ABSTRACT
Massive upper gastrointestinal (GI) hemorrhage is a rare manifestation of GI cytomegalovirus (CMV) infection. A review of the English language literature yielded 21 well-documented cases of gastric ulcers due to CMV, and 7 of these 21 cases were complicated by significant GI bleeding. This report describes two cases of massive upper GI hemorrhage due to CMV infection in patients with acquired immunodeficiency syndrome (AIDS).
Subject(s)
AIDS-Related Opportunistic Infections/virology , Cytomegalovirus Infections/complications , Gastrointestinal Hemorrhage/etiology , Stomach Ulcer/virology , Adult , Fatal Outcome , Humans , Male , Stomach Ulcer/complications , Stomach Ulcer/pathologyABSTRACT
BACKGROUND/AIMS: This study was made to determine the incidence and natural history of iatrogenic Mallory-Weiss tears. PATIENTS AND METHODS: We retrospectively analyzed twelve cases of iatrogenic Mallory-Weiss tears identified from 2,461 consecutive upper gastrointestinal endoscopies performed at our institution over a period of twenty-two months. RESULTS: In all cases, bleeding stopped spontaneously without the need of blood transfusions, endoscopic hemostasis therapy or any other interventions. Eight patients (67%) had retching or struggling during the procedure. Hiatus hernias were noted in three patients (25%). CONCLUSIONS: Iatrogenic Mallory-Weiss tears are rare and generally have a benign course. They tend to occur mostly in patients who have experienced excessive retching or struggling during endoscopy.
