ABSTRACT
BACKGROUND: Mycobacterium gastri is an atypical non pigmented mycobacteria infrequent in clinical practice. Few reports have been published about infections caused by microorganism, and only three of them, all before 1986, were respiratory infections. METHODS: We report a case of cavitary pneumonia with sputum culture positive for Mycobacterium gastri, and we review the previous published cases. RESULTS: We describe a 79-years old man diagnosed of chronic obstructive pulmonary disease (COPD), with chronic respiratory failure, hypertension, Alzheimer's disease and multiple myeloma IgG lambda type IIA, with multiple previous admissions in our institution. He has again admitted because of an acute episode of cough and fever. The chest radiography demonstrated a right lower cavitary infiltrate, and the sputum culture showed growth of Mycobacterium gastri. DISCUSSION: We report a case of cavitary pneumonia in an immunocompromised patient caused by M. gastri resistant to isoniazid and pyrazinamide with fatal evolution. All of the cases previously described had a favourable outcome with the different treatment used.
Subject(s)
Nontuberculous Mycobacteria/isolation & purification , Pneumonia, Bacterial/microbiology , Sputum/microbiology , Aged , Humans , MaleABSTRACT
Objetivos: Analizar las características de los pacientes diagnosticados de CCRM en el área sanitariade León, el impacto sobre la supervivencia y las posibles variables pronósticas.Material y métodos: Utilizando los datos del Registro de Tumores del Hospital de León se hananalizado las características de aquellos pacientes con tumores colo-rectales diagnosticados entre 1993y 2002, clasificándolos dos grupos: el primero constituido por 74 pacientes diagnosticados de CCRMy el segundo formado por 1342 pacientes con tumores únicos diagnosticados en el bienio 1996-1997.Resultados: La frecuencia de CCRM fue del 2,7%. La edad de los pacientes con CCRM fue 2años mayor con respecto a la de los pacientes con neoplasias únicas, con una elevada proporción(38%) de antecedentes familiares oncológicos en familiares de primer grado. No se observaron diferenciassignificativas en cuanto a la localización y el estadio del primer tumor colo-rectal con respectoal grupo de tumores únicos. La supervivencia de los pacientes con CCRM metacrónico fue netamenteinferior, posiblemente en relación con un mayor número de segundas neoplasias diagnosticadas en estadiostempranos en los pacientes con CCRM sincrónico. Las variables que influyeron en el pronósticofueron la edad, el sexo, y el padecimiento de un CCRM sincrónico o metacrónico.Conclusiones: El CCRM es una entidad frecuente en nuestro medio. La tasa de antecedentes familiaresoncológicos en estos pacientes es muy elevada. No se encontraron diferencias significativasen cuanto al pronóstico de estos pacientes respecto al de los pacientes con neoplasias únicas
Purpose: We analyze the characteristics of patients with multicentric colo-rectal cancer (MCRC)in the health district of León, the impact on survival, and the prognostic variables.Material and methods: : Using the data from the Hospital de León Tumour Registry, weanalyzed the characteristics of all the patients diagnosed of having colo-rectal tumours between 1993and 2002. The patients were classified in two groups: one of them composed by 74 patients with MCRC,and the other formed by 1342 patients diagnosed in 1996 and 1997 of having single colo-rectal tumours.Results: The observed frequency of MCRC corresponded to 2.7 percent of the whole cases. Theage of the MCRC patients was 2 years higher than that of the patients with single neoplasms, andshowed a higher familial oncologic history, that was present in 38 percent of the cases. No differenceswere observed for location and stage of the first appeared colo-rectal neoplasm. The survival of thepatients developing metachronous MCRC was lower than for those with synchronous disease,possibly due to the higher number of the second neoplasms appearing in these patients at early stages.Prognostic values were age, sex, and metachronous or synchronous type of disease.Conclusions: MCRC is a frequent entity. The frequency of familial oncologic history is veryhigh. No significant differences were seen in relation to prognosis between single and multiple colorectalcancer
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Male , Female , Humans , Colorectal Neoplasms/epidemiology , Neoplasms, Multiple Primary/epidemiology , Survival Rate , PrognosisABSTRACT
