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1.
Rofo ; 181(6): 556-63, 2009 Jun.
Article in German | MEDLINE | ID: mdl-19452398

ABSTRACT

PURPOSE: To determine whether lesion scoring allows valid BI-RADS ((R)) classification and prediction of malignancy of breast lesions detectable solely with MRI. MATERIALS AND METHODS: Retrospective analysis of 86 patients who underwent MRI-guided localization and excisional biopsy of 100 breast lesions detectable only with MRI. Breast MRI was performed at 1.5 Tesla by means of a T 1w dynamic GE sequence. The positive predictive value (PPV) for malignancy was calculated for each score criterion separately, for the total score, and for corresponding BI-RADS classes. The PPV was correlated with histology. RESULTS: 31% (31/100) of breast lesions detectable only with MRI were malignant. Of the single score criteria only the lesion morphology criterion was significantly correlated with malignancy. The malignancy rate according to the breast MRI score was 0% for score 3, 18.2% for score 4, 32.1% for score 5 and each 50% for lesions of score 6 and 7. After translation into BI-RADS the malignancy rates were 0% for BI-RADS 3, 24.6% for BI-RADS 4 and 48.5% for BI-RADS 5 lesions. The thus defined BI-RADS classes were significantly correlated with malignancy. CONCLUSION: The combination of different lesion criteria to form a total breast MRI score and its translation into BI-RADS is useful in case of lesions detectable only with MRI. It enables standardized BI-RADS classification with satisfying PPV of malignancy for each BI-RADS class. Because of their low malignancy rate (18.2%), we suggest classifying lesions with a breast MRI score of 4 points as BI-RADS 4a.


Subject(s)
Algorithms , Breast Neoplasms/diagnosis , Image Interpretation, Computer-Assisted/methods , Magnetic Resonance Imaging/methods , Adult , Aged , Aged, 80 and over , Female , Humans , Image Enhancement/methods , Middle Aged , Reproducibility of Results , Sensitivity and Specificity
2.
MediCiego ; 9(supl.2): 80-83, jul. 2003. ilus
Article in Spanish | CUMED | ID: cum-22477

ABSTRACT

El síndrome de Marfan es un proceso autosómico dominante con penetrancia completa, pero de expresividad variable. Se diagnostica basándose en los datos clínicos, algunos de los cuales depende del crecimiento. En este trabajo se presenta un caso de un niño de 8 años de edad, que se ingresó en el Hospital General Docente de Morón con la variedad clínica clásica del síndrome, que mostraba afectación esquelética, ocular y cardiovascular. Se describen las características clínicas del paciente y se compara con la literatura médica revisada. Se destaca la importancia del consejo genético. (AU)


Subject(s)
INFORME DE CASO , Child , Marfan Syndrome/diagnosis , Marfan Syndrome/genetics
3.
Radiologe ; 40(6): 557-60, 2000 Jun.
Article in German | MEDLINE | ID: mdl-10929392

ABSTRACT

The authors report the case of a young patient suffering from plasmacellular osteomyelitis of the thoracic spine, a unusual localisation of this type of chronic osteomyelitis. They discuss the role of imaging diagnostic modalities in this disease, focussing on MRI.


Subject(s)
Osteomyelitis/diagnosis , Plasma Cells/pathology , Thoracic Vertebrae , Adult , Chronic Disease , Female , Fractures, Spontaneous/diagnosis , Fractures, Spontaneous/etiology , Humans , Magnetic Resonance Imaging , Osteomyelitis/complications , Spinal Fractures/diagnosis , Spinal Fractures/etiology , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/injuries , Thoracic Vertebrae/pathology , Tomography, X-Ray Computed
4.
G E N ; 46(2): 162-5, 1992.
Article in Spanish | MEDLINE | ID: mdl-1340817

ABSTRACT

Jejunal leiomyosarcoma, is an uncommon neoplasm. Diagnosis can be difficult because symptoms may be vague and nonspecific. We report the case of a 33-years-old patient, which was diagnosed and operated of this infrequent pathology.


Subject(s)
Jejunal Neoplasms/pathology , Leiomyosarcoma/pathology , Adult , Humans , Jejunal Neoplasms/surgery , Jejunum/pathology , Jejunum/surgery , Leiomyosarcoma/surgery , Male
5.
Rev. argent. cancerol ; 20(4): 162-4, 1992.
Article in Spanish | BINACIS | ID: bin-22233

ABSTRACT

El cáncer de ovario es una de las causas de muerte más común dentro de las neoplasias ginecológicas, por lo que los tratamientos de rescate son de considerable interés; así, se desarrollaron tratamientos con esquemas que contienen platino, de elección en estadios avanzados. En nuestra presente experiencia encontramos que la combinación carboplatino-ifosfamida, mesna, 4 epirrubicina y el interferón ß es una alternativa efectiva y tolerable, pues 4 de las pacientes obtuvieron respuesta completa luego de la cirugía de rescate. Para obtener conclusiones definitivas, es necesario un mayor número de pacientes y tiempo de observación. (AU)


Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Interferon-beta/therapeutic use , Carboplatin/therapeutic use , Ovarian Neoplasms/drug therapy , Ovarian Neoplasms/mortality , Neoplasm Metastasis , Cisplatin/therapeutic use
6.
Rev. argent. cancerol ; 20(4): 162-4, 1992.
Article in Spanish | LILACS | ID: lil-172439

ABSTRACT

El cáncer de ovario es una de las causas de muerte más común dentro de las neoplasias ginecológicas, por lo que los tratamientos de rescate son de considerable interés; así, se desarrollaron tratamientos con esquemas que contienen platino, de elección en estadios avanzados. En nuestra presente experiencia encontramos que la combinación carboplatino-ifosfamida, mesna, 4 epirrubicina y el interferón ß es una alternativa efectiva y tolerable, pues 4 de las pacientes obtuvieron respuesta completa luego de la cirugía de rescate. Para obtener conclusiones definitivas, es necesario un mayor número de pacientes y tiempo de observación.


Subject(s)
Humans , Female , Adult , Middle Aged , Carboplatin/therapeutic use , Interferon-beta/therapeutic use , Ovarian Neoplasms/drug therapy , Ovarian Neoplasms/mortality , Cisplatin/therapeutic use , Neoplasm Metastasis
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