[Rare complications in polycystic kidney--the difficulties in their diagnosis and treatment]. / Redki uslozhneniia na bubrechnata polikistoza--trudnosti pri diagnostikata i lechenieto im.

The development of some rare complications of renal polycystosis is discussed. Four patients with chronic polycystosis with complications are followed up. In 3 of them (2 of them on chroniodialysis) the cysts suppurated and after an infective conservative treatment they were treated surgically-puncture, cyst excision and unilateral nephrectomy. To the fourth patient bilateral nephrectomy had been performed 5 years ago because of other reasons. All 4 patients are alive at present with a fairly good end result.

[Secondary cystic changes in the kidneys in chronic kidney failure]. / Vtorichni kistozni izmeneniia v bubretsite pri khronichna bubrechna nedostatuchnost.

In patients with chronic renal failure the presence and frequency of acquired cystic changes in the kidneys (acquired cystic renal disease) were studied. 46 patients, 21 to 62 years of age and duration of hemodialysis treatment from 2 up to 126 months, were examined. The patients with polycystic kidneys were excluded. Cysts were found in 67.4% of the patients. They were classified into five groups. Between the duration of the hemodialysis treatment (the chronic renal failure respectively) and the development of the cystic renal disease correlation was found. The correlation between the length of the kidneys and the cystic changes is statistically significant. There is no correlation with the sex, age, basic disease, hematologic indices, diuresis and arterial pressure of the patients. In 50% of the patients examined splenomegaly was found the cause of which is not known.

[Chronic pyelonephritis in polycystic kidney]. / Kum problema za khronichniia pielonefrit pri bubrechna polikistoza.

The characteristics of chronic pyelonephritis are studied in 37 patients out of a total of 53 patients with proved renal polycystosis. A group of 71 patients with chronic pyelonephritis selected at random are used as a control group. The frequency of chronic pyelonephritis among the patients with renal polycystosis is 69.8%. The difference between the mean age of the patients with renal polycystosis and chronic pyelonephritis and the patients with renal polycystosis without chronic pyelonephritis is 8.6 years. A significant difference is established between these two groups of patients concerning the frequency of symptomatic hypertension--89.2% for the patients with renal polycystosis and chronic pyelonephritis and 45% for the patients with uncomplicated renal polycystosis. A similar difference is established also for the renal failure--respectively 64.9% and 37.5%. The frequency of hypertension and chronic renal failure is lower in the control group of patients. 59% of the patients with renal polycystosis and chronic pyelonephritis have significant bacteriuria, E. coli and Proteus being the most frequently isolated bacteria but Pseudomonas shows the highest drug resistance. The isolated bacteria are most sensitive to nitroxoline and aminoglycoside antibiotics.

[Acute poisoning by tricyclic antidepressants in childhood]. / Ostri otravianiia s niakoi tritsiklichni antidepresanti v detskata vuzrast.

The authors share their experience in the clinical observation and treatment of 72 children with acute intoxications by tricyclic antidepressants. The syndromes, forming the clinical picture of the acute intoxication at that age were the cerebrotoxic, cholinolytic and cardiotoxic ones. According to their content, the intoxication advanced in three forms: light, moderately severe and severe. The complex application of the therapeutic methods from the unified therapeutic system for the treatment of acute intoxications gave lethality of 5.5%, determined, primarily, by the late admittance of the children for hospital treatment in a state of decompensated phase of exotoxic shock. The anamnestic data for administration of tricyclic preparation in toxic and lethal doses is a signal for hospitalization of the chill with the inclusion of all necessary procedures with a dynamic follow up of its state.

[Bone disease in patients undergoing chronic hemodialysis treatment and the role in its development of magnesium in drinking water used in the preparation of dialysis solution]. / Kostna bolest pri bolni na khroniokhemodializno lechenie i roliata na magneziia v piteinata voda, ot koiato se prigotvia dializatniiat raztvor, za razvitieto i.

Studying the role of magnesium on uremic osseous disease in patients on chroniohemodialysis we examined 50 patients with chrovic renal diseases, chronic renal insufficiency (CRI) and chroniodialysis treatment (CDT) with duration of the dialysis treatment from I to 10 years, 3 years on the average, and compared it with control groups of 20 patients with chronic renal diseases without CRI, with duration of the diseases from 3 to 22 years, 9 years on the average and 20 patients with chronic renal diseases and CRI (stage I--III) on conservative treatment, with a duration of the CRI from 0.5 to 6 years, 2 years on the average. The following indices were studied in all patients: serum levels of calcium, phosphorus, magnesium and alkaline phosphatase--montry, to the dialysis patients the samples were taken at the beginning of dialysis séance, and calcium and magnesium content in drinking water used for the preparation of dialysis solution, was twice yearly investigated. In accordance with the bibliographic check up, the bones of all patients adequate for study were photographed with "soft" (mu)-roentgen rays, three times for the observation period, but severe bone changes (osteonecrosis and fractures)--were not established. The level of magnesium in serum of the patients by the end of dialysis séances in the significant group of them was impressive (p less than 0,001).(ABSTRACT TRUNCATED AT 250 WORDS)

[Our experience with the dialysis treatment of phalloides fungal poisoning]. / Nashiiat opit a dializno lechenie na faloidnata gubna intoksikatsiia.

The authors present their practical experience in the treatment of phalloid fungal intoxication via dialysis methods of treatment, included within the complete therapeutic system of that kind exogenous intoxication. The peritoneal dialysis and hemodialysis, with consideration given to the patient's state, enables the reduction of the extremely high lethality. Their early application guarantees higher effectiveness of the dialysis methods of treatment.