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1.
Sci Rep ; 11(1): 13239, 2021 06 24.
Article in English | MEDLINE | ID: mdl-34168251

ABSTRACT

Area analysis of thermal images can detect delayed healing in diabetes foot ulcers, but not venous leg ulcers (VLU) assessed in the home environment. This study proposes using textural analysis of thermal images to predict the healing trajectory of venous leg ulcers assessed in home settings. Participants with VLU were followed over twelve weeks. Digital images, thermal images and planimetry of wound tracings of the ulcers of 60 older participants was recorded in their homes by nurses. Participants were labelled as healed or unhealed based on status of the wound at the 12th week follow up. The weekly change in textural features was computed and the first two principal components were obtained. 60 participants (aged 80.53 ± 11.94 years) with 72 wounds (mean area 21.32 ± 51.28cm2) were included in the study. The first PCA of the change in textural features in week 2 with respect to week 0 were statistically significant for differentiating between healed and unhealed cases. Textural analysis of thermal images is an effective method to predict in week 2 which venous leg ulcers will not heal by week 12 among older people whose wounds are being managed in their homes.


Subject(s)
Diagnostic Imaging/methods , Varicose Ulcer/diagnostic imaging , Wound Healing , Aged, 80 and over , Female , Humans , Male , Time Factors
2.
Small ; 17(32): e2100621, 2021 08.
Article in English | MEDLINE | ID: mdl-34105241

ABSTRACT

Limited levels of UV exposure can be beneficial to the human body. However, the UV radiation present in the atmosphere can be damaging if levels of exposure exceed safe limits which depend on the individual the skin color. Hence, UV photochromic materials that respond to UV light by changing their color are powerful tools to sense radiation safety limits. Photochromic materials comprise either organic materials, inorganic transition metal oxides, or a hybrid combination of both. The photochromic behavior largely relies on charge transfer mechanisms and electronic band structures. These factors can be influenced by the structure and morphology, fabrication, composition, hybridization, and preparation of the photochromic materials, among others. Significant challenges are involved in realizing rapid photochromic change, which is repeatable, reversible with low fatigue, and behaving according to the desired application requirements. These challenges also relate to finding the right synergy between the photochromic materials used, the environment it is being used for, and the objectives that need to be achieved. In this review, the principles and applications of photochromic processes for transition metal oxides and hybrid materials, photocatalytic applications, and the outlook in the context of commercialized sensors in this field are presented.


Subject(s)
Transition Elements , Ultraviolet Rays , Humans , Oxides
4.
Nat Commun ; 7: 13976, 2016 12 23.
Article in English | MEDLINE | ID: mdl-28008918

ABSTRACT

Achieving small transverse beam emittance is important for high brightness cathodes for free electron lasers and electron diffraction and imaging experiments. Double-gate field emitter arrays with on-chip focussing electrode, operating with electrical switching or near infrared laser excitation, have been studied as cathodes that are competitive with photocathodes excited by ultraviolet lasers, but the experimental demonstration of the low emittance has been elusive. Here we demonstrate this for a field emitter array with an optimized double-gate structure by directly measuring the beam characteristics. Further we show the successful application of the double-gate field emitter array to observe the low-energy electron beam diffraction from suspended graphene in minimal setup. The observed low emittance and long coherence length are in good agreement with theory. These results demonstrate that our all-metal double-gate field emitters are highly promising for applications that demand extremely low-electron bunch-phase space volume and large transverse coherence.

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