[Gastric metastasis of cutaneous melanoma. Apropos of a case letter]. / Métastase gastrique d'un mélanome cutané. A propos d'un cas.

We report a case operated for gastric metastasis of a cutaneous melanoma. Although such localizations are frequent, symptomatology is nonspecific. Diagnostic fibroscopy is effective if the lesion is blackened by melanin. Immediate surgery is required to avoid acute complications. The indication for elective surgery can be raised if there is a solitary metastasis. In case of recurrence, subtotal gastrectomy appears to be possible. Although the prognosis is poor, surgery offers important palliative relief.

[Association of bronchogenic cyst of the pancreas and duplication cyst of the stomach]. / Association d'un kyste bronchogénique du pancréas à un kyste de duplication de l'estomac.

One case of bronchogenic cyst of the pancreas associated to a true gastric cyst produced by duplication is described. Such congenital neoformations are extremely rare. The symptoms are highly variable. The diagnosis can be established only through the histopathological study of the surgical specimen.

[Neurologic risks caused by perinatal and neonatal problems in a provincial hospital]. / Rischio neurologico da problemi perinatali e neonatali in un ospedale di provincia.

The study intends to value results of follow-up of risk neonates hospitalized for the period 1980-88 at Neonatal Intensive Care Unit of Bufalini Hospital Cesena and the course with time of neurologic and neuropsychological alterations, reported to the birth-rate of territory in which operates the Neonatal Intensive Care Unit. The survivor infants attended in follow up have been 419: 63 of neonatal weight less than or equal to 1500 g (group A), 117 of weight 1501-2000 g (group B), 239 of weight greater than 2000 g (group C). The follow-up provided at first 12 months of life a pediatric examination together with motoscopic examination to Milani-Comparetti every two months, at 3 years--4 years and 6 months, 7 years a pediatric examination with evaluation of Intelligence Quotient (N.E.M.I.), at last two months of 1st Primary School evaluation of acquired scholastic learning capacities by reading test of Inizan and calculation test of Meljac. Diagnosis of cerebral palsy (C.P.) has been always placed at first 12 months of life. All the survivors have been executed pediatric checks as foreseen at first 12 months of life. The subjects with CP are 26 (%); of these 13 have an I.Q. less than or equal to 70. The risk to develop CP seems to depend strictly by hypoxic perinatal stress (21/26 infants). The type of CP seems to be conditioned by neonatal weight, in particular as regards spastic paraplegia (10/12 infants of weight less than or equal to 2000 g), but hemiplegia and tetraplegia are with equality distributed (7/14 infants of weight less than or equal to 2000 g).(ABSTRACT TRUNCATED AT 250 WORDS)

Juvenile pilocytic astrocytoma of the optic nerve diagnosed by fine needle aspiration biopsy.

Fine needle aspiration biopsy of an orbital mass was performed under CT guidance in a nine-year-old boy presenting with rapidly increasing proptosis of the right eye with lateral displacement and no light perception. The cytologic findings consisted of bipolar astrocytes with cytoplasmic fibrillated processes intermingled with Rosenthal fibers. A cytologic diagnosis of juvenile pilocytic astrocytoma was advanced; this was confirmed by subsequent histologic study of the surgical specimen. The differential diagnosis among juvenile pilocytic astrocytoma, neurilemmoma and meningioma of the optic nerve are discussed.

[An intra-oral device for orojejunal feeding of low-weight neonates]. / Apparecchio endorale per nutrizione oro-digiunale nel neonato di basso peso.

An intraoral device has been experimented to stabilize oro-gastric or oro-jejunal feeding tubes in low birth weight newborns.

[Juvenile hyaline fibromatosis. Description of a case and review of the literature]. / La fibromatosi ialina giovanile. Descrizione di un caso e revisione della letteratura.

The authors report a typical case of JHF. The complete review of the literature shows that no more than 20 cases have been so far described. The clinical, pathological and electron microscopic features are stressed and the main clinical and pathological differential diagnoses are considered. The disease, formerly thought to be due to an abnormal composition of collagen fibers, seems to be nowadays, thanks to Japanese authors, related to an error in glycosaminoglycans metabolism.

Long-term survival in response to combined chemotherapy and radiotherapy in laryngeal small cell carcinoma.

Fourteen patients with small cell carcinoma of the larynx are studied. This represents the largest series, from a single institution, reported in the literature. This neoplasm is usually highly aggressive and the prognosis very poor, but, in our experience, combined chemo- and radiotherapy can significantly improve the clinical course of the disease. Three of six patients who received this combined modality treatment are still clinically disease-free more than six years after the initial diagnosis.

Analysis of spontaneous deletion mutants of satellite bacteriophage P4.

Spontaneous deletion mutants of satellite bacteriophage P4 have been isolated and characterized. All of the deletions analyzed that were between 850 and 1,700 base pairs long are within the region nonessential for P4 lytic development; some of them cover the cII or the gop locus.

Chondrosarcoma of the larynx: review of the literature and report of three cases.

Three patients with laryngeal chondrosarcoma were observed at the ENT Department of Padua University from 1966 to 1983. Including the present observations, about 150 of these neoplasms have been described in the literature. The male to female ratio was 3:1, and the age at diagnosis ranged from 33 to 91 years (median, 66 years). The rate of metastasis was 8 per cent, and histologically positive lymph nodes developed in only five patients. Surgery is the treatment of choice for laryngeal chondrosarcoma. Radical neck dissection does not appear to be indicated, unless results of clinical examination suggest metastatic lymph nodal involvement.

Chondromyxoid fibroma of the iliac bone: a case report with ultrastructural observations.

Ultrastructural findings in an unusual case of chondromyxoid fibroma are reported. The tumor was located in the iliac bone of a 42-year-old woman with left hip pain of 5 years duration.

Mucoid carcinoma of the breast on fine-needle aspiration biopsy sample: cytology and ultrastructure.

16 cases of mucoid carcinoma of the breast were diagnosed in specimens obtained by fine-needle aspiration biopsy. The subsequent tissue examination confirmed the cytologic diagnosis in all 16 cases but revealed in 1 case an association with an endocrine component and in 3 cases the presence of an invasive ductal component. The diagnostic and prognostic necessity of distinguishing pure forms of mucoid carcinoma from those associated with invasive ductal carcinoma or endocrine differentiation means that investigations other than fine-needle aspiration biopsy are also required. In every case, the cytologic diagnosis of mucoid carcinoma should be considered as an aspect of the tumor and not representative of the entire neoplasm.

[Fat necrosis in the newborn infant associated with hypercalcemia and dyslipidemia (description of a case)]. / Adiponecrosi del neonato associata a ipercalcemia e dislipidemia (descrizione di un caso).

A case of subcutaneous fat necrosis (S.F.N.) with hypercalcemia and hyperlipemia in a newborn infant is reported. On the basis of previous reports it is impossible to definite the pathogenesis of hypercalcemia and hyperlipemia in subcutaneous fat necrosis. Moreover the Authors point out that in a newborn with S.F.N. plasma levels of calcium and lipids and, if it is possible, urinary prostaglandin E and serum PTH and 250HD3 should be determined.