1.
Bioorg Med Chem Lett
; 20(6): 1994-2000, 2010 Mar 15.
Article
in English
| MEDLINE
| ID: mdl-20167488
ABSTRACT
Discovery efforts were focused on identifying a non-nucleoside antiviral for treating infections caused by human cytomegalovirus (HCMV) with equal or better potency and diminished toxicity compared to current therapeutics. This Letter describes the HCMV DNA polymerase inhibition and in vitro antiviral activity of various 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides.