ABSTRACT
The seroprevalence study for leptospirosis in bovines and humans was realized in family holder farms along the Transamazon Highway. The prevalence of bovine leptospirosis was 97% [90.9 - 99.5%] of farms with at least one positive animal according to microscopic agglutination test for the leptospirosis diagnostic. In 61.2% of the tested herds, the serovar hardjo was the most common, followed by the serovar bratislava (9%) and the serovar shermani (4.5%). The serologic prevalence of leptospirosis in humans was 32.8% [23.4 - 43.5%] in family groups with at least one positive individual according to microscopic agglutination test for the leptospirosis diagnostic. In 9% of family groups, the serovar bratislava was the most common, while serovar hardjo and grippotyphosa accounted for 6% and 4.5%, respectively. The impact of these results is discussed in relation to animal production and public health. Suggestions have been proposed in order to improve the situation in the region.
Subject(s)
Cattle Diseases/epidemiology , Leptospirosis/epidemiology , Leptospirosis/veterinary , Animals , Brazil/epidemiology , Cattle , Cattle Diseases/diagnosis , Humans , Leptospirosis/diagnosis , Prevalence , Rural Population , Seroepidemiologic StudiesABSTRACT
The seroprevalence study for leptospirosis in bovines and humans was realized in family holder farms along the Transamazon Highway. The prevalence of bovine leptospirosis was 97% [90.9 - 99.5%] of farms with at least one positive animal according to microscopic agglutination test for the leptospirosis diagnostic. In 61.2% of the tested herds, the serovar hardjo was the most common, followed by the serovar bratislava (9%) and the serovar shermani (4.5%). The serologic prevalence of leptospirosis in humans was 32.8% [23.4 - 43.5%] in family groups with at least one positive individual according to microscopic agglutination test for the leptospirosis diagnostic. In 9% of family groups, the serovar bratislava was the most common, while serovar hardjo and grippotyphosa accounted for 6% and 4.5%, respectively. The impact of these results is discussed in relation to animal production and public health. Suggestions have been proposed in order to improve the situation in the region..
Realizou-se o estudo da soroprevalência da leptospirose em bovinos e humanos especificamente em propriedades familiares na região de fronteira agrícola da rodovia Transamazônica, na Amazônia Oriental. A prevalência da leptospirose bovina foi 97% [90,9 99,5%] de propriedades com pelo menos um animal positivo na soroaglutinação microscópica para o diagnóstico da leptospirose. Em 61,2% dos rebanhos o sorotipo hardjo foi apontado como o mais provável, em 9% deles o sorotipo bratislava e em 4,5% o shermani. A prevalência sorológica da leptospirose humana foi 32,8% [23,4 43,5%] de núcleos familiares com pelo menos um indivíduo positivo na soroaglutinação microscópica para o diagnóstico da leptospirose. Em 9% dos núcleos familiares o sorotipo bratislava foi apontado como o mais provável, em 6% deles o sorotipo hardjo e em 4,5% o grippotyphosa. Foi discutido o impacto desses achados sobre a produção animal e saúde pública na região e feitas sugestões para minorar o problema.
Subject(s)
Animals , Cattle , Humans , Cattle Diseases/epidemiology , Leptospirosis/epidemiology , Leptospirosis/veterinary , Brazil/epidemiology , Cattle Diseases/diagnosis , Leptospirosis/diagnosis , Prevalence , Rural Population , Seroepidemiologic StudiesABSTRACT
Leptospira is a highly diverse genus comprising many species and serogroups in Brazil as well as all over the world. However, a study by arbitrarily primed PCR of 44 leptospiral strains isolated from humans during three different outbreaks in Brazilian urban centers reveals that 43 of 44 isolates exhibit very similar fingerprints. Analysis of these isolates indicates that they belong to a clonal subpopulation of Leptospira interrogans sensu stricto.
Subject(s)
Disease Outbreaks , Leptospira interrogans/classification , Leptospirosis/epidemiology , Leptospirosis/parasitology , Brazil/epidemiology , Clone Cells , DNA Fingerprinting , Humans , Molecular Epidemiology , Polymerase Chain Reaction/methods , Urban PopulationABSTRACT
A evoluçäo da doença causada pela inoculaçäo intraperitoneal de Mycobacterium bovis (cepa AN5) foi avaliada em hamsters (Mesocricetus auratus) tratados de segundas a sextas-feiras, com doses subcutâneas de 30 mg/kg de Triclorfon, por um período de 8 semanas consecutivas. Os critérios adotados para essa avaliaçäo foram o tempo de sobrevivência após a inoculaçäo e a quantificaçäo do agente no baço, fígado, rim e pulmäo colhidos aos 1, 15, 29 e 45 dias após a inoculaçäo. Nessas oportunidades também foram realizados exames histopatológicos. Os animais do grupo tratado com Triclorfon e do grupo controle desenvolveram tuberculose progressiva. Os resultados da quantificaçäo do agente nos órgäos examinados, e do tempo de sobrevivência após a inoculaçäo, näo mostraram qualquer influência da administraçäo do Triclorfon
