ABSTRACT
CLINICAL CASE: Seven-year-old male patient, affected by xeroderma pigmentosum (XP) who was referred to ophthalmology due to the presence of numerous tumours in his left eye that affected the eyelids and conjunctiva. He had a tumour in his lower eyelid that affected the free edge, creating a secondary ectropion, and several lesions with a melanocytic appearance in conjunctiva. A resection of the eyelid tumour and the conjunctival lesions were performed by placing a skin graft and amniotic membrane, respectively, as covering. DISCUSSION: XP patients have high probability of developing eye tumours. A thorough ophthalmic examination is necessary to establish an early diagnosis.
Subject(s)
Carcinoma, Basal Cell/surgery , Eyelid Neoplasms/surgery , Eyelids/surgery , Neoplasms, Radiation-Induced/surgery , Plastic Surgery Procedures/methods , Xeroderma Pigmentosum/surgery , Amnion/transplantation , Carcinoma, Basal Cell/etiology , Child , Eyelid Neoplasms/etiology , Humans , Male , Neoplasms, Multiple Primary/etiology , Neoplasms, Radiation-Induced/etiology , Skin TransplantationABSTRACT
Objetivo: Evaluar la efectividad del tratamiento con colirio de suero autólogo al 100% en pacientes con diversas patologías oculares. Métodos Estudio descriptivo, observacional, prospectivo de mayo de 2005 a febrero de 2009. La población del estudio fueron los pacientes que iniciaron tratamiento con colirio de suero autólogo al 100% elaborado en dosis unitarias. Para la evaluación de la efectividad del estudio se valoraron la desaparición o la mejoría de la sintomatología ocular en los pacientes mediante un cuestionario sobre los signos y los síntomas apreciados por el paciente al inicio y al final del tratamiento. Resultados Se evaluó a un total de 15 pacientes (24 ojos). Los síntomas, como el ojo rojo, el ardor o la quemazón, los pinchazos y la pesadez de los ojos, mejoraron en el 100% de los pacientes que los sufrían, mientras que la sensación del ojo seco y la arenilla mejoraron en el 92% de los casos. Para el 66,7% de los pacientes evaluados la mejoría en los síntomas justificó la incomodidad por la extracción de sangre. Con respecto a la tolerancia del colirio al 100%, solo un paciente presentó alguna molestia relacionada con la instilación del colirio. Conclusión La utilización de colirio de suero autólogo al 100% se asoció a una mejoría de la sintomatología ocular en la mayoría de los pacientes evaluados(AU)
Objective: To evaluate the effectiveness of 100% autologous serum eye drops for the treatment of various ocular surface disorders. Methods: A descriptive prospective observational study carried out from May 2005 to February2009 which included patients with ocular surface disorders treated with single-dose autologous serum eye drops. Treatment effectiveness was evaluated by using a clinical questionnaire inorder to assess symptoms experienced by patients at the beginning and end of treatment. Results: A total of 15 patients (24 eyes) were evaluated. Clinical symptoms such as redness, burning, sharp pain and tired eyes improved in 100% of the patients, whereas dryness and sandy/gritty sensation improved in 92% of the patients. The overall improvement of clinical symptoms was worth the inconvenience of venipuncture according to 66.7% of the patients. Regarding tolerance for autologous serum eye drops, only one patient experienced some discomfort when using the single-dose eye drops. Conclusion: The treatment with 100% autologous serum eye drops improved ocular symptoms for most patients (AU)
Subject(s)
Humans , Ophthalmic Solutions/pharmacokinetics , Serum , Eye Diseases/drug therapy , Prospective StudiesABSTRACT
OBJECTIVE: To evaluate the effectiveness of 100% autologous serum eye drops for the treatment of various ocular surface disorders. METHODS: A descriptive prospective observational study carried out from May 2005 to February 2009 which included patients with ocular surface disorders treated with single-dose autologous serum eye drops. Treatment effectiveness was evaluated by using a clinical questionnaire in order to assess symptoms experienced by patients at the beginning and end of treatment. RESULTS: A total of 15 patients (24 eyes) were evaluated. Clinical symptoms such as redness, burning, sharp pain and tired eyes improved in 100% of the patients, whereas dryness and sandy/gritty sensation improved in 92% of the patients. The overall improvement of clinical symptoms was worth the inconvenience of venipuncture according to 66.7% of the patients. Regarding tolerance for autologous serum eye drops, only one patient experienced some discomfort when using the single-dose eye drops. CONCLUSION: The treatment with 100% autologous serum eye drops improved ocular symptoms for most patients.