ABSTRACT
Three new cases of diffuse pulmonary lymphangioleiomyomatosis are presented. Case number 1 is a female patient who presented repeated pneumotorax and dyspnea without evidence by CT scan and gynecological ultrasound of extrathoracic lesions. This patient did not respond to medroxiprogesterone and died 5 years after the initial diagnosis having suffered chronic, severe, global respiratory failure for 4 years. Case number 2 is a female patient who presented dyspnea, chyloptysis and chylothorax, with iliac, paraaortic and mediastinic lymphangioleiomyomas. The last time she was seen, she was still alive after 6 years without treatment. Case number 3 presented lymphangioleiomyomatosis associated to undifferentiated breast carcinoma. The evolution was apparently slow probably because it was diagnosed 14 years after menopause, and died due to a relapse of the neoplasia. All three patients had radiographic images and respiratory functional studies characteristic of this disease and diagnosis was confirmed by biopsy. The literature is reviewed.
Subject(s)
Lung Neoplasms , Lymphangiomyoma , Lymphoproliferative Disorders , Adult , Aged , Female , Humans , Lung Neoplasms/complications , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/pathology , Lung Neoplasms/physiopathology , Lung Neoplasms/therapy , Lymphangiomyoma/complications , Lymphangiomyoma/diagnostic imaging , Lymphangiomyoma/pathology , Lymphangiomyoma/physiopathology , Lymphangiomyoma/therapy , Lymphoproliferative Disorders/complications , Lymphoproliferative Disorders/diagnostic imaging , Lymphoproliferative Disorders/physiopathology , Middle Aged , RadiographyABSTRACT
Sleep apnea syndrome is a condition which may be related to mandibular hypoplasia of a congenital as well as developmental nature. It is extremely unusual in adults; however, a case of sleep apnea syndrome gradually developing in an adult patient is illustrated in this report. Correction by means of maxillary and mandibular osteotomies was indicated.
