ABSTRACT
Secretory breast carcinoma was first described by McDivitt and Stewart in 1966, who reported seven cases of this tumoural strain in children and therefore named it "juvenile carcinoma". However, a couple of decades later, Tavassoli and Norris reported a series of 19 cases and found that most occurred in adults, and therefore they proposed changing its name to "secretory carcinoma." Since then, approximately 100 cases have been reported in the world literature. We present two cases treated with total mastectomy and sentinel node biopsy with excellent outcome. To our knowledge, only a few cases have been reported in Latin American patients
El carcinoma secretor dela mama fue inicialmente descrito por McDivitt y Stewartin en 1966, en su artículo, siete casos de este tipo de tumor se presentaron en niños, por lo tanto, se le asignó el nombre de "carcinoma Juvenil", pero un par de décadas después Tavassoli y Norris encontraron en su serie de 19 casos, que la mayoría eran adultos, y así propusieron cambiar el nombre a Carcinoma secretor. Desde ese momento aproximadamente 100 casos han sido reportados en la literatura. Nosotros presentamos dos casos tratados con mastectomía y ganglio centinela, con excelente pronóstico. Hasta donde sabemos, esta patología se ha reportado escasamente en pacientes latino americanos
Subject(s)
Humans , Female , Middle Aged , Aged , Breast Neoplasms/pathology , Mastectomy/methods , Sentinel Lymph Node Biopsy/methods , Neoplasm Invasiveness/pathologyABSTRACT
BACKGROUND: Adamantinoma is a rare lesion of low-grade malignancy, and represents 1% of malignant bone tumours of bones, and is mainly located in two regions of the body, jaw (ameloblastoma), and lower extremities. The treatment of choice is surgery due to it being a radio- and chemotherapy-resistant neoplasia. CLINICAL CASE: A 39 year old male with a history of neonatal hydrocephalus with moderate psychomotor retardation. He began with pain in the posterior region of the left thigh for one year before admission, which was managed as posterior radicular syndrome. He had sudden intense pain on walking, that led him to fall over. In the examination, left pelvic limb with deformity in the distal third with increase in volume in the thigh, with pain to palpation, and presence of crackles in the distal third of the femur. A biopsy of the thigh was performed, with subsequent local wide excision + replacement of bone with cadaver bone and a central medullary nail. The final diagnosis was adamantinoma of femur. CONCLUSION: The adamantinomas are rare tumours. It is important to recognise this type of tumor from the beginning, since its prognosis is excellent in initial stages. It is important to have free margins as survival is very high.
