ABSTRACT
Três grupos de voluntários, após assinatura de um termo de consentimento de participaçäo em experimento, foram submetidos a minucioso exame clínico e complementar de laboratório, bem como a uma entrevista, para se determinar qualquer alteraçäo física ou psíquica que fosse impeditiva de participaçäo no experimento. Receberam, respectivamente, por via oral, placebo, diazepam (5mg) ou Valmane (50mg), em intervalos de 8 horas aproxidamente, iniciando-se o tratamento no dia anterior ao teste, sendo a última dose administrada duas horas antes do procedimento de eliciaçäo de ansiedade, o Stroop-Color Word Test filmado (VRSCWT). A resposta de ansiedade eliciada pela situaçäo foi avaliada pelo Inventário de Ansiedade Traço-Estado de Spielberger. Os valores de ansiedade durante e após a situaçäo de teste, no grupo tratado com Valmane, näo diferiram dos valores-controle ou dos do grupo tratado com diazepam. Os resultados sugerem que o Valmane, na dose utilizada, apresenta, na situaçäo do teste de eliciaçäo de ansiedade, tendência a uma açäo semelhante ao do diazepam, apesar de menos potente. Os resultados mostraram ainda que o diazepam foi eficaz em impedir o aumento de ansiedade eliciado pela situaçäo de teste
Subject(s)
Humans , Male , Female , Adult , Anxiety/chemically induced , Valerian , Clinical Trials as Topic , Plant Extracts/therapeutic use , Stress, Psychological , Test Anxiety ScaleABSTRACT
The length of the human fetal foot was studied in 106 feet from 53 unfixed staged human fetuses (35 males and 18 females) by means of the allometric formula log Y = log b+k log X. The gestational age ranged from 13 to 26 weeks postconception. The measurement taken from the heel to the tip of the longest toe was regarded here as the maximum length of the foot. Growth in length of the foot was analysed in relation to crown-rump length. Our results show that foot length growth is correlated to crown-rump growth and is allometrically positive. No statistically significant difference was found between right and left feet or between male and female fetuses.
Subject(s)
Embryonic and Fetal Development , Foot/anatomy & histology , Foot/embryology , Abortion, Spontaneous , Female , Gestational Age , Humans , Male , PregnancyABSTRACT
We studied metatarsal growth in 600 metatarsal bones (60 pairs of feet) taken from 60 human fetuses (35 males and 25 females) ranging in age from 13 to 24 weeks postconception. The data obtained for the total length (TL) and for the ossified metatarsal length (OML) were correlated to fetal crown-rump length (C-R). The ossified metatarsal length presented a growth rate greater than the total length growth rate. There was no statistical difference between either the right and left metatarsals or males and females in total length and ossified metatarsal length growth during the period studied. We believe that metatarsal growth curves could be used to monitor fetal foot growth.
