Laparoscopy versus laparotomy for FIGO stage I ovarian cancer.

BACKGROUND: This is an updated version of the original review that was first published in the Cochrane Database of Systematic Reviews 2008, Issue 4. Laparoscopy has become an increasingly common approach to surgical staging of apparent early-stage ovarian tumours. This review was undertaken to assess the available evidence on the benefits and risks of laparoscopy compared with laparotomy for the management of International Federation of Gynaecology and Obstetrics (FIGO) stage I ovarian cancer. OBJECTIVES: To evaluate the benefits and harms of laparoscopy in the surgical treatment of FIGO stage I ovarian cancer (stages Ia, Ib and Ic) when compared with laparotomy. SEARCH METHODS: For the original review, we searched the Cochrane Gynaecological Cancer Group Trials (CGCRG) Register, Cochrane Central Register of Controlled Trials (CENTRAL 2007, Issue 2), MEDLINE, Embase, LILACS, Biological Abstracts and CancerLit from 1 January 1990 to 30 November 2007. We also handsearched relevant journals, reference lists of identified studies and conference abstracts. For the first updated review, the search was extended to the CGCRG Specialised Register, CENTRAL, MEDLINE, Embase and LILACS to 6 December 2011. For this update we searched CENTRAL, MEDLINE, and Embase from November 2011 to September 2016. SELECTION CRITERIA: Randomised controlled trials (RCTs), quasi-RCTs and prospective cohort studies comparing laparoscopic staging with open surgery (laparotomy) in women with stage I ovarian cancer according to FIGO. DATA COLLECTION AND ANALYSIS: There were no studies to include, therefore we tabulated data from non-randomised studies (NRS) for discussion as well as important data from other meta-analyses. MAIN RESULTS: We performed no meta-analyses. AUTHORS' CONCLUSIONS: This review has found no good-quality evidence to help quantify the risks and benefits of laparoscopy for the management of early-stage ovarian cancer as routine clinical practice.

A relação entre o aleitamento, transição alimentar e os indicadores de risco para o desenvolvimento infantil / The relation between breast-feeding, transition and child development risk

O presente estudo busca investigar a associação entre a transição alimentar e o aleitamento com a presença de risco ao desenvolvimento infantil. A amostra foi constituída de 62 díades mãe-bebê. A coleta de dados ocorreu por meio da análise da interação mãe-bebê feita com base no Protocolo de Indicadores de Risco ao Desenvolvimento Infantil (IRDIs) e de uma entrevista que investigou aspectos relativos ao aleitamento e à transição alimentar. Os dados foram organizados em categorias em relação à transição alimentar e ao aleitamento, presença ou ausência de risco ao desenvolvimento infantil, além de variáveis temporais, e analisadas estatisticamente no software STATISTICA 9.0. Os resultados apontaram que a dificuldade de transição alimentar e dificuldade de aleitamento correlacionam-se de modo significativo à presença de risco ao desenvolvimento infantil na fase de coleta dos IRDIs de 12 a 18 meses. Também está associada às variáveis idade da transição alimentar, idade da inserção de alimentação sólida, tempo de aleitamento materno e tempo de aleitamento artificial. Deste modo, a pesquisa demonstra que a dificuldade no aleitamento e na transição alimentar se associam a alterações nas interações iniciais detectáveis pelo protocolo de Índices de Risco ao Desenvolvimento Infantil, principalmente ao eixo teórico que se refere à função paterna.(AU)

The objective is to investigate the association between feeding transition, breast-feeding and child development risk. The sample consisted of 62 mother-baby dyads. Data collection occurred through the analysis of mother-baby interaction based on Child Development Risk Inventory (CDRI) and on an interview which investigated aspects related to breast-feeding and feeding transition. The data were organized in categories of feeding transition and breast-feeding, presence or absence of child development risk, and were statistically analyzed by the software STATISTICA 9.0. The results showed that the difficulty for feeding transition, mainly in relation to the introduction of solids, and for exclusive breast feeding until 6 months were signifi cantly correlated with the presence of child development risk. The research demonstrated that breast-feeding and feeding transition difficulties are associated with alterations in initial interactions, especially with the theoretical axis related to the father function.(AU)

El presente estudio investiga la asociación entre la transición nutricional y la lactancia en la presencia de riesgo para el desarrollo infantil. La muestra se consistió de 62 díadas madre-bebe. La recolección de datos ocurrió a través del análisis de la interacción madre-hijo hecha con base en el Protocolo de Indicadores de Riesgo al Desarrollo Infantil (IRDIs) y de una entrevista que investigó aspectos de la lactancia y de la trasición nutricional. Los datos fueron organizados en categorías, en relación con la transición nutricional y la lactancia; presencia o ausencia de riesgo al desarrollo infantil, además de variables temporales, y fueron analizados estadísticamente con el software STATISTICA 9.0. Los resultados mostraron que la difi cultad de la transición nutricional y la difi cultad para la lactancia se correlacioan de forma signifi cativa con la presencia de riesgo para el desarrollo del infantil en la base de recolección de los IRDIs de 12 a 18 meses. También se asocia con las variables edad de la transición nutricional; edad de incorporación de alimentos sólidos; duración de la lactancia materna y el tiempo de lactancia artificial. El estudio muestra que la dificultad con la lactancia materna y con la transición nutricional se asocian a cambios en las interaciones iniciales detectables por el Protocolo de Indicadores de Riesgo para el Desarrollo Infantil, sobre todo con el eje teórico que trata de la función paterna.(AU)

Analysis of independent risk factors for death among pediatric patients with candidemia and a central venous catheter in place.

OBJECTIVE: To use multivariate analysis to determine risk factors for death among pediatric patients with candidemia and a central venous catheter in place. DESIGN: Retrospective cohort study conducted at Santa Casa Complexo Hospitalar, a 1,200-bed teaching hospital in southern Brazil. METHODS: All cases of candidemia in pediatric patients (age,