinant human platelet-derived growth factor BB and covered with a titanium-reinforced nonresorbable membrane. Second-stage surgery was performed at 6 months, at which point the membrane was removed and two titanium dental implants were successfully placed. The elapsed time from initial surgery to definitive prosthesis placement was 14 months.


Subject(s)
Alveoloplasty/methods , Angiogenesis Inducing Agents/therapeutic use , Guided Tissue Regeneration, Periodontal/methods , Platelet-Derived Growth Factor/therapeutic use , Adult , Becaplermin , Bone Matrix/transplantation , Bone Substitutes/therapeutic use , Bone Transplantation/methods , Dental Implants , Dental Prosthesis, Implant-Supported , Female , Follow-Up Studies , Humans , Maxilla/surgery , Maxillary Diseases/surgery , Membranes, Artificial , Minerals/therapeutic use , Polytetrafluoroethylene , Proto-Oncogene Proteins c-sis , Recombinant Proteins , Titanium
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