No disponible
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Female , Aged , Aged, 80 and over , Humans , Spherocytosis, Hereditary/diagnosisABSTRACT
No disponible
Subject(s)
Female , Aged , Humans , Citalopram/adverse effects , Inappropriate ADH Syndrome/chemically induced , Selective Serotonin Reuptake Inhibitors/adverse effectsSubject(s)
Empyema, Pleural/microbiology , Pseudomonas Infections/diagnosis , Pseudomonas aeruginosa/isolation & purification , Aged , Anti-Bacterial Agents/therapeutic use , Chronic Disease , Drainage/methods , Empyema, Pleural/surgery , Fatal Outcome , Humans , Male , Pseudomonas Infections/drug therapy , Pseudomonas Infections/microbiologyABSTRACT
No disponible
Subject(s)
Male , Aged , Humans , Empyema, Pleural , Pseudomonas aeruginosa , Pseudomonas Infections , Fatal Outcome , Drainage , Chronic Disease , Anti-Bacterial AgentsSubject(s)
Adenocarcinoma/pathology , Colonic Neoplasms/pathology , Hernia, Inguinal/pathology , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/therapy , Aged , Barium Sulfate , Colonic Neoplasms/diagnostic imaging , Colonic Neoplasms/therapy , Colonoscopy , Enema/methods , Hernia, Inguinal/diagnostic imaging , Hernia, Inguinal/therapy , Humans , Male , Radiography , Treatment OutcomeABSTRACT
No disponible
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Male , Humans , Aged , Adenocarcinoma , Treatment Outcome , Hernia, Inguinal , Colonoscopy , Barium Sulfate , Enema , Colonic NeoplasmsABSTRACT
No disponible
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Female , Humans , Aged, 80 and over , Aged , Male , Urinary Tract Infections , Corynebacterium Infections , Retrospective StudiesSubject(s)
Abdomen, Acute/etiology , Anticoagulants/adverse effects , Gastrointestinal Hemorrhage/chemically induced , Gastrointestinal Hemorrhage/diagnosis , Aged , Duodenal Diseases/chemically induced , Duodenal Diseases/diagnosis , Female , Hematoma/chemically induced , Hematoma/diagnosis , HumansABSTRACT
No disponible
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Aged , Female , Humans , Anticoagulants , Duodenal Diseases , Abdomen, Acute , Gastrointestinal Hemorrhage , HematomaABSTRACT
No disponible
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Humans , Community-Acquired Infections/drug therapy , Pneumonia/drug therapy , Ofloxacin/therapeutic use , Pneumonia/microbiology , Anti-Bacterial Agents/therapeutic useABSTRACT
We report a case of bowel infection by Pneumocystis carinii (PC) that presented as an acute obstruction accompanied by intestinal hemorrhage (melena) in a HIV seropositive hemophilic patient. Laparotomy followed by resection of two plaque-like jejunal tumors was performed, and intravenous therapy with pentamidine was initiated. No other organ was found to be affected by PC (not even the lung), with the exception of the thyroid gland. To our knowledge, this is the first reported case in which acute intestinal obstruction was the presenting symptom of extrapulmonary pneumocystosis.
Subject(s)
AIDS-Related Opportunistic Infections , HIV Seropositivity/complications , Hemophilia A/complications , Intestinal Obstruction/etiology , Jejunal Diseases/etiology , Pneumocystis Infections , Thyroiditis/etiology , AIDS-Related Opportunistic Infections/diagnosis , Acute Disease , Adult , Humans , Intestinal Obstruction/surgery , Jejunal Diseases/surgery , Male , Melena/etiology , Pneumocystis Infections/diagnosisABSTRACT
We report a case of neurosarcoidosis, which simulated a cerebral tumor located at the floor of the III ventricle, associated to an aseptic meningitis and diabetes insipidus. It was the first and only manifestation of the illness. The response to steroid therapy was very favourable, with complete clinical recuperation and radiological resolution.
Subject(s)
Brain Diseases/diagnosis , Brain Neoplasms/diagnosis , Sarcoidosis/diagnosis , Aged , Diagnosis, Differential , Humans , MaleABSTRACT
Acute pancreatitis is a rare, albeit severe, secondary effect of valproic acid which is probably due to an idiosyncratic reaction. Diagnosis is based on high clinical suspicion. A new case of pancreatitis by valproic acid an a review of the literature are presented. The authors suggest that strict clinical control of the patient be carried out and pancreatic enzymes be monitored on appearance of symptoms suggestive of this complication.
