ABSTRACT
OBJECTIVES: Understanding the impact on our work place of increasing antibiotic resistance in respiratory infections. MATERIAL AND METHODS: We have performed a retrospective observational study on patients with significant sputum culture admitted to Internal Medicine Service Hospital General in Ciudad Real from January to December 2008. Information has been collected on the epidemiological, microbiological features, resistance patterns and treatment. RESULTS: The total number of patients included in this study was 60. In 83.3% there was a predisposing factor. In 43 cases the diagnosis was made in spring and summer months. The exacerbation of COPD was the most frequent diagnosis (61.7%). The most frequently isolated organism was Pseudomonas spp. (41.7%). In our hospital the most commonly used antimicrobials in the initial treatment are levofloxacin (36.7%) and amoxicillinclavulanate (26.7%). The antibiotics with the highest percentage of antibiotic resistance were ciprofloxacin in E. coli (66.7%) and Pseudomonas spp. (60%), penicillin for S. pneumoniae (100%). CONCLUSIONS: The results of this study demonstrate the significant presence of resistance to most commonly used antibiotics in microorganisms which cause respiratory infections.
Subject(s)
Cross Infection/microbiology , Respiratory Tract Infections/microbiology , Adult , Aged , Aged, 80 and over , Causality , Coinfection , Cross Infection/drug therapy , Cross Infection/etiology , Drug Resistance, Bacterial , Female , Humans , Male , Microbial Sensitivity Tests , Middle Aged , Pulmonary Disease, Chronic Obstructive/complications , Pulmonary Disease, Chronic Obstructive/microbiology , Respiratory Tract Infections/drug therapy , Respiratory Tract Infections/etiology , Retrospective Studies , Seasons , Spain/epidemiology , Sputum/microbiology , Young AdultABSTRACT
Objetivos: Conocer el impacto en nuestro lugar de trabajo del aumento de resistencias antibióticas en las infecciones respiratorias. Material y métodos: Se ha realizado un estudio observacional retrospectivo de los pacientes con cultivo de esputo significativo ingresados en el Servicio de Medicina Interna del Hospital General de Ciudad Real desde enero a diciembre de 2008. Se ha recogido información sobre las características epidemiológicas, microbiológicas, patrones de resistencia y tratamiento. Resultados: Se han incluido un total de 60 pacientes. En el 83,3% existía algún factor predisponente. En 43 de los casos el diagnóstico se hizo en los meses de primavera y verano. La reagudización de la EPOC ha sido el diagnóstico más frecuente (61,7%). El microorganismo más frecuentemente aislado ha sido Pseudomonas spp. (41,7%). En nuestro hospital los antimicrobianos más empleados en el tratamiento inicial son levofloxacino (36,7%) y amoxicilina-clavulánico (26,7%). Los antibióticos con mayor porcentaje de resistencia han sido ciprofloxacino en E. coli (66,7%) y Pseudomonas spp. (60%) y penicilinas en S. pneumoniae (100%). Conclusiones: Los resultados presentados ponen de manifiesto la importante presencia de resistencias de los microorganismos causantes de infecciones respiratorias a los antibióticos de uso más habitual(AU)
Objectives. Understanding the impact on our work place of increasing antibiotic resistance in respiratory infections. Material and methods. We have performed a retrospective observational study on patients with significant sputum culture admitted to Internal Medicine Service Hospital General in Ciudad Real from January to December 2008. Information has been collected on the epidemiological, microbiological features, resistance patterns and treatment. Results. The total number of patients included in this study was 60. In 83.3% there was a predisposing factor. In 43 cases the diagnosis was made in spring and summer months. The exacerbation of COPD was the most frequent diagnosis (61.7%). The most frequently isolated organism was Pseudomonas spp. (41.7%). In our hospital the most commonly used antimicrobials in the initial treatment are levofloxacin (36.7%) and amoxicillinclavulanate (26.7%). The antibiotics with the highest percentage of antibiotic resistance were ciprofloxacin in E. coli (66.7%) and Pseudomonas spp. (60%), penicillin for S. pneumoniae (100%). Conclusions. The results of this study demonstrate the significant presence of resistance to most commonly used antibiotics in microorganisms which cause respiratory infections(AU)